Objective: The present study addresses the problem of estimating the respiratory rate from the mor- phological ECG variations in the presence of atrial fibrilla- tory waves (f-waves). The significance of performing f-wave suppression before respiratory rate estimation is investi- gated. Methods: The performance of a novel approach to ECG-derived respiration, named “slope range” (SR) and de- signed

The Multi-Blade is a Boron-10-based neutron detector designed for neutron reflectometers and developed for the two instruments (Estia and FREIA) planned for the European Spallation Source in Sweden. A demonstrator has been installed at the AMOR reflectometer at the Paul Scherrer Institut (PSI - Switzerland). AMOR exploits the Selene guide concept and can be considered a scaled-down demonstrator of

BACKGROUND: Compared to the general population, patients with alcohol and drug addiction have an increased risk of additional hazardous lifestyles and suffer from more chronic diseases, adding to their already significantly higher morbidity and mortality. The objective of this study was to test the efficacy of the Very Integrated Program (VIP) on treatment and health outcomes for patients diagnose

This paper considers a simple model where a social planner can influence the spread-intensity of an infection wave, and, consequently, also the economic activity and population health, through a single parameter. Population health is assumed to only be negatively affected when the number of simultaneously infected exceeds health care capacity. The main finding is that if (i) the planner attaches a

Background: Humans exist in mutualistic balance with a large range of microbiota. Illness and hospitalization can disturb this balance and contribute to hospital-acquired infections (HAIs), which occur most often in critically ill patients. The use of medical devices such as central venous catheters (CVCs) and endotracheal tubes (ETTs) is essential in the care of critically ill patients. At the sa

BACKGROUND: Critically ill newborn infants undergo a variety of painful procedures or experience a variety of painful conditions during their early life in the neonatal unit. In the critically ill paediatric and neonatal population, clonidine is prescribed as an adjunct to opioids or benzodiazepines aiming to reduce the doses of these drugs that are required for analgesia or sedation, or to facili

Cell division is essential for all life forms. In bacteria, this fundamental process is precisely orchestrated by a protein, FtsZ, the ancestral homolog of eukaroytic tubulin. On the onset of division, at the division site, FtsZ assembles into a cytoskeleton structure - the Z ring - that recruits other division proteins and constricts the membrane together with cell wall synthesizing machinery, ev

Anti-LGI-1 encephalitis is a type of autoimmune encephalopathy, where antibodies react against the cell surface protein leucine-rich glioma inactivated protein 1 (LGI-1). It presents with a subacute confusion, changes in behaviour, short-term memory deficits and seizures. A piloerectile semiology is common, which has been described as reflecting insular ictal activity. Patients may have temporal l

Cerebrospinal fluid (CSF) p-tau181 (tau phosphorylated at threonine 181) is an established biomarker of Alzheimer’s disease (AD), reflecting abnormal tau metabolism in the brain. Here we investigate the performance of CSF p-tau217 as a biomarker of AD in comparison to p-tau181. In the Swedish BioFINDER cohort (n = 194), p-tau217 shows stronger correlations with the tau positron emission tomography

The number of children who were born after their parents were diagnosed with central nervous system (CNS) tumor is increasing, but it remains largely unknown regarding the academic performance of these children. We aimed to investigate whether children of survivors with childhood or adolescent CNS tumor were associated with poor academic performance. Children of survivors of CNS tumor were identif

The anthropological sciences have long been interested in how hunter-gatherers perceive and interact with their spatial environment. The spatially flexible and dynamic modes of subsistence and residence typical of many hunter-gatherer communities have been considered to be key factors in the social organisation and ideological framing of such communities. However, close attention to spatial repres

The anthropological sciences have long been interested in how hunter-gatherers perceive and interact with their spatial environment. The spatially flexible and dynamic modes of subsistence and residence typical of many hunter-gatherer communities have been considered to be key factors in the social organisation and ideological framing of such communities. However, close attention to spatial repres

Introduction: Vectorcardiography, or 3-dimensional electrocardiography is a tool which can be used to identify subtle changes in the electrical forces of the heart, and which can be applied to atrial depolarization, ventricular depolarization and ventricular repolarization for prognostic and diagostic purposes. Methods: Kor’s regression-related and quasi orthogonal methods was used to derive vect

How did industrialisation affect land use and residential patterns in cities of the nineteenth century? We use census data and GIS mapping techniques to analyse class segregation and changes to the spatial structure using the case of Uppsala, Sweden between 1880 and 1900. We find that there was a clear concentration of business activity in the central district and in proximity to the transportatio