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Postural control and adaptation to threats to balance stability

Postural control is the ability to maintain equilibrium and orientation in a gravitational environment. It is dependent on feedback and feedforward mechanisms that generate appropriate corrective movement based on body-sway motion detected primarily by visual, vestibular, and proprioceptive sensory systems. Since information from the various senses is not always accurate (e.g. by disease) or avail

Displacement of a native by an alien bumblebee: lower pollinator efficiency overcome by overwhelmingly higher visitation frequency.

Biological invasions might constitute a major threat to mutualisms. Introduced pollinators might competitively displace their native counterparts, which in turn affects the pollination of native plants, if native and alien visitors differ in pollinator effectiveness. Since its invasion in 1994 into south-west Argentina, the introduced European bumblebee Bombus ruderatus has continuously increased

Lung Function as a Risk Factor for Subarachnoid Hemorrhage: A Prospective Cohort Study.

BACKGROUND AND PURPOSE: The etiology of subarachnoid hemorrhage (SAH) is poorly understood. Reduced lung function, expressed as low forced expiratory volume in 1 second (FEV(1)) and low forced vital capacity (FVC), is a predictor of cardiovascular disease, but whether reduced lung function is a risk factor for SAH is not known. The association between lung function and incidence of SAH was invest

A review of design considerations for light-duty diesel combustion systems

Practical aspects of light-duty diesel combustion system design are reviewed, with an emphasis on design considerations reported by manufacturers and engine design consultancies. The factors driving the selection of compression ratio, stroke-to-bore ratio, and various aspects of combustion chamber geometry are examined, along with the trends observed in these parameters in recently released engine

Markers of Prognosis in Neurodegenerative Dementia

Popular Abstract in Swedish De två vanligaste typerna av neurodegenerativ demenssjukdom är Alzheimer’s sjukdom och Lewy body demens. Båda sjukdomarna drabbar framförallt äldre människor och risken att insjukna ökar med stigande ålder. Detta innebär att demenssjukdom kommer att bli vanligare i samhället, eftersom vi blir allt äldre och andelen invånare >65 år blir allt större. Att drabbas av demensBackground: A prognostic marker should provide information about course and outcome of disease, e.g. predict time to a given endpoint or rate of progression due to disease in patients or subgroups of patients. Prognostic markers could be targeted to apply during the entire clinical course or just during distinct stages of the disease. Aim: The aim of this thesis is to identify, review and qualif

The three ZNT8 autoantibody variants together improve the diagnostic sensitivity of childhood and adolescent type 1 diabetes.

Aims: We tested whether autoantibodies to all three ZnT8RWQ variants, GAD65, insulinoma-associated protein 2 (IA-2), insulin and autoantibodies to islet cell cytoplasm (ICA) in combination with human leukocyte antigen (HLA) would improve the diagnostic sensitivity of childhood type 1 diabetes by detecting the children who otherwise would have been autoantibody-negative. Methods: A total of 686 pat

Moisture Conditions and Frost Resistance of Concrete in Hydraulic Structures

Med avseende på de svenska förhållandena vintertid kan frostpåverkan antas ha betydande inverkan på nedbrytningen av betong i vattenbyggnader. Både ytliga och inre skador, vilka misstänks ha orsakats av frostpåverkan, har upptäckts på betong i exempelvis vattenkraftkonstruktioner. Nämnda observationer har väckt frågor om vattenbyggnaders beständighet i ett kallt klimat. Ytligt belägna skador, vilOwing to the winter conditions in Sweden, the effects of frost action may have a considerable impact on the deterioration of concrete. Both superficial and internal damage, which are suspected to have been caused by frost action, have been found in concrete in hydraulic structures. These observations have raised questions about the long-term behaviour of hydraulic structures in cold regions. Supe

EULAR recommendations for the management of primary small and medium vessel vasculitis

Objectives: To develop European League Against Rheumatism (EULAR) recommendations for the management of small and medium vessel vasculitis. Methods: An expert group ( consisting of 10 rheumatologists, 3 nephrologists, 2 immunologists, 2 internists representing 8 European countries and the USA, a clinical epidemiologist and a representative from a drug regulatory agency) identified 10 topics for a

Skeletal muscle structural lipids improve during weight-maintenance after a very low calorie dietary intervention

Background: The objective was to investigate in a group of obese subjects the course in skeletal muscle phospholipid (SMPL) fatty acids (FA) during a 24-weeks weight maintenance program, which was preceded by a successful very low calorie dietary intervention (VLCD). Special focus was addressed to SMPL omega-3 FA, which is a lipid entity that influences insulin action. Methods: Nine obese subjects

Performance evaluation of a turbidimetric cystatin C assay on different high-throughput platforms

Objective. The goal with this study was to evaluate the analytical performance of a new cystatin C immunoassay (Tina-quant (R) a Cystatin C, Roche Diagnostics GmbH). The evaluation was carried out at four centers according to a standardized protocol. Material and methods. The Tina-quant (R) a Cystatin C is a latex particle-enhanced immunoturbidimetric assay. Roche cobas (R) 6000, MODULAR ANALYTICS

Conformity and the Demand for Environmental Goods

The existing literature on eco-labeling and green consumerism has been framed within a classical market context where price and quality are the drivers of consumer choice. However, it seems possible that consumers are also concerned about the choices made by other consumers. In fact, it is unclear that people's consumption decisions are made independently of social context. For instance, under the

Anti-TNF treatment of chronic arthritis in clinical practice. New assessment method and predictors of efficacy and tolerability.

Abstract Treatment of chronic inflammatory arthritis has undergone major changes over the past years following introduction of targeted biological therapies. Tumour necrosis factor (TNF) blocking therapy has been the most important biological treatment of chronic arthritis to date. The overall objective of this thesis was to develop a new assessment method of efficacy of biological therapy in clin

Learning from failures in emergency response: a series of empirical studies

Recent high-visibility disasters have fueled public and political awareness of the importance of managing and mitigating their consequences effectively. In response, various countries have enacted legislation that demands the evaluation of emergency responses so that lessons for improvement can be learned. A series of field and experimental studies were conducted from 2005 to 2007 to assess the ab

Regular moderate exercise during pregnancy does not have an adverse effect on the neurodevelopment of the child

AimCurrent U.S. guidelines suggest that pregnant women should exercise regularly during pregnancy, and we examined the neurodevelopment of the children whose mothers had taken that advice. MethodsThis Norwegian study included 188 children whose mothers had followed a structured exercise protocol and 148 control children whose mothers had not. Their cognitive, language and motor skills were assesse

Studies of the ABO and FORS Histo-Blood Group Systems: Focus on Flow Cytometric and Genetic Analysis

ABO is the clinically most important blood group system and its antigens are carbohydrate moieties present on the surface of the red blood cell (RBC) but also on other tissues throughout the body. The ABO gene encodes an enzyme, a glycosyltransferase (GT),that adds a terminal monosaccharide to the precursor structure, H antigen, to define the A or B antigens. Blood group O is due to a non-function

On numbers badly approximable by dyadic rationals

We consider a problem originating both from circle coverings and badly approximable numbers in the case of dyadic diophantine approximation. For the unit circle S we give an elementary proof that the set {x is an element of S : 2(n)x >= c (mod 1) n >= 0} is a fractal set whose Hausdorff dimension depends continuously on c and is constant on intervals which form a set of Lebesgue measure 1. Hence i

Simulating Spinal Border Cells and Cerebellar Granule Cells under Locomotion - A Case Study of Spinocerebellar Information Processing.

The spinocerebellar systems are essential for the brain in the performance of coordinated movements, but our knowledge about the spinocerebellar interactions is very limited. Recently, several crucial pieces of information have been acquired for the spinal border cell (SBC) component of the ventral spinocerebellar tract (VSCT), as well as the effects of SBC mossy fiber activation in granule cells