Objective: Although targeted approaches have become available in second- and third-line settings, platinum-based chemotherapy remains the standard first-line treatment for advanced muscle-invasive bladder cancer (MIBC). Therefore, the prediction of platinum resistance is of utmost clinical importance. Methods: In this study, we established a routine compatible method for the molecular classificati

I rapporten analyseras inkomstskatte- och fastighetsbeskattningens betydelse för reinvesteringar i energibranschen. Bl.a. görs beräkningar av skatteuttagen i en jämförande studie med beskattningen av den svenska bolagssektorn. Vidare analyseras kopplingen mellan redovisning och beskattning och uppkomna skattekrediter.

Pointing with the chin is a practice attested worldwide: it is an effective and highly recognizable device for re-orienting the attention of the addressee. For the chin point to be observed, the addressee must attend carefully to the movements of the sender’s head. This demand comes into conflict with the politeness norms of many cultures, since these often require conversationalists to avoid meet

Obstetric records of hospital births of children present in the Scanian Economic Demographic Database. The records contain information on gestational age, birthweight, and other indicators of health of the child, as well as information on maternal health.

Trots att jordbrukets näringsutsläpp till Östersjön har minskat krävs mycket mer för att uppnå de uppsatta miljömålen. Vi har utvärderat politiken som används för att minska utsläppen från de nio länder som samarbetar om restaureringen av Östersjön. Vi finner att den nuvarande politiken är otillräcklig eftersom:Många länder har inte genomfört de utlovade åtgärderna för att minska näringsutsläpp fr

Providing an in-depth and cutting-edge investigation into the rise of Asian research practices and paradigms, Mats Benner examines how this rise has been accomplished, what effects it has had, and how it has shaped universities across seven Asian countries.

This article presents the first measurement of the interaction between charm hadrons and nucleons. The two-particle momentum correlations of pD- and p¯D+ pairs are measured by the ALICE Collaboration in high-multiplicity pp collisions at s=13 TeV. The data are compatible with the Coulomb-only interaction hypothesis within (1.1-1.5)σ. The level of agreement slightly improves if an attractive nucleo

Purpose: A preoperative estimate of the risk of malignancy for intraductal papillary mucinous neoplasms (IPMN) is important. The present study carries out an external validation of the Shin score in a European multicenter cohort. Methods: An observational multicenter European study from 2010 to 2015. All consecutive patients undergoing surgery for IPMN at 35 hospitals with histological-confirmed I

Artikeln undersöker temporal styrning i den svenska asylbyråkratin genom en kvalitativ analys av tio familjers asylakter. Dessa består av över 5 000 sidors dokumentation: asylutredningsprotokoll, beslut, domar, intyg, överklaganden, inlagor, personliga brev, minnesnoteringar med mera. Studien fokuserar särskilt på Migrationsverkets beslut och de muntliga utredningar som myndighetens handläggare ha

Dimethyl sulfide (DMS) influences climate via cloud condensation nuclei (CCN) formation resulting from its oxidation products (mainly methanesulfonic acid, MSA, and sulfuric acid, H2SO4). Despite their importance, accurate prediction of MSA and H2SO4 from DMS oxidation remains challenging. With comprehensive experiments carried out in the Cosmics Leaving Outdoor Droplets (CLOUD) chamber at CERN, w

Given a connected non-negative unit form we construct an extended affine Lie algebra by giving a Chevalley basis for it. We also obtain this algebra as a quotient of an algebra defined by means of generalized Serre relations by M. Barot, D. Kussin and H. Lenzing. This is done in an analogous way to the construction of the simply-laced affine Kac–Moody algebras. Thus, we obtain a family of extended

Introduction: Cervical cancer is a major cause of mortality and morbidity. We aimed to estimate the association between sociodemographic factors and cervical neoplasia. Material and methods: In this Swedish nationwide open cohort study, 4 120 557 women aged ≥15 years at baseline were included between January 1, 2002 and December 31, 2018. The two outcomes were cervical cancer and carcinoma in situ

To increase the understanding of the role of carbide precipitates on the hydrogen embrittlement of martensiticsteels, we have performed a density functional theory study on the solution energies and energy barriers forhydrogen diffusion in orthorhombic M7C3 (M = Cr, Mn, Fe). Hydrogen can easily diffuse into the lattice andcause internal stresses or bond weakening, which may promote reduced ductili

Nästa år ska regeringen enligt klimatlagen presentera en handlingsplan för hur Sverige ska nå klimatmålen. Minst ett dussin myndigheter har bidragit med underlag. Men inte ens om samtliga förslag i dessa rapporter genomförs kommer det att räcka för att fylla det gap som har uppstått med den nya regeringens politik, skriver Klimatpolitiska rådet.

European local authorities increasingly use social media to present services and activities organized for citizens living in the particular area. Previous studies found that authority-managed social media visually depicted older adults as being active, sociable, happy, and physically capable, reflecting the normative “third age” representation. Yet few studies to date have examined how local autho

Sedan vintern 2020 har Covid-19 förändrat livet för många människor.Syftet med den aktuella studien är att undersöka hur socialarbetarespecialiserade på våld i nära relationer balanserar förväntningar ochbehov av att skydda sig gentemot infektion med förväntningar ochbehov att skydda klienter och hur detta påverkar deras diskretion.Kvalitativa intervjuer med socialarbetare, teamledare och chefer i

The enzymatic depolymerization of synthetic polyesters has become of great interest in recycling plastics. Most of the research in this area focuses on the depolymerization of polyethylene terephthalate (PET) due to its widespread use in various applications. However, the enzymatic activity on other commercial polyesters is less frequently investigated. Therefore, AkestraTM attracted our attention