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Evidence of ACL healing on MRI following ACL rupture treated with rehabilitation alone may be associated with better patient-reported outcomes : A secondary analysis from the KANON trial

Objectives Evaluate the natural course of anterior cruciate ligament (ACL) healing on MRI within 5 years of acute ACL rupture and compare 2-year and 5-year outcomes based on healing status and treatment group. Methods Secondary analysis of 120 Knee Anterior Cruciate Ligament Nonsurgical vs Surgical Treatment (KANON) trial participants randomised to rehabilitation and optional delayed ACL reconstru

A Screening Tool to Quickly Identify Movement Disorders in Patients with Inborn Errors of Metabolism

BACKGROUND: Movement disorders are frequent in patients with inborn errors of metabolism (IEMs) but poorly recognized, particularly by nonmovement disorder specialists. We propose an easy-to-use clinical screening tool to help recognize movement disorders.OBJECTIVE: The aim is to develop a user-friendly rapid screening tool for nonmovement disorder specialists to detect moderate and severe movemen

A final drive device for torque vectoring in small racing cars

En slutväxellåda för individuell styrning av drivhjulsmoment anpassad för små tävlingsbilar Studien visar utvecklingsprocessen för en mekanisk lösning som ger stor frihet i styrningen av drivhjulsmoment och storleksmässigt lämpar sig för små tävlingsbilar. Kärnan i lösningen är att till vardera drivande hjul koppla en slirkoppling som styrs av en hydraulisk pump. I arbetet presenteras en komplett The agility of the car can be improved by distributing the longitudinal tire forces unevenly between the wheels. The resulting yaw moment helps the car to steer in transient driving scenarios, like on a slalom course. The available grip in steady state cornering can also be increased along with stability. The goal in this project is to develop a final drive device for torque vectoring in a small r

Continuous enzymatic hydrolysis of cellulose for bioethanol production

Energi från förnybara källor står idag enbart för 13,8% av världens totala energiproduktion. Detta är ett för lågt värde om det ska vara möjligt att nå målet om en klimatneutral ekonomi senast år 2050. En möjlig lösning för att öka mängden förnybar energi är genom att processera en biprodukt som vetehalm för att producera stora mängder bioetanol. Processen inleds med att vetehalmen förbehandlas tiAs of today, renewable energy accounts for only 13.8 % of the total world energy supply. This number must increase if we want to have a climate neutral economy by 2050. One possible way to increase the renewable energy percentage is by processing and using a byproduct such as wheat straw to make bioethanol. This process involves a pretreatment of the wheat straw into a pressed and pulverized mater

High variability in tuberculosis treatment outcomes across 15 health facilities in a semi-urban area in central Ethiopia

Background: Despite reported tuberculosis (TB) treatment success rate of 86%, TB remains a leading cause of death in Ethiopia. We investigated patient and provider-specific factors associated with unfavorable treatment outcomes in Ethiopian health facilities providing TB care. Methods: Data on characteristics and treatment outcomes of patients registered for TB treatment at 15 public health facili

Tractography indicates lateralized differences between trigeminal and olfactory pathways

Odorous sensations are based on trigeminal and olfactory perceptions. Both trigeminal and olfactory stimuli generate overlapping as well as distinctive activations in the olfactory cortex including the piriform cortex. Orbitofrontal cortex (OFC), an integrative center for all senses, is directly activated in the presence of olfactory stimulations. In contrast, the thalamus, a very important midbra

Subtle Differences in Brain Architecture in Patients with Congenital Anosmia

People suffering from congenital anosmia show normal brain architecture although they do not have functional sense of smell. Some studies in this regard point to the changes in secondary olfactory cortex, orbitofrontal cortex (OFC), in terms of gray matter volume increase. However, diffusion tensor imaging has not been explored so far. We included 13 congenital anosmia subjects together with 15 co

Midbrain area and the hummingbird sign from brain MRI in progressive supranuclear palsy and idiopathic normal pressure hydrocephalus

BACKGROUND AND PURPOSE: The main radiological finding in progressive supranuclear palsy (PSP) is reduced midbrain volume. Both qualitative (e.g., hummingbird sign) and quantitative (e.g., area measurements) markers have been noted. Recent studies have shown a similar reduction also in idiopathic normal pressure hydrocephalus (iNPH). The purpose was to investigate the reliability and accuracy of th

”För mycket att göra och för lite tid” En kvalitativ intervjustudie av hur nyutexaminerade socionomer upplever sin första tid i rollen som socialsekreterare på ekonomiskt bistånd

The purpose of the study is to examine and gain an understanding of newly graduated social workers' experiences during the establishment phase as new social workers in social assistance. The study is based on a qualitative interview study where 6 newly graduated social workers on financial assistance from three different municipalities in southern Sweden have been interviewed. The results have

Glucagon-like peptide-1 receptor agonists and diabetic retinopathy : nationwide cohort and Mendelian randomization studies

BACKGROUND: The ability of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) to decrease certain microvascular events has called for the investigation of GLP-1 RAs against diabetic retinopathy (DR), but the evidence is limited. By combining data from observational and Mendelian randomization (MR) studies, we aimed to investigate whether GLP-1 RAs decrease the risk of DR.METHODS: We combined da

Olfactory disorders and consequences

Generally, three functions are assigned to the sense of smell, namely warning of potential danger, social communication, and importance for eating and drinking. These functions are also reflected in some of the complaints of patients with smell disorders: occurrence of household accidents, inability to smell other people like family members, loss of flavor perception. Still, approximately 5% of th

Large-scale randomized prostate cancer screening trials : Program performances in the european randomized screening for prostate cancer trial and the prostate, lung, colorectal and ovary cancer trial

Two large-scale randomized screening trials, the Prostate, Lung, Colorectal and Ovary (PLCO) cancer trial in the USA and the European Randomized Screening for Prostate Cancer (ERSPC) trial in Europe are currently under way, aimed at assessing whether screening reduces prostate cancer mortality. Up to the end of 1998, 102,691 men have been randomized to the intervention arm and 115,322 to the contr

Prostate Specific Antigen and Prostate Cancer in Chinese Men Undergoing Initial Prostate Biopsies Compared with Western Cohorts

Purpose We determined the characteristics of Chinese men undergoing initial prostate biopsy and evaluated the relationship between prostate specific antigen levels and prostate cancer/high grade prostate cancer detection in a large Chinese multicenter cohort. Materials and Methods This retrospective study included 13,904 urology outpatients who had undergone biopsy for the indications of prostate

Optimization of Aeration Diffuser System Design : A Simulation Study

The influence of aeration diffuser system design on electricity usage, effluent water quality, and life-cycle cost in biological wastewater treatment was investigated. A plant-wide model was implemented, and simulations were carried out with different process configurations and aeration systems. Model-aided design of new aeration diffuser systems could significantly decrease electricity usage and