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Eye movements in visual impairment

This Special Issue describes the impact of visual impairment on visuomotor function. It includes contributions that examine gaze control in conditions associated with abnormal visual development such as amblyopia, dyslexia and neurofibromatosis as well as disorders associated with field loss later in life, such as macular degeneration and stroke. Specifically, the papers address both gaze holding

Argonaute, Vault, and Ribosomal Proteins Targeted by Autoantibodies in Systemic Lupus Erythematosus

OBJECTIVE: To expand, in an unbiased manner, our knowledge of autoantigens and autoantibodies in patients with systemic lupus erythematosus (SLE) and evaluate their associations with serological and clinical variables. METHODS: Human proteome arrays (> 21,000 proteins) were screened with serum from patients with SLE (n = 12) and healthy controls (n = 6) for IgG and IgA binding. Top hits were valid

The servitization of game meat: recreational hunting in-between wildlife care and holistic tourist experiences

Background and aim The paper is based on a study of hunting tourism enterprising in Sweden. The paper demonstrates how game meat is ascribed different, sometimes conflicting values in the moral economy of commercial hunting and identifies an emerging process of servitization of the game meat. Recreational hunting in Sweden can be described as embedded in two different but overlapping cultural and

A practical solution to the saturation problem in feedforward control for measurable disturbances

This paper treats the problem of control signal saturation caused by feedforward control from measurable load disturbances. An efficient feedforward compensator will often give significant peaks in the control signal at fast changes in the load disturbance. These peaks may cause the control signal to reach a saturation limit. In the paper, it is shown that the anti-windup function may cause unnece

Engineered human Diamond-Blackfan anemia disease model confirms therapeutic effects of clinically applicable lentiviral vector at single-cell resolution

Diamond-Blackfan anemia is a rare genetic bone marrow failure disorder which is usually caused by mutations in ribosomal protein genes. In the present study, we generated a traceable RPS19-deficient cell model using CRISPR-Cas9 and homology-directed repair to investigate the therapeutic effects of a clinically applicable lentiviral vector at single-cell resolution. We developed a gentle nanostraw

Skin mesenchymal niches maintain and protect AML-initiating stem cells

Leukemia cutis or leukemic cell infiltration in skin is one of the common extramedullary manifestations of acute myeloid leukemia (AML) and signifies a poorer prognosis. However, its pathogenesis and maintenance remain understudied. Here, we report massive AML cell infiltration in the skin in a transplantation-induced MLL-AF9 AML mouse model. These AML cells could regenerate AML after transplantat

Use of metal nanoparticles in agriculture. A review on the effects on plant germination

Agricultural nanotechnology has become a powerful tool to help crops and improve agricultural production in the context of a growing world population. However, its application can have some problems with the development of harvests, especially during germination. This review evaluates nanoparticles with essential (Cu, Fe, Ni and Zn) and non-essential (Ag and Ti) elements on plant germination. In g

The ‘seed-fern’ Lepidopteris mass-produced the abnormal pollen Ricciisporites during the end-Triassic biotic crisis

The end-Triassic mass extinction (ETE; ~201.6 million years ago) led to dramatic changes in terrestrial ecosystems including the extinction of several seed-plant groups. Among the most intriguing features in the vegetation signal is the dominance of the peculiar pollen, Ricciisporites tuberculatus Lundblad, across large areas of the Northern Hemisphere immediately prior to and during the ETE. The

Dysfunctional mucociliary clearance in asthma and airway remodeling – New insights into an old topic

Bronchial asthma is a heterogeneous respiratory condition characterized by chronic airway inflammation, airway hyperresponsiveness and airway structural changes (known as remodeling). The clinical symptoms can be evoked by (non)specific triggers, and their intensity varies over time. In the past, treatment was mainly focusing on symptoms’ alleviation; in contrast modern treatment strategies target

Simulating surface soil moisture on sandy beaches

A model that simulates surface moisture content on sandy beaches for aeolian transport applications is developed and integrated into the aeolian transport model AeoLiS. The moisture content of a thin surface layer (≈2 mm thickness) is computed as a function of wave runup, precipitation, evaporation, percolation, and capillary rise from the groundwater table. The groundwater table is simulated usin

Electrophysiological evidence for a Whorfian double dissociation of categorical perception across two languages

Languages vary considerably in how they group objects into categories. For example, the word taza in Spanish can refer to either cup or mug in English, whereas glass can refer to either copa or vaso – two different types of glasses –, in Spanish. It is still debated whether such language distinctions cause differences in early perceptual processing between speakers of different languages. Here, fo

Risk and outcomes of COVID-19 in patients with oxygen-dependent chronic respiratory failure– a national cohort study

Background: We aimed to evaluate cumulative occurrence and impact of COVID-19 in patients with chronic respiratory failure (CRF) treated with long-term oxygen therapy (LTOT). Material and methods: Data were obtained from the SCIFI-PEARL study on the entire Swedish population and on patients with oxygen-dependent CRF and no COVID-19 diagnosis before start of LTOT. Analyses were performed for three

Binocular vision and foraging in ducks, geese and swans (Anatidae)

Wide variation in visual field configuration across avian species is hypothesized to be driven primarily by foraging ecology and predator detection. While some studies of selected taxa have identified relationships between foraging ecology and binocular field characteristics in particular species, few have accounted for the relevance of shared ancestry. We conducted a large-scale, comparative anal

Age of acquisition in second language thinking

Debates around age effects in L2 learning have mostly centred around the domains of phonology, morphosyntax, and lexis. In this chapter, we expand the scope to conceptual and cognitive restructuring, much in line with Long’s (1990, 2013) discussion of the limits of age effects. Drawing on an extensive review of the extant literature, the current chapter examines the role that age of L2 acquisition

The man in the purple coat : Art and empire in Ilia Repin’s Reception of Volost Elders

This chapter discusses Ilia Repin’s court commission, Reception of Volost Elders by Alexander III in the Courtyard of the Petrovsky Palace in Moscow (1886). It argues that the painting reflected marginalizing discourses on the non-Russian minorities dominant at the outset of Alexander III’s rule. Repin employed a differentiating approach to rendering ethnically and religiously diverse representati

Embodying transnational shared space : Pirjo Honkasalo’s The 3 Rooms of Melancholia

The article investigates the ways in which Pirjo Honkasalo’s documentary The 3 Rooms of Melancholia (2004), examining the impact of the Russian-Chechen war on children, engenders a transnational audience through cinematic qualities, and most importantly through embodiment, producing a strongly affective resonance in the spectator. I argue that through a strategically affective approach to transnat

Egypt Ignited : How Steam Power Arrived on the Nile and Integrated Egypt into Industrial Capitalism (1820s-76)

Hur nådde fossildriven teknik Egypten på sin väg mot global dominans? Denna avhandling presenterar en socioekologisk historia av energiteknologier i förkoloniala Egyptens jordbruksproduktion (1820-talet-76). Den placerar dem i 1800-talet, början på Kapitalocenens epok; och i Egyptens fall är detta samtidigt en del av Storbritanniens fossila imperiums uppkomst. Denna avhandling behandlar hur ångmasHow did fossil-fuelled technology find its way to Egypt on its way to global dominance? This thesis presents a socioecological history of energy technologies in agrarian production in pre-colonial Egypt (1820s – 76). It situates them in the nineteenth century, understood as the beginning of the epoch of the Capitalocene; and in Egypt’s case, this is simultaneously part of the rise of Britain’s fos

Development and first results of a magnetic sample environment for polarized neutron imaging of thin metal sheets

Polarized neutron imaging brings the great advantage of analyzing bulk magnetic properties with good spatial resolution. The technique is based on the interaction of the neutron spin with magnetic samples or free magnetic fields and observing the changes to a spin-polarized neutron beam. The high sensitivity to even small magnetic fields is a benefit in obtaining magnetization information but simu