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Human TRPA1 is a heat sensor displaying intrinsic U-shaped thermosensitivity

Thermosensitive Transient Receptor Potential (TRP) channels are believed to respond to either cold or heat. In the case of TRP subtype A1 (TRPA1), there seems to be a species-dependent divergence in temperature sensation as non-mammalian TRPA1 is heat-sensitive whereas mammalian TRPA1 is sensitive to cold. It has been speculated but never experimentally proven that TRPA1 and other temperature-sens

Increased Permeability of the Aquaporin SoPIP2;1 by Mercury and Mutations in Loop A

Aquaporins (AQPs) also referred to as Major intrinsic proteins, regulate permeability of biological membranes for water and other uncharged small polar molecules. Plants encode more AQPs than other organisms and just one of the four AQP subfamilies in Arabidopsis thaliana, the water specific plasma membrane intrinsic proteins (PIPs), has 13 isoforms, the same number as the total AQPs encoded by th

Another way to think about psychological change : experiential vs. incremental

The traditional pre-post treatment difference reflects an incremental notion of change, where a quantity of some psychological function is added to (or subtracted from) a pretreatment quantity. This study presents a complementary, experiential notion of change. Rather than a difference, change is a feeling or experience of having changed, a feeling that one is different than before. Based on a pos

Whole cell based microcontact imprinted capacitive biosensor for the detection of Escherichia coli

In this study, a label-free, selective and sensitive microcontact imprinted capacitive biosensor was developed for the detection of Escherichia coli. The recognition of E. coli was successfully performed by this sensor prepared with the combination of microcontact imprinting method and capacitive biosensor technology. After preparation of bacterial stamps, microcontact-E. coli imprinted gold elect

Early adolescents’ motivations to defend victims in school bullying and their perceptions of student–teacher relationships : A self-determination theory approach

The aim of this study was to investigate whether various dimensions of student–teacher relationships were associated with different types of motivation to defend victims in bullying and to determine the association between these types of motivations and various bystander behaviors in bullying situations among early adolescents in Italy. Data were collected from 405 Italian adolescents who complete

Microsphere-based modeling of electro-active polymers

Elektroaktiva polymerers (EAPs) främsta egenskap är deras förmåga att kunna omvandla elektrisk energi till mekanisk energi (och vice versa). Den typ av EAPs som behandlas inom ramen för detta arbete kallas för dielektriska elastomerer och är en undergrupp av elektroniska elektroaktiva polymerer. De karakteriseras av en väldigt låg elastisk styvhet, kapabel till stora elastiska deformationer, och a

Integrity breaches in a hollow fiber nanofilter – Effects on natural organic matter and virus-like particle removal

Ultrafiltration and nanofiltration have become common methods to treat surface water for drinking water purposes. Common aims of a membrane step are removal of natural organic matter (NOM), softening or adding an extra microbiological or chemical barrier. In most cases, the membrane is considered a good disinfection step; commonly the viral removal is at least 4–log. To ensure a working disinfecti

An atp binding cassette transporter mediates the uptake of α-(1,6)-linked dietary oligosaccharides in bifidobacterium and correlates with competitive growth on these substrates

The molecular details and impact of oligosaccharide uptake by distinct human gut microbiota (HGM) are currently not well understood. Non-digestible dietary galacto- and gluco-α-(1,6)-oligosaccharides from legumes and starch, respectively, are preferentially fermented by mainly bifidobacteria and lactobacilli in the human gut. Here we show that the solute binding protein (BlG16BP) associated with a

Screening of infants at eight months for atypical development in primary health care in southern Sweden

Screening studies of a population in primary health care are sparsely reported. The aim was to describe observed atypical behaviours that may be associated with autism spectrum conditions, in a population (n = 4329) of infants at eight months. Observations were performed by paediatric nurses. An observational instrument, named SEEK developed for child health care, was used focusing on social inter

A grammar sketch of Kalamang with a focus on phonetics and phonology

Kalamang is Papuan language spoken by 150 people in the east of Indonesia. The language is threatened with extinction. This thesis treats mainly phonetics and phonology, but also gives an overview over parts of Kalamang grammar. Pronouns, demonstratives, nominal morphology and some basic syntax are discussed, among other things. The thesis also includes a word list with 700 Kalamang lexemes, and a

Skördarne / Dagens stunder : jämte Disa och Hoppet. Av Johan Gabriel Oxenstierna

Moderniserad (dvs. inte textkritisk) utgåva av Johan Gabriel Oxenstiernas främsta dikter. Utförliga noter som förklarar språkliga ting såväl som referenser till kontexten, anspelningar på äldre litteratur och liknande. Utgiven i Svenska akademiens klassikerserie. Med förord av Horace Engdahl.Modernized (i.e. NOT critical) edition of the major poems of Johan Gabriel Oxenstierna. Extensive notes explaining linguistic difficulties in the text as well as information on context, literary allusions etc. In the Swedish Academy's book series Swedish Classics, with a preface by academy member Horace Engdahl.

A randomized comparison between league tables and funnel plots as an aid to health care decision-making

Objective Comparison of provider performance is commonly used to inform health care decision-making. Little attention has been paid to how data presentations influence decisions. This study analyzes differences in suggested actions by decision-makers informed by league tables or funnel plots.Design Decision-makers were invited to a survey and randomized to compare hospital performance using either

Krigets sociologi: : Analyser av krigsvåld, koncentrationsläger, offerskap och försoning

I tidigare forskning om krig presenteras ofta ensidiga bilder av fenomenen krigsvåld, offerskap och försoning. Denna bok utgår från berättelser av överlevande efter kriget i Bosnien under 1990-talet. Syftet är att analysera hur de intervjuade beskriver dessa fenomen samt vilka diskursiva mönster som framträder i konstruktionen av begreppen ”offer” och ”förövare”. Mina frågeställningar är: Hur beskThis book analyzes verbally depicted experiences of survivors from the war in Bosnia and Herzegovina. One purpose to describe how the actors portray the social phenomenon of “war violence” “victimhood” and “reconciliation”, and the second aim is to analyze discursive patterns that emerges in the creation of the terms “victim” and “perpetrator”. My research questions are: (1) How do the interviewee

Process contributions of Australian ecosystems to interannual variations in the carbon cycle

New evidence is emerging that semi-arid ecosystems dominate interannual variability (IAV) of the global carbon cycle, largely via fluctuating water availability associated with El Niño/Southern Oscillation. Recent evidence from global terrestrial biosphere modelling and satellite-based inversion of atmospheric CO2 point to a large role of Australian ecosystems in global carbon cycle variability, i

Variability in the sensitivity among model simulations of permafrost and carbon dynamics in the permafrost region between 1960 and 2009

A significant portion of the large amount of carbon (C) currently stored in soils of the permafrost region in the Northern Hemisphere has the potential to be emitted as the greenhouse gases CO2 and CH4 under a warmer climate. In this study we evaluated the variability in the sensitivity of permafrost and C in recent decades among land surface model simulations over the permafrost region between 19

Key knowledge and data gaps in modelling the influence of CO2 concentration on the terrestrial carbon sink

Primary productivity of terrestrial vegetation is expected to increase under the influence of increasing atmospheric carbon dioxide concentrations ([CO2]). Depending on the fate of such additionally fixed carbon, this could lead to an increase in terrestrial carbon storage, and thus a net terrestrial sink of atmospheric carbon. Such a mechanism is generally believed to be the primary global driver

Vegetation-climate feedbacks modulate rainfall patterns in Africa under future climate change

Africa has been undergoing significant changes in climate and vegetation in recent decades, and continued changes may be expected over this century. Vegetation cover and composition impose important influences on the regional climate in Africa. Climate-driven changes in vegetation structure and the distribution of forests versus savannah and grassland may feed back to climate via shifts in the sur