The displacement of an electroactive monitoring agent, i.e., polyamidoamine dendrimers encapsulated gold nanoparticles (PAMAM-Au) upon the presence of a target antibody via acoustic streaming has been studied. Acoustic streaming has been used to improve the mass transfer and reduce the sample incubation rate, thus this study investigated its ability in enhancing the PAMAM-Au displacement efficienc

Importance The Targeted Hypothermia vs Targeted Normothermia After Out-of-Hospital Cardiac Arrest (TTM2) trial reported no difference in mortality or poor functional outcome at 6 months after out-of-hospital cardiac arrest (OHCA). This predefined exploratory analysis provides more detailed estimation of brain dysfunction for the comparison of the 2 intervention regimens.Objectives To investigate t

Today cities are the result of centuries of history and human development, accelerated during the past 100 years. Post-industrialization, modernism’s top-down city planning approach, and the prioritisation of motor vehicle design over humans resulted in more people moving to cities, more space needed to allocate new vehicles, expansion over rural areas, and exponential pollution growth. Thus, huma

The agricultural sector in northwestern Iran uses about 95 % of the region's available water resources and nearly 98 % of are aquifer water. Despite the regiońs previous richness in water resources, the supply is now quickly decreasing. The Ghorveh-Dehgolan sub-basin in northwestern Iran consists of three dams as well as three aquifers that supply water resources for agriculture, domestic uses, an

Rapid advances in genomics have opened unprecedented possibilities to explore the mutational landscapes in malignant diseases, such as B-cell acute lymphoblastic leukemia (B-ALL). This disease is manifested as a severe defect in the production of normal blood cells due to the uncontrolled expansion of transformed B-lymphocyte progenitors in the bone marrow. Even though classical genetics identifie

This review addresses outstanding questions regarding initial pharmacological management of chronic obstructive pulmonary disease (COPD). Optimizing initial treatment improves clinical outcomes in symptomatic patients, including those with low exacerbation risk. Long-acting muscarinic antagonist/long-acting β2-agonist (LAMA/LABA) dual therapy improves lung function versus LAMA or LABA monotherapy,

Current asthma therapies focus on reducing symptoms but fail to restore existing structural damage. Mesenchymal stromal cell (MSC) administration can ameliorate airway inflammation and reverse airway remodeling. However, differences in patient disease microenvironments seem to influence MSC therapeutic effects. A polymorphic CATT tetranucleotide repeat at position 794 of the human macrophage migra

Fyra manualer/riktlinjer har gåtts genom enligt internationella bästa praktik kriterier. Dessa fyra manualer/riktlinjer valdes då trafiksäkerhetsgranskning som en systematisk procedur startade i England och dess grundläggande principer förfinades i Australien. Det är också av intresse hur Sveriges grannländer, Danmark och Norge har utvecklat sina egna nationella manualer.

The flavour-tagging algorithms developed by the ATLAS Collaboration and used to analyse its dataset of s=13 TeV pp collisions from Run 2 of the Large Hadron Collider are presented. These new tagging algorithms are based on recurrent and deep neural networks, and their performance is evaluated in simulated collision events. These developments yield considerable improvements over previous jet-flavou

The literature on sustainability transitions increasingly recognizes that sectoral structures transcending national boundaries can both hinder and promote sustainability transitions. Yet there is only limited evidence on the roles of global actors in transforming entrenched socio-technical structures directly at the global scale. To explore the mechanisms of agency at the global scale, we develop

This paper presents a measurement of fiducial and differential cross-sections for W+W- production in proton–proton collisions at s=13 TeV with the ATLAS experiment at the Large Hadron Collider using a dataset corresponding to an integrated luminosity of 139 fb - 1 . Events with exactly one electron, one muon and no hadronic jets are studied. The fiducial region in which the measurements are perfor

Marine biodiversity increased markedly during the Ordovician Period (~487–443 million years ago). Some intervals within the Ordovician were associated with unusually rapid and prominent rises in taxonomic richness, the reasons for which remain debated. Links between increased oxygenation and biodiversification have been proposed, although supporting marine oxygen proxy data are limited. Here we pr

As the climate on earth deteriorates, actions are carried out within Europe to limit the amount of hazardous emissions to lower the environmental consequences due to greenhouse gases. A significant proportion of the emissions can be linked to the construction sector and its use of virgin resources. An area with great development potential within the construction sector is linked to its management

Understanding how the design of high-pressure homogenizer valves influence pressure losses in the device is of general interest for performance optimizing, and of special importance for developing correlations for predicting gap heights and gap velocities. The traditionally used correlation is from 1975 and based on a limited experimental dataset on gaps that are longer and often of lower capacity

The discussion on the Anthropocene has increased the urgency to promote a sustainable society, considering the planetary boundaries, population growth and resource scarcity. Thus, the United Nations created the 2030 Agenda for Sustainable Development to address this challenge, including 17 Sustainable Development Goals (SDGs) and 169 SDG targets. In this context, the energy sector is one of the ma

Introduction: The Bogong moth Agrotis infusa is well known for its remarkable annual round-trip migration from its breeding grounds across eastern and southern Australia to its aestivation sites in the Australian Alps, to which it provides an important annual influx of nutrients. Over recent years, we have benefited from a growing understanding of the navigational abilities of the Bogong moth. Mea

Industrial catalysts are complex materials systems operating in harsh environments. The active parts of the catalysts are nanoparticles that expose different facets with different surface orientations at which the catalytic reactions occur. However, these facets are close to impossible to study in detail under industrially relevant operating conditions. Instead, simpler model systems, such as sing

The utilization of phase change materials (PCMs) holds tremendous potential of heat storage domain. The PCM's refractory at the latent heat thermal energy storage (LHTES) unit bottom hinders the heat storage efficiency, despite the significant improvement in thermal conductivity achieved through the addition of metal foam. This study employs numerical simulation to examine the impact of applying b