BACKGROUND: Oestrogen receptor alpha (ER) is involved in cell growth and proliferation and functions as a transcription factor, a transcriptional coregulator, and in cytoplasmic signalling. It affects, for example, bone, endometrium, ovaries and mammary epithelium. It is a key biomarker in clinical management of breast cancer, where it is used as a prognostic and treatment-predictive factor, and a

α-Synuclein (α-Syn), is an intrinsically disordered protein present in the substantia nigra part of the brain. α-Syn is commonly known to associate with lipid membranes containing anionic lipids. Hence, the protein is hypothesized to be involved in the vesicle trafficking at the synapses, but there are yet many unanswered questions regarding the full physiological role of the protein. During the d

During the past decade, many parliamentary democracies have experienced bargaining delays when forming governments. The previous literature has attributed protracted government formation processes to a high degree of preference uncertainty among the political parties and a high level of bargaining complexity. The article draws on such theories, but also adds a third theoretical mechanism, commitme

[The project Millora 2.0: Results 2018–2022] Based on repeated yearly surveys of the vascular plant flora in 120 hectar plots in the province of Scania, southernmost Sweden, analysed in combination with speciesspecific traits and ecological indicator values (EIVs), changes in the flora and vegetation over the last four years are reported. Many of the changes observed, such as significant increasesBased on repeated yearly surveys of the vascular plant flora in 120 hectar plots in the province of Scania, southernmost Sweden, analysed in combination with speciesspecific traits and ecological indicator values (EIVs), changes in the flora and vegetation over the last four years are reported. Many of the changes observed, such as significant increases in lightdemanding, shortlived, pollinatorind

Why do some individuals feel hostility and express bias against supporters of other political parties? Drawing on intergroup threat theory, we examine the role of emotions as a mechanism by which perceived threats against the ingroup are a source of increased affective polarization. In two survey experiments performed in the multiparty contexts of Sweden (N = 505) and Germany (N = 776), we manipul

Introduction: How does threat motivate political choices? An extensive literature has noted the importance of threat in influencing political behavior. A growing literature in political psychology has used the concept of “mortality salience” to examine the role of existential threat in political decisions. Scholars have argued that inducing mortality salience by asking individuals to think about t

Why do political parties negotiate coalition agreements? Many coalition cabinets negotiate lengthy coalition contracts outlining the agenda for the time in office. Negotiating such an agreement not only takes time and resources, but compromises have to be made which may result in cabinet conflicts and electoral costs. We argue that coalition agreements are important control devices that allow coal

Diagnosis and treatment of patients with suspected chronic coronary syndrome (CCS) currently relies on the degree of coronary artery stenosis and its significance for myocardial perfusion. However, myocardial perfusion can be affected by factors other than coronary stenosis. The aim of this study was to investigate to what extent sex, age, diabetes, hypertension and smoking affect quantitative myo

Recent research has used the work of Douglas North as the foundation on which the case of institutions as ultimate driver of development could be built.North describes institutions as 'the humanly devised constraints that shape human interaction'. These arepowerful metaphors for us who are accustomed to think in terms of'constrained maximization' as the rule guiding personal actions. This book exp

This paper draws on the codes of ethics of a wide range of countries to propose an ideal one for a newly constituted press regulatory body in the United Kingdom. It also suggests the adoption of a codes of ethics and including a conscience clause in press journalists’ contract which would protect them from being coerced into doing clearly unethical work.

This interview is part of a major research project that is based on interviews and discussions with influential decision-makers, facilitators, mediators and negotiators who were involved in Arab-Israeli peace negotiations over the past three decades, as well as on archival research in Oslo, London, Washington and Jerusalem. Semi-structured in-depth interviews were conducted with more than 80 Israe

BackgroundMost jurisdictions that allow euthanasia and assisted suicide (AS) regulate it through the medical profession. However, the extent and nature of how medicine should be involved are debated. Swiss AS practice is unusual in that it is managed by lay AS organizations that rely on a law that permits AS when done for nonselfish reasons. Physicians are not mentioned in the law but are usually

Accurate statistical characterization of electromagnetic propagation is necessary for the design and deployment of radio systems. State-of-the-art channel models such as the Enhanced COST 2100 Channel Model utilize the concept of clusters of multipath components, and characterize channels by their inter- and intra-cluster statistics. Automatic clustering algorithms have been proposed in literature

Stored energies of radiating systems have generated research interest for several decades due to their relationship with Q-factor and fractional bandwidth. In this paper material derivatives are used to provide a new interpretation of widely used stored energy expressions. This provides a fundamental relationship between stored energies of radiating systems and their electromagnetic material prope

De senaste åren har Havs- och vattenmyndigheten minskat den mängd siklöja som får fångas i Bottenviken. Minskningen beror på att beståndet av siklöja har minskat. Siklöjan fiskas framförallt för att framställa löjrom. Det innebär att fiskarnas intäkter är starkt beroende av priset på löjrom. Mindre fångster innebär lägre intäkter för fiskarna om inte priset på löjrom samtidigt stiger kraftigt.I de

The dramatic increase of asylum seekers entering the EU in 2015 profoundly changed migration politics in many EU countries. Not least in Sweden which accepted more migrants per capita than any other EU country but then swung abruptly to become among the strictest recipient countries. We use Sweden as a critical and extreme case to argue that the rapid shift in asylum politics and public opinion to

I november 2016 öppnade Stockholms fiskauktion. En tanke var att kortare avstånd mellan fiskare och konsumenter i Stockholmsregionen skulle gynna lokala fiskare, konsumenter och miljö. Om lokalt fångad fisk värderas på marknaden kan priserna påverkas. Vi undersöker om lokalt fångad gös fick en prispremie på Stockholmsauktionen och om priserna på gös påverkades i andra försäljningskanaler. Vi finne

The β-coronavirus family, encompassing Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), Severe Acute Respiratory Syndrome Coronavirus (SARS), and Middle East Respiratory Syndrome Coronavirus (MERS), has triggered pandemics within the last two decades. With the possibility of future pandemics, studying the coronavirus family members is necessary to improve knowledge and treatment. Thes

Den mängd havskräfta som säljs på den svenska marknaden är idag långt mindre än den tillgängliga kvoten. Skulle fiskarna få möjlighet att sälja mer havskräftor ökar intäkterna, men det kan också leda till att priserna blir lägre. I den här studien analyserar vi hur priserna påverkas om mer trålfiskad havskräfta säljs på marknaden. Resultaten visar att:Om mängden trålfiskad havskräfta ökar med 5 pr