JavaScript lets developers provide client-side interactivity in Web applications, but because it is sequential, it can't take advantage of multicore processors. Thread-level speculation (TLS) addresses this issue by enabling the speculation of JavaScript function calls and thus exploits the parallel performance potential multicore processors provide. The authors implemented TLS in the Squirrelfish

Software process analysis and improvement relies heavily on empirical research. Empirical research requires measurement, experimentation, and modeling. However, whatever evidence is gained via empirical research is strongly context dependent. Thus, it is hard to combine results and capitalize upon them for the purpose of improvement in evolving development environments. The process simulationmodel

In paper one, we investigated how the pharmacological activation and inhibition of the glucocorticoid system affects lifespan and symptoms in a mouse model for RTT. We performed a long-term drug treatment study with the GR activator corticosterone and the GR inhibitor RU486 under which we measured the lifespan and onset of RTT-like symptoms of male Mecp2-null and female Mecp2 heterozygous mice in

Mitochondrial dysfunction is an important cause for neonatal liver disease. Disruption of genes encoding oxidative phosphorylation (OXPHOS) components usually causes embryonic lethality, and thus few disease models are available. We developed a mouse model for GRACILE syndrome, a neonatal mitochondrial disease with liver and kidney involvement, caused by a homozygous BCS1L mutation (232A>G). This

The national Swedish policy on alcohol has been eroded since the country joined the European Union (EU) in 1996, leading to a steep increase in the private import of alcohol. The paper investigates the impact on drinking patterns of the greater availability of alcohol among adolescents. Two cross-sectional data sets, collected in 2003 (n = 2,760) and 2005 (n = 2,031) in schools in southern Sweden,

An analysis of three experimental films by Austrian filmmaker and artist Kerstin Cmelka (b. 1974): Neurodermitis (1998), Mit mir (2000) and Et in Arcadia ego (2000).

Apolipoprotein M (apoM) is mainly associated with high-density lipoprotein in human plasma. Despite several studies suggesting apoM as an anti-atherogenic, its function is not yet fully understood. Plasma apoM was measured in normal pregnancies at four different gestational ages and in the postpartum period to investigate whether the concentration of apoM changes during pregnancy. In addition, apo

To determine nephritis outcomes in a prospective multi-ethnic/racial SLE inception cohort.

Heart rate can be extracted from the extracorporeal venous pressure signal of a dialysis machine. The results are of comparable accuracy and reliability to the ones obtained by the PPG reference signal from a pulse oximeter. Difficulties that occur during heart rate estimation were determined, and some can be overcome by a slight adjustment of blood flow rate. The described techniques, after being

When statistical linkage to a certain chromosomal region has been found, it is of interest to develop methods which quantify the accuracy with which the disease locus can be mapped. In this paper, we investigate the performance of three different types of confidence regions with asymptotically correct coverage probability as the number of pedigrees grows. Our setup is that of a saturated map of ma