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Studies of New Bioactive Fungal Metabolites

A number of bioactive natural products have by chromatographic techniques been isolated from extracts of various fungi, and their structures have been determined by spectroscopic and chemical methods. In the screening of fungal extracts for the inhibition of the binding of various ligands to CNS receptors in rat striatal membrane preparations in vitro, bioassay-guided fractionation of extracts of

Comparison Between Measured and Computed Structural Response of Some Reinforced Concrete Colums in Fire

This paper is the first result of recently commenced cooperation in structural fire engineering research between the Lund Institute of Technology, and the Fire Research Department of the Technical University of Brunswick. The goal of the project is to develop improved calculation methods based on more reliable behaviour models of concrete and steel. Fox this reason tests on columns carried out at

Studies of Electrocatalytic Reactions of NADH at Mediator Modified Electrodes and of H2O2 at Peroxidase Modified Electrodes

Popular Abstract in Swedish Många biokemiska reaktioner har höga aktiveringsenergier och utan de katalyserande enzymerna skulle de flesta ämnes- omsättningsprocesser fortskrida alldeles för långsamt för att uppehålla liv. Enzymer kallas ofta för biokatalysatorer eftersom de verkar katalytiskt, dvs påskyndar kemiska reaktioner utan att själva förändras. De finns i en enorm variation eftersom vart oThis thesis addresses: (1) studies of direct and mediated electron transfer and kinetics of peroxidases on electrodes and the development of amperometric peroxidase-based biosenors, (2) electrochemical and kinetic studies of NADH oxidation at mediator modified electrodes. The direct and mediated electron transfer of horseradish and tobacco peroxidase were investigated on graphite electrodes by us

Expression and localization of extracellular matrix proteins in rat skeletal development

Several novel matrix molecules of cartilage and bone have recently been identified and characterized. Studies of the maturation of the femoral head give clues as to the function of the novel matrix proteins. We have studied the expression and localization of two cartilage proteins: COMP, chondroadherin (CHAD), and two bone proteins: BSP and osteoadheirn (OSAD). COMP was localized throughout cartil

Characteristics of Collaboration in Product Innovation in the Regional System of Innovation of East Gothia

The focus of this article is on product innovations introduced by firms (establishments) and the collaborations they enter into with other firms and organizations in carrying out this activity. The theoretical framework combines innovation theories with the literature on regional innovation systems and the knowledge-based economy. Empirically we have investigated characteristics of collaboration a

A systematic review of research on open source software in commercial software product development

Background: The popularity of the open source software development in the last decade, has brought about an increased interest from the industry on how to use open source components, participate in the open source community, build business models around this type of software development, and learn more about open source development methodologies. Aim: The aim of this study is to review research ca

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Historical, philological and theological comments on a selection from the Revelations of St. Birgitta of Sweden in modern Swedish translation.

Factors Contributing to Detrusor Overactivity - Obstruction, Hypertrophy and Afferent Nerve Stimulation

Popular Abstract in Swedish Det är välkänt att utflödesobstruktion kan leda till förstoring av blåsan med åtföljande minskning av kontraktionskraften, något som kan påvisas både in vivo och in vitro. I arbete I undersöktes därför om det fanns regionala skillnader i blåsmuskelfunktion hos kaniner med experimentell utflödesobstruktion. Efter 2 veckors obstruktion utfördes cystometri och därefter undThe consequences of bladder outlet obstruction (BOO) with respect to detrusor hypertrophy, structural and functional changes, and obstruction-induced detrusor overactivity were investigated in vivo and in vitro utilizing various animal models. Possible pathophysiological pathways and therapeutic approaches were tested by drug treatment and the use of knockout models. Furthermore the role of estrog

Endosonography of the anal spincter in women with particular reference to obstetric sphincter tears

Popular Abstract in Swedish Bakgrund Anal inkontinens, dvs. oförmåga att kontrollera gasutsläpp eller defekation, är ett fysiskt och psykiskt invalidiserande tillstånd med inte sällan avsevärda svåra sociala konsekvenser. Gradering sker efter om inkontinensen gäller gas, lös eller fast avföring samt efter frekvens: 1g/månad, 1g/vecka eller dagligen (Wexner incontinence score). Anal inkontinens kaThe aim of this thesis was to study the endosonographic morphology of the anal sphincter in women, to establish an endosonographic sphincter defect score and to relate it to anal incontinence and anal sphincter pressure. A further aim was to determine intra-observer and inter-observer agreement in detection of endosonographic anal sphincter defects. An endosonographic anal sphincter defect classif

A wavelet analysis of solar mean magnetic field measurements

Solar mean magnetic field (SMMF) measurements from the Wilcox SolarObservatory and with SOHO/MDI are analyzed using continuous wavelettransforms, SMMF variability is found at a number of temporal scales.Detected SMMF variations with a 1-2 year period is considered to belinked to long-term variations in the internal rotation of the Sun.Intermediate SMMF oscillations with a period of 80-200 days are

Safety Concept and Design for Fire Resistance of Steel Structures

This paper is aimed at describing the principles on which are based the current concepts of fire engineering design of steel structures. The first part deals with the design methods for fire safety through the definition of heat exposure and structural models. The second part reviews the state of art in structural fire calculation methods, according to different levelsof assumption.