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We present genetIC, a new code for generating initial conditions for cosmological N-body simulations. The code allows precise, user-specified alterations to be made to arbitrary regions of the simulation (while maintaining consistency with the statistical ensemble). These "genetic modifications"allow, for example, the history, mass, or environment of a target halo to be altered in order to study t

Disease predisposing germline mutations in cancer susceptibility genes may consist of large genomic rearrangements, including deletions or duplications that are challenging, to detect and characterize using standard PCR-based mutation screening methods. Such rearrangements range from single exons up to hundreds of kilobases of sequence in size. Array-based comparative genomic hybridization (aCGH)

In 1553-1554 one Pieter Bruegel purchased a corrody in Sint-Janshuis, a retirement home for former employees of the Marquises of Bergen, where he would receive necessities of life and a place to stay until he would pass away. The paper reconstructs the early financial history of the retirement home, demonstrating how it was unable to cope with inflation, and struggled to provide for the inmates. I

Nowadays, many industries are investing a lot of resources in the development of new technologies that interpret hand gestures and use them as a communication interface between the user and the system. However, the surveillance industries have remained on the sidelines of this technological development. Instead, the joystick and the mouse are the most common devices found in control rooms. Using t

Context. Satellite galaxies experience multiple physical processes when interacting with their host halos, often leading to the quenching of star formation. In the Local Group, satellite quenching has been shown to be highly efficient, affecting nearly all satellites except the most massive ones. While recent surveys study Milky Way-analogs to assess how representative our Local Group is, the domi

The spiny dendrites of striatal projection neurons integrate synaptic inputs of different origins to regulate movement. It has long been known that these dendrites lose spines and display atrophic features in Parkinson's disease (PD), but the significance of these morphological changes has remained unknown. Some recent studies reveal a remarkable structural plasticity of striatal spines in parkins

Global warming is one of the major threats to humans and ecosystems, especially in already fragile areas like that of the Thar Desert in Rajasthan, India. People living there depend on rainwater for the every day life. This study aimed at investigating whether the there will be any influence on the existing rainwater harvesting structures in the future due to climate change and examining the adapt