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Genetic interaction analysis among oncogenesis-related genes revealed novel genes and networks in lung cancer development

The development of cancer is driven by the accumulation of many oncogenesis-related genetic alterations and tumorigenesis is triggered by complex networks of involved genes rather than independent actions. To explore the epistasis existing among oncogenesis-related genes in lung cancer development, we conducted pairwise genetic interaction analyses among 35,031 SNPs from 2027 oncogenesis-related g

The Choice of Legal Basis for Acts of the European Union : Competence Overlaps, Institutional Preferences, and Legal Basis Litigation

This book provides the first comprehensive discussion of conflicts between legal bases in EU law. It fills an important gap in the existing literature on the choice of legal basis in EU law by analysing the structure of legal bases and the resulting legal basis litigation in the European Union, thus identifying areas of conflict produced by overlapping competences, divergent inter-institutional in

Complex Scheduling with Potts Neural Networks

In a recent paper (Gislén et al. 1989) a convenient encoding and an efficient mean field algorithm for solving scheduling problems using a Potts neural network was developed and numerically explored on simplified and synthetic problems. In this work the approach is extended to realistic applications both with respect to problem complexity and size. This extension requires among other things the in

Negative Full Counting Statistics Arise from Interference Effects

The Keldysh-ordered full counting statistics is a quasiprobability distribution describing the fluctuations of a time-integrated quantum observable. While it is well known that this distribution can fail to be positive, the interpretation and origin of this negativity has been somewhat unclear. Here, we show how the full counting statistics can be tied to trajectories through Hilbert space, and ho

Quantum heat engines based on electronic Mach-Zehnder interferometers

We theoretically investigate the thermoelectric properties of heat engines based on Mach-Zehnder interferometers. The energy dependence of the transmission amplitudes in such setups arises from a difference in the interferometer arm lengths. Any thermoelectric response is thus of purely quantum-mechanical origin. In addition to an experimentally established three-terminal setup, we also consider a

Physical Implementations of Quantum Absorption Refrigerators

Absorption refrigerators are autonomous thermal machines that harness the spontaneous flow of heat from a hot bath into the environment in order to perform cooling. Here we discuss quantum realizations of absorption refrigerators in two different settings: namely, cavity and circuit quantum electrodynamics. We first provide a unified description of these machines in terms of the concept of virtual

Higgs-boson-plus-photon production at the CERN Large Hadron Collider : A clean probe of the b-quark parton densities

Higgs boson production in association with a high pT photon at the CERN Large Hadron Collider is analyzed, in the framework of the MSSM model, for the heavier neutral Higgs bosons. The request of an additional photon in the exclusive Higgs boson final state selects b-quark pairs among the possible initial partonic states, since gluon-gluon initial states are not allowed by C-parity conservation. H

Odderon-Pomeron interference

We show that the asymmetry in the fractional energy of charm versus anticharm jets produced in high energy diffractive photoproduction is sensitive to the interference of the Odderon (C=-) and Pomeron (C=+) exchange amplitudes in QCD. We predict the dynamical shape of the asymmetry in a simple model and estimate its magnitude to be of the order 15% using an Odderon coupling to the proton which sat

Where and when the earliest coccolithophores?

New calcareous nannofossil analyses from the Northern Calcareous Alps of Austria are herein used to update and improve the state of knowledge about the oldest occurrence of coccolithophores reported in the literature. Previously reported Norian occurrences of coccoliths were based on an obsolete Triassic chronostratigraphy, in which the Rhaetian stage was subsumed into the Norian ('Sevatian 2'). T