The synthesis of a new unsymmetrical PCN ligand bearing tert-butyl groups on the phosphorus atom and isopropyl groups on the nitrogen donor atom is presented. It reacts with the commercially available Ni(DME)Br2 precursor to offer the corresponding t-BuPCNi-Pr pincer nickel bromide complex 1 together with a paramagnetic species, which was characterized as a tetrahedral nickel complex. Complex 1 re

The emergence of financial institutions such as the exchanges or bourses of northern Europe in the sixteenth and the seventeenth centuries made possible the emergence of speculation in financial instruments. Speculation evolved into a game with its own logic, and the implied ethos of the speculator prioritised abstract notions and self-interest.This article investigates the relation between this e

Repair of injured peripheral nerve trunks in the hand and upper extremity still represents one of the most challenging surgical constructive problems. In adults, discriminative sensory functions of the hand do not usually recover despite use of microsurgical repair techniques. A major reason for the imperfect outcome is the pronounced functional cortical reorganizations that occur after nerve inju

The increased survival in malignant cutaneous melanoma (melanoma) is probably due to early diagnosis combined with improved treatment most recently. National health campaigns and screening programs for melanoma detection were started in Sweden several decades ago. We want to assess the influence of tumor characteristics, based on the TNM classification, and of second primary cancers on overall sur

Background: Long term β-blocker therapy after myocardial infarction (MI) reduces mortality and recurrent MI but evidence for this treatment predates contemporary acute coronary care. β-blocker treatment is a key quality of care indicator in the Swedish national quality register for acute coronary care, Riks-HIA. Between 2011 and 2015 a declining number of MI-patients discharged with a β-blocker fr

Background: Although the prevalence of kidney disease is higher in those with reduced lung function, the longitudinal relationship between low lung function and future risk of chronic kidney disease (CKD) has not been widely explored. Methods: Baseline lung function was assessed in 20,700 men and 7325 women from 1974 to 1992. Mean age was 43.4 (±6.6) and 47.5 (±7.9) for men and women respectively.

We consider the role of electric fields during metal-catalysed thermal chemical vapour deposition growth of carbon nanotubes and show that enhanced growth occurs from a negatively biased electrode. An electric field, applied externally to the growing tubes and/or generated as a result of electron emission or self-biasing, may strongly affect the carbon supply through the catalyst nanoparticle, enh

A growing number of inherited disorders causing severe and progressive neurological deficits are linked to peroxisomal dysfunction. More than 15 peroxisomal diseases with neurological manifestations and some of them with dysmorphic features are identified. The diseases are classified into three groups depending on some similarities in the pathophysiology of the diseases within each group: defectiv

Benign recurrent intrahepatic cholestasis (BRIC) is a rare disorder characterized by recurrent episodes of cholestasis without permanent liver damage. Familial and sporadic cases have been described. Based on existing evidence, both autosomal-recessive and autosomal-dominant inheritance have been considered. We describe a large Dutch pedigree with 4 patients, strongly suggesting autosomal-recessiv

Background: As part of I-O Optimise, a multinational research platform providing real-world insights into the management of lung cancers, the SCAN-LEAF study aims to describe the epidemiology, clinical care and outcomes for pts with NSCLC in Scandinavia. We report initial Tx and OS for pts with NSCLC prior to the availability of immunotherapies in Sweden. Methods: The analysis includes all adult p

We analyse the validity of a commonly used identification between structures of the virtual photon γ∗→ QQ¯ and vector meson V→ QQ¯ transitions. In the existing studies of S-wave vector-meson photoproduction in the literature, such an identification is typically performed in the light-front (LF) frame while the radial component of the meson wave function is rather postulated than computed from the

BACKGROUND: Overweight and gestational diabetes are risk factors for pregnancy complications. We hypothesized that the metabolic impact of overweight on pregnancy outcome, would be different if it was combined with a predisposition for diabetes. The aim of this study was to compare the outcome of pregnancies in women with diabetes diagnosed later in life, to the outcome of pregnancies of women who

Lung cancer accounts for 1.6 million deaths per year worldwide. The majority of patients are diagnosed at advanced stages of the disease and often present with metastasis. Thus, the 5-year survival rate of lung cancer remains around 15%. Early diagnosis of lung cancer allows for better control of the disease with 5-year survival rates up to around 70%. Chest radiography is the most common techniqu