Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the gastrointestinal tract. With the advent of Imatinib, the treatment of gastrointestinal stromal tumor has been revolutionized as both the progression-free and overall survival rates have increased dramatically. Unfortunately, gastrointestinal stromal tumor patients on Imatinib do eventually fail due to resistance. Eve

Controlling the composition of ternary III-V semiconductor nanowires is of high technological importance and the current theoretical understanding is so far limited. We derive a model for the kinetically limited composition of metal-particle-seeded, ternary nanowires. The model is based on the diffusion controlled growth rate of supercritical nuclei. Applying this model to gold-seeded and self-see

As the knowledge base and importance of mitochondrial physiology to human health expands, the necessity for harmonizing the terminology concerning mitochondrial respiratory states and rates has become increasingly apparent. The chemiosmotic theory establishes the mechanism of energy transformation and coupling in oxidative phosphorylation. The unifying concept of the protonmotive force provides th

Enfaldig förklaring öfwer Lutheri lilla catechismum, stält genom spörsmåhl och swar / aff Olao Swebilio.Utgåva av Sveriges första riksnormerande katekes (1689) med inledning och noter.

Two nitrifying MBBR reactors were operated in parallel, one with PAC dosing and one without, to determine the effects of PAC dosing on nitrification and micropollutant adsorption in municipal wastewater. The removal of micropollutants was evaluated for several doses of PAC and batch experiments were performed to measure adsorption kinetics and nitrification rates. The influence of PAC on the nitri

Infection represents an evolutionary arms race between pathogen and host. Thus, scientists find that pathogenic microbes have evolved elegant strategies to manipulate or avoid our immune system, allowing them to persist within the human population. This thesis is largely focused on how bacteria regulate and exploit the type I interferon (IFN) response in infected macrophages – a processes of centr

Nitrate pollution of groundwater has increased dramatically worldwide due to increase of population and agricultural productivity. The resulting nitrate concentration in groundwater is usually a combination of various types of point and non-point pollutant sources. It is often difficult to distinguish between these sources since groundwater is formed in large and complex catchments with various na

Limited guidance is available to engineers on how people's walking speed in smoke can and should be represented in the fire safety design process of underground transportation systems, such as road and rail tunnels. To address this issue, the behaviour and movement of people in case of evacuation due to a fire in underground transportation systems has been investigated. In this paper, the relation

We present a simple microfluidic-based synthesis protocol to fabricate snowman like Janus hydrogel particles of poly(N-isopropylacrylamide) (PNIPAM) in micron length scale. Particles are synthesized by emulsifying a hydrogel solution (water (w)/oil (o)) followed by partial solvent evaporation. Solvent evaporation allows the hydrogels to concentrate within the droplet and phase separate into a mono

Objective: As digital technologies for health continue to develop, the ability to provide primary care services to patients with new symptoms will grow. In Sweden, two providers of digital primary care have expanded rapidly over the past years giving rise to a heated debate with clear policy implications. The purpose of the study is to present a descriptive review of digital primary care as curren