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Visual function in young adults following intrauterine growth retardation

Background: Intrauterine growth retardation (IUGR) resulting in infants born small for gestational age is a known risk factor for neurologic deficits and may predispose to poor cognitive development later in life. We recently found an association between IUGR and a reduced neuroretinal rim area at 18 years of age. We evaluated the possible association between IUGR and visual function. Subjects and

Social capital, the miniaturisation of community and self-reported global and psychological health.

Social capital is often operationalised as social participation in the activities of the formal and informal networks of civil society and/or as generalised trust. Social participation and trust are two aspects of social capital that mutually affect each other, according to the literature. In recent years there has been an increased attention to the fact that generalised trust decreases for every

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I Norge liksom i Sverige har det visat sig att det finns ett stort behov av en lärobok på universitetens grundutbildning i dramatikanalys. I Norge är det mer än 25 år sedan som en sådan bok kom ut. För fem år sedan var situationen densamma i Sverige. Frode Hellands och Lisbeth Pettersen Wærps bok Å lese drama. Innføring i teori og analyse är därför välkommen – inte minst därför att den som titeln

Picosecond X-ray diffraction studies of laser-excited acoustic phonons in InSb

We have employed time-resolved X-ray diffraction with picosecond temporal resolution to measure the time-dependent rocking curves of laser-irradiated asymmetrically cut single InSb crystals. Coherent acoustic phonons were excited in the crystals by irradiation with 800-nm, 100-fs laser pulses at irradiances between 0.25 and 12 mJ/cm(2). The induced time-dependent strain profiles (corresponding to

Type 1 diabetes risk analysis on dried blood spot samples from population-based newborns: design and feasibility of an unselected case-control study

Development of type 1 diabetes mellitus (T1D) may be triggered pre- or perinatally by multiple factors. Identifying new predisposing T1D markers or combinations of markers in a large, well-characterised case-control collection may be important for future T1D prevention. The present work describes the design and feasibility of a large and unselected case-control study, which will define and evaluat

Enhanced concentration of COMP (cartilage oligomeric matrix protein) in osteochondral fractures from racing Thoroughbreds

The aim of the present study was to correlate the levels of COMP and aggrecan as indicators of tissue damage, in synovial fluid (sf) from carpal joints of acutely lame racehorses, with macroscopical lesions of articular cartilage (OA). osteochondral fractures and ligament tears found at arthroscopy. Sixty-three lame horses [49 Standardbred trotters (STB) and 14 Thoroughbreds (TB)] in conventional

Inhibition of cerebrospinal fluid formation by omeprazole

Omeprazole, a specific inhibitor of H(+)-K(+)-activated ATPase, gave a dose-dependent inhibition of CSF production as determined by cerebroventriculocisternal perfusions in the rabbit. The reduction was 35% when the perfusate concentration of omeprazole was 10(-6) M and 25% after an intravenous dose of 0.2 mg/kg of omeprazole, respectively. A similarly substituted benzimidazol (H178/42) without H(

A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans

Systemic lupus erythematosus (SLE, OMIM 152700) is a complex autoimmune disease that affects 0.05% of the Western population, predominantly women(1-4). A number of susceptibility loci for SLE have been suggested in different populations, but the nature of the susceptibility genes and mutations is yet to be identified(5-9). We previously reported a susceptibility locus (SLEB2) for Nordic multi-case

Atmospheric transport of polybrominated diphenyl ethers and polychlorinated biphenyls to the Baltic sea

The atmospheric transport of polybrominated diphenyl ethers (PBDEs) and polychlorinated biphenyls (PCBs) was compared by measuring concentrations in air and deposition on an island located in the central basin of the Baltic Sea. Median SigmaPBDE and SigmaPCB concentrations (gaseous + particle) were 8.6 and 7.4 pg m(-3), respectively. Airborne PCBs were mainly found in the gaseous phase, while most

Calcium-(organo)aluminum-proton competition for adsorption to tomato root cell walls: Experimental data and exchange model calculations

Aluminum interacts with negatively charged surfaces in plant roots, causing inhibition of growth and nutrient uptake in plants growing on acid soils. Pectins in the root cell wall form the major cation adsorption surface, with Ca2+ as the main adsorbing cation. Adsorption of Al3+ and Ca2+ to isolated cell wall material of tomato (Lycopersicon esculentum L.) roots was examined at pH 3.00-4.25 and i

A predatory democracy? An essay on taxation in classical Athens

Predatory rule is defined here as a tendency to maximize state revenue, subject to the rulers′ relative bargaining power and transaction costs (Levi, M., 1988, Of Rule and Revenue. Berkeley: Univ. California Press; North, D. C., 1981, Structure and Change in Economic History. New York: Norton). I suggest that the implicit bargaining between Athenian "politicians" and the poor majority generated pr

Magnetotransport properties of short period GaMnAs/InGaAs superlattices

Magnetotransport properties of GaMnAs/InGaAs superlattice structure and GaMnAs/GaAs single layers have been investigated from 4 to 300 K and magnetic fields up to 22.5 T. All these magnetic semiconductors show the so-called "paramagnetic-to-ferromagnetic phase transition''. However, in GaMnAs/InGaAs superlattice beside the Curie Wiess temperature (T-c similar to 40 K), a new phase transition is ob

Pharmacokinetics of Na2B12H11SH (BSH) in patients with malignant brain tumours as prerequisite for a phase I clinical trial of boron neutron capture

The disposition of Na2B12H11SH (BSH) in patients with malignant glioma has been investigated, in preparation for a Phase I clinical trial of boron neutron capture therapy. BSH was found to possess a linear disposition over the dosage interval investigated (up to 75 mg/kg). A bi-phasic blood pharmacokinetics was observed. Tumour-to-blood ratios showed variations between patients between 0.08 and 5.

Tunable surface plasma resonance frequency in Ag core/Au shell nanoparticles system prepared by laser ablation

A method for preparation of Ag core/Au shell nanoparticles with tunable surface plasma resonance (SPR) band was presented and studied. It was found that the tunable SPR band could be significantly conducted and achieved by laser ablation to Au plate in Ag colloidal solution, leading to the formation of Ag core/Au shell structure by the deposition of Au atoms on the surface of Ag nanoparticles. Dep

Neurobiology in primary headaches.

Primary headaches such as migraine and cluster headache are neurovascular disorders. Migraine is a painful, incapacitating disease that affects a large portion of the adult population with a substantial economic burden on society. The disorder is characterised by recurrent unilateral headaches, usually accompanied by nausea, vomiting, photophobia, and/or phonophobia. A number of hypothesis have em

Utilizing identity-by-descent probabilities for genetic fine-mapping in population based samples, via spatial smoothing of haplotype effects

Genetic fine mapping can be performed by exploiting the notion that haplotypes that are structurally similar in the neighbourhood of a disease predisposing locus are more likely to harbour the same susceptibility allele. Within the framework of Generalized Linear Mixed Models this can be formalized using spatial smoothing models, i.e. inducing a covariance structure for the haplotype risk paramete

Cationic agents for DNA compaction

Fluorescence microscopy was used to investigate the conformational changes of individual T4 DNA molecules induced by different compacting agents, namely the cationic surfactants, cetyltrimethylammonium bromide (CTAB) and chloride (CTAC), iron(III), lysozyme, and protamine sulfate. A protocol for establishing size estimates is suggested to obtain reproducible results. Observations show that in the

Enigmatic Late Cretaceous high palaeo-latitude lonestones in Chukotka, northeasternmost Asia

Well-rounded cobbles were encountered within a low-energy restricted marine organic-rich deposit of latest Cretaceous age in Chukotka, NE Asia. The clasts are hydrodynamically incompatible with the inferred quiet depositional environment of the host sediment. Driftwood capable of tree-rafting, glacial striations, gastrolith clast clustering, and disrupting clast impact impressions typical of volca