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Spatiotemporally resolved characteristics of a gliding arc discharge in a turbulent air flow at atmospheric pressure

A gliding arc discharge was generated in a turbulent air flow at atmospheric pressure driven by a 35 kHz alternating current (AC) electric power. The spatiotemporally resolved characteristics of the gliding arc discharge, including glow-type discharges, spark-type discharges, short-cutting events and transitions among the different types of discharges, were investigated using simultaneously optica

Fetal growth and air pollution - A study on ultrasound and birth measures

Air pollution has been suggested to affect fetal growth, but more data is needed to assess the timing of exposure effects by using ultrasound measures. It is also important to study effects in low exposure areas to assess eventual thresholds of effects. The MAPSS (Maternal Air Pollution in Southern Sweden) cohort consists of linked registry data for around 48,000 pregnancies from an ultrasound dat

Development of an Osmium Redox Polymer Mediated Bioanode and Examination of Its Performance in Gluconobacter oxydans Based Microbial Fuel Cell

Gluconobacter oxydans (G. oxydans) cells together with an osmium redox polymer (ORP) [Osmium (2,2'-bipyridine)2(poly-vinylimidazole)10Cl]Cl were combined with a glassy carbon paste electrode (GCPE) to form a bioanode for a microbial fuel cell (MFC) based on G. oxydans. Although there are G.oxydans/ ORP combined bioanode in the literature, as far as it is known, this system is the first one where G

An Increased Diagnostic Sensitivity of Truncated GAD65 Autoantibodies in Type 1 Diabetes May Be Related to HLA-DQ8

N-terminally truncated (96-585) GAD65 (tGAD65) autoantibodies may better delineate type 1 diabetes than full-length GAD65 (fGAD65) autoantibodies. We aimed to compare the diagnostic sensitivity and specificity between fGAD65 and tGAD65 autoantibodies for type 1 diabetes in relation to HLA-DQ. Sera from children and adolescents with newly diagnosed type 1 diabetes (n = 654) and healthy control subj

Thyroid and islet autoantibodies predict autoimmune thyroid disease already at Type 1 diabetes diagnosis

CONTEXT: Screening of autoimmune thyroid disease in children and young adults with Type 1 diabetes is important but vary greatly between clinics.OBJECTIVE: The aim was to determine the predictive value of thyroid autoantibodies, thyroid function, islet autoantibodies, and HLA- DQ at diagnosis of Type 1 diabetes for autoimmune thyroid disease during subsequent follow-up.SETTING: 43 Paediatric Endoc

Islet autoantibodies present in association with Ljungan virus infection in bank voles (Myodes glareolus) in northern Sweden

Bank voles are known reservoirs for Puumala hantavirus and probably also for Ljungan virus (LV), a suggested candidate parechovirus in type 1 diabetes etiology and pathogenesis. The aim of this study was to determine whether wild bank voles had been exposed to LV and if exposure associated to autoantibodies against insulin (IAA), glutamic acid decarboxylase 65 (GADA), or islet autoantigen-2 (IA-2A

Incidence and prognostic significance of isolated trisomies in adult acute myeloid leukemia : A population-based study from the Swedish AML registry

OBJECTIVES AND METHODS: To ascertain the incidence/clinical implications of isolated autosomal trisomies in adult acute myeloid leukemia (AML), all such cases were retrieved from the Swedish AML Registry.RESULTS: Of the 3179 cytogenetically informative AMLs diagnosed January 1997-May 2015, 246 (7.7%) had isolated trisomies. The frequency increased by age (2.4% at age 18-60 years vs. 23% at >60 yea

Children's respiratory health in the context of housing and other social determinants in Rosengård : a cross-sectional study in an immigrant neighbourhood in Sweden

The social determinants of health form a complex and dynamic web, shaping both populationand individual health and disease. The built environment and especially human dwellingsinfluence health in many ways. Associations between factors such as dampness, mouldgrowth, heating/insulation, and crowding on the one hand and respiratory health andinfectious diseases on the other hand have been studied in

Surgeon X : antibiotikaupplysning mot en mörk fond

Platsen är London, året är 2036. Miljoner människor dör av infektioner som tidigare kunnat behandlas. Antibiotikan är inte längre verksam mot vanliga infektioner och rädslan sprider sig som ett gift i samhället. Demokratin hotas, politiker mördas och terrordåd drabbar staden. Populister spelar på folkets känslor med slagord som ”Making Britain strong again” och förnekar vetenskapliga upptäckter so

Endogenous beta-cell CART regulates insulin secretion and transcription of beta-cell genes

Impaired beta-cell function is key to the development of type 2 diabetes. Cocaine- and amphetamine-regulated transcript (CART) is an islet peptide with insulinotropic and glucagonostatic properties. Here we studied the role of endogenous CART in beta-cell function. CART silencing in INS-1 (832/13) beta-cells reduced insulin secretion and production, ATP levels and beta-cell exocytosis. This was su

Whole-genome Bisulfite Sequencing of Human Pancreatic Islets Reveals Novel Differentially Methylated Regions in Type 2 Diabetes Pathogenesis

Current knowledge about the role of epigenetics in type 2 diabetes (T2D) remains limited. Only a few studies have investigated DNA methylation of selected candidate genes or a very small fraction of genomic CpG sites in human pancreatic islets, the tissue of primary pathogenic importance for diabetes. Our aim was to characterize the whole-genome DNA methylation landscape in human pancreatic islets

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The book deals with the issue of independence and especially the way to the Creation of an independent state in the Kurdish region in Iraq. One of the main topics dealt with in the book is the challenges nationally, regionally and internationally to an independent Kurdish state created in the future. We argue that the way to independence is going through negotiations with Baghdad.