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From production planning flows to manufacturing operation management KPIs : linking ISO18828 & ISO22400 standards

International standards are playing a key role in leading and shaping the smart manufacturing landscape. The integration and consistency among different standards is therefore essential to effectively support industrial automation evolution and to ensure their applicability. This paper focuses on the ISO18828 and ISO22400 standards, related to the production planning process and manufacturing, con

The value of Stanford integrated psychosocial assessment for transplantation (SIPAT) in prediction of clinical outcomes following left ventricular assist device (LVAD) implantation

Background: The Stanford integrated psychosocial assessment for transplantation (SIPAT) is a validated psychosocial evaluation tool in the transplant population. Objective: We evaluated SIPAT in predicting post-left ventricular assist device (LVAD) outcomes, including cumulative re-admissions, driveline infections, pump malfunction, pump thrombosis, gastrointestinal bleeding, major bleeding, strok

Generalized Kakeya sets for polynomial evaluation and faster computation of fermionants

We present two new data structures for computing values of an n-variate polynomial P of degree at most d over a finite field of q elements. Assuming that d divides q- 1 , our first data structure relies on (d+ 1) n + 2 tabulated values of P to produce the value of P at any of the qn points using O(nqd2) arithmetic operations in the finite field. Assuming that s divides d and d / s divides q- 1 , o

Immunoprofiles of colorectal cancer from Lynch syndrome

Colorectal cancers associated with Lynch syndrome are characterized by defective mismatch repair, microsatellite instability, high mutation rates, and a highly immunogenic environment. These features define a subset of cancer with a favorable prognosis and high likelihood to respond to treatment with anti-programmed death 1 (PD-1)/programmed death ligand 1 (PD-L1) drugs. With the aim to define imm

Nanny care in Sweden : The inequalities of everyday doings of care

Political initiatives such as tax deductions for domestic services, including nannies, has, together with a growing au pair market paved the way for new possibilities of organizing child care in Sweden. This affects the everyday ‘local care loops’ for the upper middle-class families purchasing the services; the logistics of solving the work/family dilemma is changed through the possibility of hiri

Towards biomimics of cell membranes : Structural effect of phosphatidylinositol triphosphate (PIP3) on a lipid bilayer

Phosphoinositide (PIP) lipids are anionic phospholipids playing a fundamental role for the activity of several transmembrane and soluble proteins. Among all, phosphoinositol-3′,4′,5′-trisphosphate (PIP3) is a secondary signaling messenger that regulates the function of proteins involved in cell growth and gene transcription. The present study aims to reveal the structure of PIP-containing lipid me

SDN Access Control for the Masses

The evolution of Software-Defined Networking (SDN) has so far been predominantly geared towards defining and refining the abstractions on the forwarding and control planes. However, despite a maturing south-bound interface and a range of proposed network operating systems, the network management application layer is yet to be specified and standardized. It has currently poorly defined access contr

Thermodynamics of oxidation and reduction during the growth of metal catalyzed silicon nanowires

We have studied the thermodynamics of oxide formation, and the recovery of silicon and the metal catalysts from the dissociation of their respective oxides during the growth process of Si nanowires (NWs) under the Vapor → Liquid Droplet → Solid (VLS) mechanism. It is demonstrated that Si NWs under growth temperatures are thermodynamically unstable in any gas phase containing even a small concentra

Methanol as a fuel for internal combustion engines

Transportation of people and goods largely relies on the use of fossil hydrocarbons, contributing to global warming and problems with local air quality. There are a number of alternatives to fossil fuels that can avoid a net carbon emission and can also decrease pollutant emissions. However, many have significant difficulty in competing with fossil fuels due to either limited availability, limited

Destabilizing Domains Enable Long-Term and Inert Regulation of GDNF Expression in the Brain

Regulation of therapeutic transgene expression can increase the safety of gene therapy interventions, especially when targeting critical organs such as the brain. Although several gene expression systems have been described, none of the current systems has the required safety profile for clinical applications. Our group has previously adapted a system for novel gene regulation based on the destabi

Indiscernibility and Form : The Design of Unit C as a Critical Inquiry into the Guidelines for Historical Preservation

This article explores the intersection between the indiscernible forces of urbanisation and the materialisation of architectural form. Taking the design of architectural concept for an Accessory Dwelling Unit (ADU) at Råå in Sweden as an applied research project, the article argues that new techniques are needed to analyse interactions between artistic intentionality and indiscernible forces, and

Att instruera i idrottskontext

This article investigates language use in sports, and more specific how trainers address their young trainees in athletics, jujutsu, and gymnastics. The article focuses the instructions that the trainees receive when performing different exercises during training. The primary theoretical framework is Bernstein’s (1971 and onwards) concepts classification, framing, and a collective as opposed to an

Accelerating Radioactive Ion Beams with REX-ISOLDE

The post accelerator REX-ISOLDE is installed at the ISOLDE facility at CERN, where a broad variety of radioactive ions can be addressed. Since the end of 2001 beams at the final energy of 2.2 MeV/u are available. REX-ISOLDE uses a unique system of beam bunching and charge breeding. First a Penning trap accumulates and bunches the ions, which are delivered as a quasi-continuous beam from the ISOLDE

[Formula Presented] decay of [Formula Presented]

Information on gross [Formula Presented]-decay properties of neutron-rich noble gas isotopes [Formula Presented] was obtained at the PSB-ISOLDE facility at CERN using isobaric selectivity achieved by the combination of a plasma ion source with a cooled transfer line and subsequent mass separation. A doubly charged beam was used in the case of [Formula Presented] to suppress the corresponding multi

Actions helping expressed or anticipated needs : Patients with advanced cancer and their family caregivers’ experiences of specialist palliative home care teams

Patients with advanced cancer and family caregivers in palliative care face physical, psychological, social and existential challenges, much of the time home alone. Specialist palliative home care team services can be instrumental for sense of security in an uncertain situation. The aim of this study was to describe patients’ and family caregivers’ experiences of specialist palliative home care te

Bronchoscopic mucosal cryobiopsies as a method for studying airway disease

Background: Investigating disease mechanisms and treatment responses in obstructive airway diseases with invasive sampling are hampered by the small size and mechanical artefacts that conventional forceps biopsies suffer from. Endoscopic cryobiopsies are larger and more intact and are being increasingly used. However, the technique has not yet been explored for obtaining mucosa biopsies. Objective

Hybrid tests of contact events in air-to-air refueling

Air-to-air refueling is a vital technique for extending the range and endurance of manned or unmanned aircraft, with over 1000 refueling procedures flown per day in military operations. The hardware used for air-to-air refueling needs to be tailored to the specific aircraft and airspeeds involved, performing markedly different for permutations of tanker and receiver craft. Extensive flight testing