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Bilateral Wilms' tumor

During a 16-year period, 49 children were treated for Wilms' tumor (WT); 7 were bilateral, 5 synchronous and 2 metachronous. The age at primary diagnosis was 6 months to 5 years (mean 2.4 years). All but 1 child received preoperative chemotherapy with tumor reduction. Unilateral nephrectomy was performed in 2 metachronous cases. In 3 synchronous WTs, the tumor was enucleated in 5 kidneys and a hem

A project effort estimation study

This paper outlines a four step effort estimation study and focuses on the first and second step. The four steps are formulated to successively introduce a more formal effort experience base. The objective of the study is to evaluate the needed formalism to improve effort estimation and to study different approaches to record and reuse experiences from effort planning in software projects. In the

Secreted Group IIA Phospholipase A2 Protects Humans Against the Group B Streptococcus: Experimental and Clinical Evidence.

Group B streptococcus (GBS) is a leading neonatal pathogen and a growing cause of invasive disease in the elderly, with clinical manifestations such as pneumonia and sepsis. Despite its clinical importance, little is known about innate immunity against GBS in humans. Here, we analyze the role of human group IIA secreted phospholipase A2 (sPLA2-IIA), a bactericidal enzyme induced during acute infla

Driving forces of phase transitions in surfactant and lipid systems

In aqueous surfactant and lipid systems, different liquid crystalline phases are formed at different temperatures and water contents. The "natural" phase sequence implies that phases with higher curvature are formed at higher water contents. On the other hand, there are exceptions to this rule, such as the monoolein/water system. In this system an anomalous transition from lamellar to reverse cubi

Sex ratio dynamics and fluctuating selection pressures in natural populations of the Trinidadian guppy, Poecilia reticulata

In many species, population sex ratios have far-reaching consequences for a wide variety of population-level and behavioural processes and can directly influence sexual selection through differential effects on male and female mating behaviour. Although sex ratios are often treated as more or less stable population characteristics, recent theoretical evidence suggests that sex ratios fluctuate und

Metacommunities: Spatial Dynamics and Ecological Communities

Assembly and dynamics in multispecies communities have long attracted the interest of ecologists. Yet, the subject has been studied from two separate paradigmatic angles. One line of thinking has focussed on local communities and competitive exclusion in situations when species’ niches overlap too much (limiting similarity), and on mechanisms that could prevent competitive exclusion and thus ensur

Time, space, and events in language and cognition : a comparative view

We propose an event-based account of the cognitive and linguistic representation of time and temporal relations. Human beings differ from nonhuman animals in entertaining and communicating elaborate detached (as opposed to cued) event representations and temporal relational schemas. We distinguish deictically based (D-time) from sequentially based (S-time) representations, identifying these with t

Basis set representation of the electron density at an atomic nucleus

In this paper a detailed investigation of the basis set convergence for the calculation of relativistic electron densities at the position of finite-sized atomic nuclei is presented. The development of Gauss-type basis sets for such electron densities is reported and the effect of different contraction schemes is studied. Results are then presented for picture-change corrected calculations based o

Genetic studies of body mass index yield new insights for obesity biology.

Obesity is heritable and predisposes to many diseases. To understand the genetic basis of obesity better, here we conduct a genome-wide association study and Metabochip meta-analysis of body mass index (BMI), a measure commonly used to define obesity and assess adiposity, in up to 339,224 individuals. This analysis identifies 97 BMI-associated loci (P < 5 × 10(-8)), 56 of which are novel. Five loc

Cancer risk in systemic lupus: An updated international multi-centre cohort study

Objective: To update estimates of cancer risk in SLE relative to the general population. Methods: A multisite international SLE cohort was linked with regional tumor registries. Standardized incidence ratios (SIRs) were calculated as the ratio of observed to expected cancers. Results: Across 30 centres, 16,409 patients were observed for 121,283 (average 7.4) person years. In total, 644 cancers occ

Transient Electromagnetic Waves in Nonlinear Media

Popular Abstract in Swedish Denna avhandling behandlar hur elektromagnetiska vågor utbreder sig i olika material. Vanligtvis antar man i elektromagnetiska problem att materialen är linjära, det vill säga om man vet att man får en viss utsignal från materialet vid en given insignal, så förväntar man sig att få två gånger så stor utsignal om man fördubblar insignalen. I avhandlingen försöker vi klarThis thesis is concerned with the propagation of transient electromagnetic waves in nonlinear media. It consists of a General Introduction and five scientific papers. The General Introduction gives a broad overview of nonlinear electromagnetic phenomena. The emphasis is on the representation of the constitutive functional modeling the material's response to electromagnetic excitation, and the met