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EU data transfer rules and African legal realities: is data exchange for biobank research realistic?
Climate information preserved in seasonal water isotope at NEEM : Relationships with temperature, circulation and sea ice
Analyzing seasonally resolved δ18O ice core data can aid the interpretation of the climate information in ice cores, also providing insights into factors governing the δ18O signal that cannot be deciphered by investigating the annual δ18O data only. However, the seasonal isotope signal has not yet been investigated in northern Greenland, e.g., at the NEEM (North Greenland Eemian Ice Drilling) ice
Huntingtin Aggregation Impairs Autophagy, Leading to Argonaute-2 Accumulation and Global MicroRNA Dysregulation
Many neurodegenerative diseases are characterized by the presence of intracellular protein aggregates, resulting in alterations in autophagy. However, the consequences of impaired autophagy for neuronal function remain poorly understood. In this study, we used cell culture and mouse models of huntingtin protein aggregation as well as post-mortem material from patients with Huntington's disease to
Surveillance for late effects in childhood cancer survivors
Many childhood cancer survivors carry a significant risk for late morbidity and mortality, a consequence of the numerous therapeutic exposures that contribute to their cure. Focused surveillance for late therapy-related complications provides opportunities for early detection and implementation of health-preserving interventions. The substantial body of research that links therapeutic exposures us
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Geometry based channel models with cross- and autocorrelation for vehicular network simulations
Realistic network simulations are necessary to assess the performance of any communication system. In this paper, we describe an implementation of a channel model for vehicle-to-vehicle (V2V) communication in the OMNeT++/Plexe simulation environment. The model is based on previous extensive measurements in a V2V multilink highway scenario and cover line-of-sight (LOS) as well as obstructed LOS (OL
The Kobresia pygmaea ecosystem of the Tibetan highlands – Origin, functioning and degradation of the world's largest pastoral alpine ecosystem: Kobresia pastures of Tibet
With 450,000 km2 Kobresia (syn. Carex) pygmaea dominated pastures in the eastern Tibetan highlands are the world's largest pastoral alpine ecosystem forming a durable turf cover at 3000–6000 m a.s.l. Kobresia's resilience and competitiveness is based on dwarf habit, predominantly below-ground allocation of photo assimilates, mixture of seed production and clonal growth, and high genetic diversity.
Validation of a Real-Time Geometry-Based Stochastic Channel Model for Vehicular Scenarios
The performance of wireless communication systems is fundamentally determined by wireless communication channel properties. Wireless vehicular communication channels exhibit multipath propagation and non-stationary channel statistics. Methods and tools for the repeatable test of wireless communication systems and signal processing algorithms in such environments are urgently needed to enable the d
Professional blinders? The novel as an eye-opener in organizational analysis
Scholarly textbooks often follow a logic where suitable empirical cases are selected to illustrate the theoretical and analytical points that we as scholars want to make. But what would happen if we would do the opposite: build a textbook on a novel written by a novelist for such purpose and let the theories explain the actions and emotions of fictional characters? In this article, we share and reScholarly textbooks often follow a logic where suitable empirical cases are selected to illustrate the theoretical and analytical points that we as scholars want to make. But what would happen if we would do the opposite: build a textbook on a novel written by a novelist for such purpose and let the theories explain the actions and emotions of fictional characters? In this article, we share and re
Samverkan i ropet. Hur förväntas vi nå ut med vår forskning?
Disruption of a GATA1-binding motif upstream of XG/PBDX abolishes Xga expression and resolves the Xg blood group system
The Xga blood group is differentially expressed on erythrocytes from men and women. The underlying gene, PBDX, was identified in 1994, but the molecular background for Xga expression remains undefined. This gene, now designated XG, partly resides in pseudoautosomal region 1 and encodes a protein of unknown function from the X chromosome. By comparing calculated Xga allele frequencies in different
Filamentary anemometry using femtosecond laser-extended electric discharge - FALED
We demonstrate a non-contact spatiotemporally resolved comprehensive method for gas flow velocity field measurement: Filamentary Anemometry using femtosecond Laser-extended Electric Discharge (FALED). A faint thin plasma channel was generated in ambient air by focusing an 800-nm laser beam of 45 fs, which was used to ignite a pulsed electric discharge between two electrodes separated over 10 mm. T
Att göra en klassiker: om formvärldens kändisar och hur de skapas
Textbidrag till utställningsbroschyr i anslutning till den tillfälliga utställningen IKEA Hacked. Våra produkter. Dina idéer. på IKEA Museum i Älmhult som pågår mellan 28 april 2018 och 24 mars 2019.
Identification of intrinsic regulators in normal and malignant human hematopoiesis. An RNA-interference approach.
Bildandet av blodceller, hematopoesen, utgår från ett litet antal av de så kallade hematopoetiska stamceller som sitter i vår benmärg. Dessa celler har förmågan att ge upphov till alla mogna blodcellstyper av de tre hematopoetiska linjerna, samtidigt som de genom celldelning bibehåller sin egna mängd. Det har uppskattats att vi endast har några tusen hematopoetiska stamceller, men trots deras rela
Capturing seniors’ requirements for assistive robots by the use of attention cards
Abstract in UndeterminedIn this paper we describe and reflect upon a novel methodology using attention cards to facilitate communication, concentration and creativity in a user requirement workshop with seniors. Previous research indicates that seniors tend to lose focus and start cross talking during workshops, which results in broad and shallow findings. However, our findings indicate that the u
Men Are Vulnerable Too : Analysing the Self-presentation of Indian Men's Rights Activist Online Network
Review of de Groot (ed.) Uralic Essive and the Expression of Impermanent State
CFTR is involved in the regulation of glucagon secretion in human and rodent alpha cells
Glucagon is the main counterregulatory hormone in the body. Still, the mechanism involved in the regulation of glucagon secretion from pancreatic alpha cells remains elusive. Dysregulated glucagon secretion is common in patients with Cystic Fibrosis (CF) that develop CF related diabetes (CFRD). CF is caused by a mutation in the Cl- channel Cystic fibrosis transmembrane conductance regulator (CFTR)
Specific Cation Effects on SCN– in Bulk Solution and at the Air−Water Interface
The large and sparsely hydrated thiocyanate anion, SCN–, plays a prominent role in the study of specific ion effects in biological, colloid, and atmospheric chemistry due to its extreme position in the Hofmeister series. Using atomistic modeling of aqueous SCN– solutions, we provide novel insight at the molecular scale into the experimentally observed differences in ion pairing, clustering, reorie