Inflammation is a key feature of Parkinson’s disease (PD). In postmortem PD brains, microglial activation and enhanced major histocompatibility class II (MHCII) expression are seen concomitant to the accumulation of alpha-synuclein (α-synuclein) and loss of dopaminergic cells in the substantia nigra. Recent findings showed that α-synuclein epitopes can be presented and recognized by T-cells. PD is

The history of commercial exploitation of fish stocks is replete with instances of over-exploitation and stock collapse. Particularly in situations where little is known about a species or a particular fish stock, unregulated expansion into new fisheries may effectively wipe out a species or stock before its existence is even formally recognised or understood. Globally, there has been a strong int

Successful conservation of large carnivores can only be achieved if the side effects of carnivore presence and protection are mitigated, allowing development of sustainable agricultural practices in the local society. A core element of large carnivore management is the mitigation of carnivore attacks on livestock or dogs. However, whilst attacks may be rare, the domestic animals and their owners w

Ett landskapsperspektiv krävs för att effektivt bevara biologisk mångfald och gynna ekosystemtjänster, eftersom de bakomliggande ekologiska processerna sker på rumsliga skalor som är större än enskilda fält och gårdar. Genom att förstå dessa processer bidrar forskningsmiljön SAPES och associerade forskningsprojekt till att visa värdet av att lantbrukare samarbetar för att gemensamt gynna ekosystem

The non-Abelian Landau-Pomeranschuk-Migdal (LPM) effect arises from the quantum interference between spatially separated, inelastic radiation processes in matter. A consistent probabilistic implementation of this LPM effect is a prerequisite for extending the use of Monte Carlo (MC) event generators to the simulation of jetlike multiparticle final states in nuclear collisions. Here, we propose a l

The discovery of the Higgs boson in 2012, by the ATLAS and CMS experiments, was a success achieved with only a percent of the entire dataset foreseen for the LHC. It opened a landscape of possibilities in the study of Higgs boson properties, Electroweak Symmetry breaking and the Standard Model in general, as well as new avenues in probing new physics beyond the Standard Model. Six years after the

Single top-quark production through the exchange of a t-channel W-boson is the main electroweak production mode for top quarks at the Large Hadron Collider. I discuss a recent development in the theoretical predictions for this process, in which t-channel single-top with an additional jet is combined, at NLO accuracy, with t-channel single top production, without the introduction of a merging scal

Background: It is unclear whether there are causal associations between blood lipids, statin use and cancer risks. Under certain assumptions, Mendelian randomization analysis of a genetic marker for an exposure eliminates reverse causation and confounding. Methods: We applied Mendelian randomization analysis to genetic scores, comprising 26–41 single-nucleotide polymorphisms (SNPs), as instrumenta

This Report summarizes the proceedings of the 2013 Les Houches workshop on Physics at TeV Colliders. Session 1 dealt primarily with (1) the techniques for calculating standard model multi-leg NLO and NNLO QCD and NLO EW cross sections and (2) the comparison of those cross sections with LHC data from Run 1, and projections for future measurements in Run 2.