Sökresultat

Filtyp

Din sökning på "*" gav 551575 sökträffar

Morphological variation in Scandinavian populations of the diploid-tetraploid species pair Anthericum ramosum and Anthericum liliago (Anthericaceae)

Both members of the diploid-tetraploid species pair Anthericum ramosum L. and Anthericum liliago L. occur as geographically disjunct isolates on the margins of their northern range in Scandinavia. Variation in floral morphology was studied in 33 populations of A. ramosum from four geographic regions and 25 populations of A. liliago from seven regions in Scandinavia. Tepal shape was characterized w

One-Pot Synthesis of Hydrophilic Molecularly Imprinted Nanoparticles

Molecularly imprinted nanoparticles were prepared using a simple distillation precipitation polymerization method. In this work, propranolol-imprinted nanoparticles were synthesized using different cross-linkers combined with methacrylic acid (MAA) as a functional monomer in refluxing acetonitrile. Using the new synthetic method, uniform prorpanolol-imprinted nanoparticles were obtained in less th

Interhalogens (ICI/IBr3) and AgOTf in thioglycoside activation; Synthesis of bislactam analogues of ganglioside GD3

The novel promoter system IX/AgOTf (X = Cl or Br) has been evaluated in the synthesis of two bislactam analogues of GD3. We have carried out two high-yielding galactosylations in 97% and 98% yield, respectively, using ICl/AgOTf, and four sialylations in 93%, 59%, 40%, and 44% yield, using IBr/AgOTf, The choice of interhalogen (IX) is determined by the donor type used in the glycosylation. We also

Ncf1-Associated Reduced Oxidative Burst Promotes IL-33R+ T Cell-Mediated Adjuvant-Free Arthritis in Mice.

Reactive oxygen species (ROS) are important in the immune defense against invading pathogens, but they are also key molecules in the regulation of inflammatory reactions. Low levels of ROS production due to a polymorphism in the neutrophil cytosolic factor 1 (Ncf1) gene are associated with autoimmunity and arthritis severity in mouse models induced with adjuvant. We established an adjuvant-free ar

Rapid scalable plasma processing of thin-film Li–La–Zr–O solid-state electrolytes

Solid-state electrolytes, such as lithium lanthanum zirconium oxide (LLZO), show promise as technologies for next-generation high-energy-density batteries, but commercial development has been hindered by a lack of scalable processing methods. Current fabrication methods are costly or require long annealing steps to create dense films. We report an atmospheric pressure blown-arc nitrogen plasma jet

Suppressing Charge Recombination via Cu-Induced Hole Trap in CdS Nanorods for Enhanced Hydrogen Evolution

Solar-driven hydrogen production stores renewable energy chemically but suffers from efficiency limitations due to the slow hole transport-dominated recombination, which caused by high valence band degeneracy and hole effective mass. Targeted hole trap regulation is essential to minimize these losses and enhance photocatalytic H2 evolution performance for practical applications. This study address

What Kind of Economists Do We Want? From a One-Track to a Two-Track Mind

We explore the challenges facing the current academic training of economists in small European countries such as Sweden. The monolithic focus on publishing in the top-five journals, which prioritizes methodological rigor over problem-driven research, is often a threat to social relevance and policy applicability. This limits pluralism, excludes many talented economists, and fails to prepare gradua

Pericytes orchestrate a tumor-restraining microenvironment in glioblastoma

Glioblastoma (GBM) is characterized by fast progression, infiltrative growth pattern, and a high relapse rate. A defining feature of GBM is the existence of spatially and functionally distinct cellular niches, where malignant cells engage in paracrine crosstalk with cell types comprising the tumor microenvironment. Here, we identify pericytes as the most active paracrine signaling hub within the t

A Reinforcement Learning-Based Proximal Policy Optimization Approach to Solve the Economic Dispatch Problem

This paper presents a novel approach to economic dispatch (ED) optimization in power systems through the application of Proximal Policy Optimization (PPO), an advanced reinforcement learning algorithm. The economic dispatch problem, a fundamental challenge in power system operations, involves optimizing the generation output of multiple units to minimize operational costs while satisfying load dem

Pseudo-Boolean Proof Logging for Optimal Classical Planning

We introduce lower-bound certificates for classical planning tasks, which can be used to prove the unsolvability of a task or the optimality of a plan in a way that can be verified by an independent third party. We describe a general framework for generating lower-bound certificates based on pseudo-Boolean constraints, which is agnostic to the planning algorithm used. As a case study, we show how

A deep genealogy of Japanese green nationalism from the long 19th century to the present

Employing the term “green nationalism” in the broad sense of nationalist ideologies that concern themselves with the natural environment, we trace a genealogy of green nationalist thought in Japan back to the start of the long 19th century. The changing contours of this discourse are mapped through five representative writers: Moto'ori Norinaga (1730–1801), Shigetaka Shiga (1863–1927). Testurō Wat

Protocol for isolating nuclei from human stem cell-derived grafts for single-nucleus RNA sequencing

Single-nucleus RNA sequencing enables high-resolution transcriptomic profiling of brain tissue, facilitating analysis of cell identity in models of neurodegeneration and repair. Here, we present a protocol for isolating nuclei from long-term human stem cell-derived grafts in the rat brain. We describe steps for vibratome sectioning, graft dissection, nuclear extraction, and fluorescence-activated

Towards a Multi-hazard Framework for the Design of Taller Timber Structures

Multi-hazard events, though infrequent and rare, are responsible for a substantial portion of global economic losses. This book chapter investigates the complexities of multi-hazard events and explores the design challenges and methodologies in multi-hazard risk assessment and structural resilience for wooden structures. Special attention is given to the interaction between earthquakes, fires, and

Design of Tau Aggregation Inhibitors Using Iterative Machine Learning and a Polymorph-Specific Brain-Seeded Fibril Amplification Assay

The aggregation of tau into amyloid fibrils is associated with Alzheimer’s disease (AD) and related tauopathies. Since different tauopathies are characterized by the formation of distinct tau fibril morphologies, it is important to combine the search of tau aggregation inhibitors with the development of in vitro tau aggregation assays that recapitulate aggregation as it may occur in the brain. Her

Untapped : Veloce detects calcium in the atmosphere of WASP-189b

High-resolution transmission spectroscopy has become a powerful tool for detecting atomic and ionic species in the atmospheres of ultra-hot Jupiters. In this study, we demonstrate for the first time that the Australian-built Veloce spectrograph on the 3.9-m Anglo-Australian Telescope can resolve atmospheric signatures from transiting exoplanets. We observed a single transit of the ultra-hot Jupite

Association of phospholipids with pea globulins : effect on structure and foaming properties

The presence of lipids after pea protein isolation was related to changes in protein structure and functionality. The aim of this study is to investigate the effects of the presence of lipids, specifically polar endogenous lipids (phospholipids), on pea globulins' (including legumin and vicilin) structure and functionality. Pea globulins were extracted by isoelectric precipitation from defatted an

The effect of glycerol and protein structure on chemical degradation through deamidation and isomerization

Therapeutic proteins are essential in modern medicine but are often susceptible to chemical degradation during production, transportation, and storage, which can compromise functionality and even lead to immunogenicity in patients. This study investigates how the structure of the affibody GA-Z affects its chemical stability and how glycerol stabilizes the protein against deamidation and isomerizat

Depth-Profiling Cation Location and Oxidation States of Ni Foam Electrodes in Fe/Co-Enriched Electrolytes under Alkaline Water Oxidation Conditions

This study investigates the surface transformations of nickel foam (NF) electrodes induced by Fe and Co cation incorporation from the electrolyte following activation in the oxygen evolution reaction (OER), using both ex situ time-of-flight secondary ion mass spectrometry (TOF-SIMS) and in situ near-ambient pressure X-ray photoelectron spectroscopy (NAP-XPS). Electrochemical measurements demonstra

Philanthropy and gender equality : giving to women in an era of empowerment lite

Philanthropy for gender causes is recognised as a rising yet understudied phenomenon, especially in the field of social policy. This chapter provides an overview of key interdisciplinary feminist debates on the philanthropic turn to gender equality and women's empowerment. It also presents significant trends, including funding flows towards SDG5, key actors, and geographical areas of investment, a