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Syrians Abroad: The Future of Refugees and Their Return Home

The return of Syrian refugees has been a key topic in several forums and policy discussions over the last few years. Yet, the prospects for their return remain grim. The chapter is intended as a stimulus to further examination of an analytical debate, and offers a range of views on the argument that conditions in Syria are still not ripe for return. The chapter addresses Russia’s refugees policies

Why treatment efficacy on breathlessness in laboratory but not daily life trials? The importance of standardized exertion

PURPOSE OF REVIEW: Treatments for chronic breathlessness, including opioids and oxygen, have shown efficacy in the controlled laboratory setting, whereas effects have been inconsistent or absent in trials in daily life. This review discusses the lack of standardized exertion as a potential cause of false negative findings for breathlessness in daily life. RECENT FINDINGS: The level of breathlessne

Association Between Soft Drink Consumption and Mortality in 10 European Countries

Importance: Soft drinks are frequently consumed, but whether this consumption is associated with mortality risk is unknown and has been understudied in European populations to date.Objective: To examine the association between total, sugar-sweetened, and artificially sweetened soft drink consumption and subsequent total and cause-specific mortality.Design, Setting, and Participants: This populatio

The rise of the middle class : the income gap between salaried employees and workers in Sweden, ca. 1830–1940

We present the first comprehensive, long run salary information on Swedish middle-class employees before the twentieth century. Our data include, for instance, school teachers, professors, clerks, policemen and janitors in Stockholm and Sweden, ca. 1830–1940. We use the new data to compare the annual earnings of these middle-class employees with the annual earnings of farm workers, unskilled const

RIFM fragrance ingredient safety assessment, butyl 10-undecenoate, CAS Registry Number 109-42-2

Butyl 10-undecenoate was evaluated for genotoxicity, repeated dose toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity/photoallergenicity, skin sensitization, and environmental safety. Data from read-across analog methyl undec-10-enoate (CAS # 111-81-9) show that butyl 10-undecenoate is not expected to be genotoxic. Data on butyl 10-undecenoate and read-across analog methyl

Insulin and glucagon release from the isolated pancreas of foetal and newborn mice

The simultaneous release of insulin and glucagon was studied with isolated pancreas preparations from foetal and newborn mice. Glucose, alone or in combination with arginine, did not affect immunoreactive insulin (IRI) of glucagon-like immunoreactivity (GLI) release from the pancreases of 18-day-old foetal mice. However, on the first postnatal day, glucose stimulated the release of IRI and, in the

Whole-body cooling increases plasma endothelin-1 levels in women with primary Raynaud's phenomenon

To understand better the role of endothelin-1 (ET-1) in the pathogenesis of primary Raynaud's phenomenon (PRP), we investigated the basal ET-1 plasma levels and changes after whole-body cooling in healthy women and those with PRP. The study was performed as an open parallel-group comparison during the month of February. The Raynaud group included 21 female patients (mean age 45.3 years, range 21-5

Panopticon in the Urinal? : the Stockholm homo-sex Commission C. 1950–1965

This article examines the records of the so-called homo-sex commission—a part of the municipal Stockholm police force dedicated to the policing of male same-sex practices—as a case study of the role of policing in shaping historical understandings of homosexuality. Building on a series of documents left by the commission and high-ranking police officers, from memoranda describing the nature of hom

LRIG proteins regulate lipid metabolism via BMP signaling and affect the risk of type 2 diabetes

Leucine-rich repeats and immunoglobulin-like domains (LRIG) proteins have been implicated as regulators of growth factor signaling; however, the possible redundancy among mammalian LRIG1, LRIG2, and LRIG3 has hindered detailed elucidation of their physiological functions. Here, we show that Lrig-null mouse embryonic fibroblasts (MEFs) are deficient in adipogenesis and bone morphogenetic protein (B

Bioderived, chiral and stable 1-dimensional light-responsive nanostructures : Interconversion between tubules and twisted ribbons

HYPOTHESIS: Self-assembling molecular structures responding to light stimulus are appealing for applications as sensing and drug delivery. Supramolecular nanotubes have a relevant potential in nanotechnology as they can be used to encapsulate different loads like drugs, biological macromolecules, and nanomaterials. In addition, they are suitable elements for novel supracolloidal materials. Structu

Molecular advances to study the function, evolution and spectral tuning of arthropod visual opsins

Visual opsins of vertebrates and invertebrates diversified independently and converged to detect ultraviolet to long wavelengths (LW) of green or red light. In both groups, colour vision largely derives from opsin number, expression patterns and changes in amino acids interacting with the chromophore. Functional insights regarding invertebrate opsin evolution have lagged behind those for vertebrat

The Political Impact of the Sustainable Development Goals : Transforming Governance through Global Goals?

Written by an international team of over sixty experts and drawing on over three thousand scientific studies, this is the first comprehensive global assessment of the political impact of the Sustainable Development Goals, which were launched by the United Nations in 2015. It explores in detail the political steering effects of the Sustainable Development Goals on the UN system and the policies of

The Study of Global Environmental Politics : Strategies for Research and Learning

Contemporary research and teaching on global environmental politics (GEP) draw upon many approaches to understanding the ways in which states and societies respond to transboundary environmental problems (see Chapter 2). Approaches that emphasize the state (see Chapter 7) and international organizations (see Chapter 8) derive in a straightforward way from scholarly work in international relations

Simulating International Climate Negotiations in Classrooms

A simulation of the international climate negotiations was designed for more than 50 students of political science and other study programs dealing with sustainability. A key advantage of such simulations is that they are highly adaptable to groups of different sizes, academic backgrounds, or learning levels and can be used to teach a number of major concepts within the same framework. The primary

A Global Response to Climate Change: In, through, and for Cities?

Cities have been wildly successful over recent years in positioning themselves at the center of the global conversation on climate change. For example, the Intergovernmental Panel on Climate Change (IPCC) recently convened the Cities & Climate Change Conference (CitiesIPCC) in Edmonton, Alberta. The conference — hosted by a city that once advertised itself as Canada’s oil capital — brought tog

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In December 2015, more than 190 nation-states adopted the Paris Agreement at the 21st Conference of the Parties to the United Nations FrameworkConvention on Climate Change (UNFCCC). This widely celebrated event hasspurred great enthusiasm among experts concerned with the globalresponse to climate change. Since then, considerable progress has beenachieved on the international level, especially at t

Older Adults Living in Disadvantaged Areas : Protocol for a Mixed Methods Baseline Study on Homes, Quality of Life, and Participation in Transitioning Neighborhoods

BACKGROUND: Swedish policy states that older adults should be able to age safely with continued independence and lead active lives. However, this plays out differently in different Swedish municipalities depending upon degree of demographic change, globalization, and urbanization. Internationally, older adults living in disadvantaged areas have worse physical and mental health, activity restrictio