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Software Risk Management in the Safety-critical Medical Device Domain - Involving a User Perspective

There is a thin line between life and death. In the medical domain, risk management can be an instrument that helps the development organisations to develop safer medical devices. A medical device that fails can bring harm to both patients and medical staff. The medical device domain is a complex field where there are several characteristics contributing to the complexity. Many of the functions pe

Factors Associated with Meniscal Extrusion in Knees with or at Risk for Osteoarthritis: The Multicenter Osteoarthritis Study.

Purpose: To assess the associations of meniscal tears, knee malalignment, cartilage damage, knee effusion, and body mass index with meniscal extrusion. Materials and Methods: The Multicenter Osteoarthritis study is an observational study of individuals who have or are at risk for knee osteoarthritis (OA). The HIPAA-compliant protocol was approved by the institutional review boards of all particip

Load and lock: the molecular mechanisms of B-lymphocyte commitment.

Summary: The maturation of B-lymphoid cells from hematopoietic stem cells in the bone marrow is a complex process under control of interplay between extrinsic and intrinsic factors. In addition to serving as a model for normal cell differentiation, disturbances in this process results in immunodeficiencies and malignancies, such as leukemia and lymphoma, making the subject of high relevance for mo

Chromosome 2q12, the ADRA2B I/D polymorphism and metabolic syndrome.

OBJECTIVE: To test whether a previously hypertension-linked 23 cM region on chromosome 2 is linked to the metabolic syndrome (MetS) or its individual components, and whether a common I/D polymorphism of the adrenergic receptor 2b (ADRA2B) gene, mapping in that region, is associated with the same traits. METHODS: We conducted fine mapping of the hypertension-linked region on chromosome 2 spanning b

Arkeologiska liv lästa

A critical review of Jarl Nordbladh (ed), "Arkeologiska liv. Om att leva arkeologiskt" (Archaeological lives: on living as an archaeologist, Göteborg 1995). The book deals with the lives of six Swedish and Danish archaeologists.

SOFC Modeling from Micro- to Macroscale: Transport Processes and Chemical Reactions

The purpose of this work is to investigate the interaction between transport processes and chemical reactions, with special emphasis on modeling mass transport by the Lattice Boltzmann method (LBM) at microscale of the anode of a solid oxide fuel cell (SOFC). In order to improve the performance of an SOFC, it is important to determine the microstructural effect embedded within the physical and che