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High density supercritical carbon dioxide for the extraction of pesticide residues in onion with multivariate response surface methodology

The excessive use of pesticides is a serious health problem due to their toxicity and bioaccumulation through the food chain. Due to the complexity of foods, the analysis of pesticides is challenging often giving large matrix effects and co‐extracted compounds. To overcome this problem, a selective and “green” supercritical fluid extraction method was developed, using neat carbon dioxide as a solv

Measurement of electrons from heavy-flavour hadron decays as a function of multiplicity in p-Pb collisions at √sNN = 5.02 TeV

The multiplicity dependence of electron production from heavy-flavour hadron decays as a function of transverse momentum was measured in p-Pb collisions at sNN = 5.02 TeV using the ALICE detector at the LHC. The measurement was performed in the centre-of-mass rapidity interval −1.07 < ycms< 0.14 and transverse momentum interval 2 < pT< 16 GeV/c. The multiplicity dependence of the production of ele

A Naturalistic Perspective on Knowledge How : Grasping Truths in a Practical Way

For quite some time, cognitive science has offered philosophy an opportunity to address central problems with an arsenal of relevant theories and empirical data. However, even among those naturalistically inclined, it has been hard to find a universally accepted way to do so. In this article, we offer a case study of how cognitive-science input can elucidate an epistemological issue that has causeFor quite some time, cognitive science has offered philosophy an opportunity to address central problems with an arsenal of relevant theories and empirical data. However, even among those naturalistically inclined, it has been hard to find a universally accepted way to do so. In this article, we offer a case study of how cognitive-science input can elucidate an epistemological issue that has cause

Virtual Drive Testing Over-the-Air for Vehicular Communications

Multiple-input multiple-output (MIMO) over-the-air (OTA) testing is a standardized procedure to evaluate the performance of MIMO-capable devices such as mobile phones and laptops. With the growth of the vehicle-to-everything (V2X) service, the need for vehicular communication testing is expected to increase significantly. The so-called multi-probe anechoic chamber (MPAC) setup is standardized for

Genome-wide association study of angioedema induced by angiotensin-converting enzyme inhibitor and angiotensin receptor blocker treatment

Angioedema in the mouth or upper airways is a feared adverse reaction to angiotensin-converting enzyme inhibitor (ACEi) and angiotensin receptor blocker (ARB) treatment, which is used for hypertension, heart failure and diabetes complications. This candidate gene and genome-wide association study aimed to identify genetic variants predisposing to angioedema induced by these drugs. The discovery co

A modified caseload midwifery model for women with fear of birth, women's and midwives' experiences : A qualitative study

OBJECTIVE: Although fear of birth is common during pregnancy and childbirth, the best treatment for fear of birth in clinical care remain unclear. Strong evidence suggests that continuity models of midwifery care can benefit women and birth outcomes, though such models are rare in Sweden. Because women with fear of birth could benefit from such models, the aim of this qualitative study was to exam

You never fake alone. Creative AI in action

Creative AI (notably GANs and VAEs) can generate convincing fakes of video footage, pictures, graphics, etc. In order to conceptualize the societal role of creative AI a new conceptual toolbox is needed. The paper provides metaphors and concepts for understanding the functioning of creative AI. It shows how the role of creative AI in relation to FAT ideals can be enriched by a dynamic and construc

Numerical study of heat transfer in gravity-driven particle flow around tubes with different shapes

In the present paper, the heat transfer of gravity-driven dense particle flow around five different shapes of tubes is numerically studied using discrete element method (DEM). The velocity vector, particle contact number, particle contact time and heat transfer coefficient of particle flow at different particle zones around the tube are carefully analyzed. The results show that the effect of tube

The Surgeon's Role in the Opioid Crisis : A Narrative Review and Call to Action

Over the past two decades, there has been a sharp rise in the use of prescription opioids. In several countries, most notably the United States, opioid-related harm has been deemed a public health crisis. As surgeons are among the most prolific prescribers of opioids, growing attention is now being paid to the role that opioids play in surgical care. While opioids may sometimes be necessary to pro

X-ray absorption spectroscopy principles and practical use in materials analysis

The X-ray Absorption Fine Structure (XAFS) with its subregions X-ray Absorption Near-edge Structure (XANES) and Extended X-ray Absorption Fine Structure (EXAFS) is a powerful tool for the structural analysis of materials, which is nowadays a standard component of research strategies in many fields. This review covers a wide range of topics related to its measurement and use: the origin of the fine

Simple one pot preparation of chemical hydrogels from cellulose dissolved in cold LiOH/Urea

In this work, non-derivatized cellulose pulp was dissolved in a cold alkali solution (LiOH/urea) and chemically cross-linked with methylenebisacrylamide (MBA) to form a robust hydrogel with superior water absorption properties. Different cellulose concentrations (i.e., 2, 3 and 4 wt%) and MBA/glucose molar ratios (i.e., 0.26, 0.53 and 1.05) were tested. The cellulose hydrogel cured at 60 °C for 30

Complement inhibitor factor H expressed by breast cancer cells differentiates CD14+ human monocytes into immunosuppressive macrophages

Macrophages are a major immune cell type in the tumor microenvironment, where they display a tumor-supporting phenotype. Factor H (FH) is a complement inhibitor that also plays a role in several cellular functions. To date, the phenotype of monocytes stimulated with FH has been unexplored. We discovered that FH is a survival factor for CD14+ primary human monocytes, promoting their differentiation

Revisiting the problem of credibility in the age of post-truth

This essay raises the question whether citizens in the digital age can learn from how credibility is treated in international negotiations. Negotiators face problems both in attempting to send credible signals and in making credibility assessments of received signals. Several studies, starting with Schelling's seminal analysis of commitments, indicate that credible signals are those that are someh

Addition of biological therapies to palliative chemotherapy prolongs survival in patients with peritoneal carcinomatosis of colorectal origin

OBJECTIVES: Combination chemotherapy regimens have shown promising results in patients with metastatic colorectal cancer. However, only very few studies have studied the effect of palliative chemotherapy in peritoneal carcinomatosis (PC) and no data are present incorporating biological therapies in the treatment of PC in colorectal cancer.METHODS: By means of merging with the regional Eindhoven Ca

Millora 2.0: Redovisning av resultat för 2018–2020

Based on repeated surveys of the vascular plant flora in 120 hectar plots in the province of Scania, southern-most Sweden, and analyses based on species-specific traits and ecological indicator values, it is concluded that significant changes have taken place 2018–2020 but that they probably mostly reflect the effects of the extremely dry and hot summer of 2018. Species richness has increased signBased on repeated surveys of the vascular plant flora in 120 hectar plots in the province of Scania, southern-most Sweden, and analyses based on species-specific traits and ecological indicator values, it is concluded that significant changes have taken place 2018–2020 but that they probably mostly reflect the effects of the extremely dry and hot summer of 2018. Species richness has increased sign

The use of Oxaliplatin or Mitomycin C in HIPEC treatment for peritoneal carcinomatosis from colorectal cancer : a comparative study

BACKGROUND: Oxaliplatin and Mitomycin C (MMC) are both suitable as intraperitoneal chemotherapy agents in HIPEC for peritoneal carcinomatosis (PC) of colorectal cancer (CRC).METHODS: Patient cohorts from two different HIPEC-centers underwent cytoreductive surgery and HIPEC with Oxaliplatin (39 patients) and MMC (56 patients), respectively. They were compared for toxicity and survival data. The ext