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A Population-Based Study on the Incidence, Risk Factors, and Outcome of Salmonella Bloodstream Infections in South Sweden 2012–2022

IntroductionInvasive infections caused by Salmonella are a significant global health concern. This population-based study aimed to comprehensively analyze invasive Salmonella infections in South Sweden, focusing on incidence, clinical presentation, risk factors, and outcomes.MethodsThis population-based observational cohort study, conducted from 2012 to 2022, included all patients with Salmonella

Depletion-induced crystallization of anisotropic triblock colloids

The intricate interplay between colloidal particle shape and precisely engineered interaction potentials has paved the way for the discovery of unprecedented crystal structures in both two and three dimensions. Here, we make use of anisotropic triblock colloidal particles composed of two distinct materials. The resulting surface charge heterogeneity can be exploited to generate regioselective depl

Test Equipment for the LUCAS Chest Compression System: Incorporating Biomechanical Insights for Future Design Enhancements

En inkluderande och justerbar modell av den mänskliga bröstkorgen för framtidens testning av HLR-utrustning Att testa och validera medicinsk utrustning på människor är etiskt komplicerat, praktiskt problematiskt och i vissa fall direkt farligt. Ett konkret exempel är en mekanisk hjärt- och lungräddningsmaskin, där utförandet av hjärtkompressioner utan hjärtstopp kan vara skadligt. Därför krävs teThe LUCAS Chest Compression System is a market leading mechanical cardiopulmonary resuscitation device, assisting medical professionals worldwide when treating patients with sudden cardiac arrest. The objective of this master thesis project was to develop a new, adjustable test equipment for the LUCAS device, allowing for tests on varying chest heights and stiffness levels. Product development str

Interfacial Fluid Rheology of Soft Particles

In situ interfacial rheology and numerical simulations are used to investigate microgel monolayers in a wide range of packing fractions, ζ2D. The heterogeneous particle compressibility determines two flow regimes characterized by distinct master curves. To mimic the microgel architecture and reproduce experiments, an interaction potential combining a soft shoulder with the Hertzian model is introd

Selective and Concentrative Enteropancreatic Recirculation of Antibiotics by Pigs

Antibiotics that are efficacious for infectious pancreatitis are present in pancreatic exocrine secretion (PES) after intravenous administration and above minimal inhibitory concentrations. We measured concentrations of four antibiotics by tandem liquid chromatography–mass spectroscopy in plasma and PES after enteral administration to juvenile pigs with jugular catheters and re-entrant pancreatic-

A colloidal viewpoint on the sausage catastrophe and the finite sphere packing problem

It is commonly believed that the most efficient way to pack a finite number of equal-sized spheres is by arranging them tightly in a cluster. However, mathematicians have conjectured that a linear arrangement may actually result in the densest packing. Here, our combined experimental and simulation study provides a physical realization of the finite sphere packing problem by studying arrangements

Exploring the 3D Conformation of Hard-Core Soft-Shell Particles Adsorbed at a Fluid Interface

The encapsulation of a rigid core within a soft polymeric shell allows obtaining composite colloidal particles that retain functional properties, e.g., optical or mechanical. At the same time, it favors their adsorption at fluid interfaces with a tunable interaction potential to realize tailored two-dimensional (2D) materials. Although they have already been employed for 2D assembly, the conformat

Real-Time In Situ Observation of CsPbBr3 Perovskite Nanoplatelets Transforming into Nanosheets

The manipulation of nano-objects through heating is an effective strategy for inducing structural modifications and therefore changing the optoelectronic properties of semiconducting materials. Despite its potential, the underlying mechanism of the structural transformations remains elusive, largely due to the challenges associated with their in situ observations. To address these issues, we synth

Being a non-native English speaker in science and medicine

The use of English language as the official language in science had an undoubtable role in moving science forward but posed an extra challenge for people whose first language is not English. In this Viewpoint, six non-Native English speakers share their experience as academics, clinicians, researchers and editors who carry out the core tasks of their jobs in a second language, and suggest potentia

Flexible Colloidal Molecules with Directional Bonds and Controlled Flexibility

Colloidal molecules are ideal model systems for mimicking real molecules and can serve as versatile building blocks for the bottom-up self-assembly of flexible and smart materials. While most colloidal molecules are rigid objects, the development of colloidal joints has made it possible to endow them with conformational flexibility. However, their unrestricted range of motion does not capture the

Buckling and Interfacial Deformation of Fluorescent Poly(N-isopropylacrylamide) Microgel Capsules

Hollow microgels are fascinating model systems at the crossover between polymer vesicles, emulsions, and colloids as they deform, interpenetrate, and eventually shrink at higher volume fraction or when subjected to an external stress. Here, we introduce a system consisting of microgels with a micrometer-sized cavity enabling a straightforward characterization in situ using fluorescence microscopy

Vitamin D insufficiency in infants with increased risk of developing type 1 diabetes : A secondary analysis of the POInT Study

Background Vitamin D insufficiency (VDI) may be a factor in the development of type 1 diabetes (T1D). The aim of this study is to investigate the presence and persistence of VDI in a large cohort of infants with increased risk of developing T1D, in light of the differences in local supplementation guidelines. Methods In the POInT Study, a multicentre primary prevention study between February 2018

Association between dietary pesticide exposure profiles and body weight change in French adults : Results from the NutriNet-Santé cohort

BACKGROUND: Pesticides cause a wide range of deleterious health effects, including metabolic disorders. Little is known about the effects of dietary pesticide exposure on body weight (BW) change in the general population. We aimed to investigate the role of dietary pesticide exposure in BW change among NutriNet-Santé participants, focusing on potential sexual dimorphism.METHODS: Participants compl

The association between water intake and future cardiometabolic disease outcomes in the Malmö Diet and Cancer cardiovascular cohort

The aim of this study was to explore the longitudinal association between reported baseline water intake and incidence of coronary artery disease (CAD) and type 2 diabetes in the Malmö Diet and Cancer Cohort (n = 25,369). Using cox proportional hazards models, we separately modelled the effect of plain and total (all water, including from food) water on CAD and type 2 diabetes risk, whilst adjusti

Terahertz permittivity parameters of monoclinic single crystal lutetium oxyorthosilicate

The anisotropic permittivity parameters of monoclinic single crystal lutetium oxyorthosilicate, Lu2SiO5 (LSO), have been determined in the terahertz spectral range. Using terahertz generalized spectroscopic ellipsometry (THz-GSE), we obtained the THz permittivities along the a, b, and c ⋆ crystal directions, which correspond to the ϵ a , ϵ b , and ϵ c ⋆ on-diagonal tensor elements. The associated

Diagnostic Accuracy of the Swedish Version of the Multicultural Cognitive Examination for Cognitive Assessment in Swedish Memory Clinics

Background: Cognitive assessment for foreign-born individuals is suboptimal. The Multicultural Cognitive Examination (MCE) was developed for use in culturally, linguistically and educationally diverse populations. The MCE includes the Rowland Universal Dementia Assessment Scale (RUDAS) and performs assessment of memory, verbal fluency, and visuospatial function. Objective: To compare the psychomet

Condition-transfer maternal effects modulate inter-locus sexual conflict

Strong sexual selection frequently favors males that increase their reproductive success by harming females, with potentially negative consequences for natural populations. Understanding what factors modulate conflict between the sexes is hence critical to understand both the evolution of male and female phenotypes and the viability of populations in the wild. Here, we model the evolution of male

Numerical Modeling of Chemical Kinetics, Spray Dynamics, and Turbulent Combustion towards Sustainable Aviation

With growing interest in sustainable civil supersonic and hypersonic aviation, there is a need to model the combustion of alternative, sustainable jet fuels. This work presents numerical simulations of several related phenomena, including laminar flames, ignition, and spray flames. Two conventional jet fuels, Jet A and JP-5, and two alternative jet fuels, C1 and C5, are targeted. The laminar burni

SYSTEMATIC POSITION AND CONSERVATION ASPECTS OF MELINAEA MNASIAS THERA (LEPIDOPTERA: NYMPHALIDAE: DANAINAE)

The tribe Ithomiini (Nymphalidae: Danainae) includes nearly 400 species of butterflies distributed from Mex-ico to Northern Argentina, and adults of all species are aposematic and the main models in several Neotropical mimicry rings. The subtribe Melinaeina, a small group composed of five genera of large ithomiines, is the sister group of all remaining groups in the tribe Ithomiini. With 14 recogn