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Effects of naloxone on c-jun/AP-1 in MET-enkephalin- and FMRFamide-immunoreactive neurons of a gastropod snail

1. Opioid- and FMRFamide (FMRFa)-ergic systems are believed to play antagonistic behavioral roles in both higher and lower animals. In our previous experiments on a snail, behavioral choice has been demonstrated to be dependent on a balance between FMRFa and enkephalins [7]. Here, we examined if the disturbance of the balance causes changes in the activity of both systems. Opiate receptor blocker

Reproductive system of Hutchinsoniella macracantha (Cephalocarida)

Hutchinsoniella macracantha is a simultaneous hermaphrodite. The small, paired ovaries are cephalic. From each, a long oviduct runs posteriorly to the eighteenth trunk segment, where it loops forward and runs toward the sixth trunk segment. The paired, sausage-shaped testes are dorsal to the midgut in the anterior end of the abdomen. A vas deferens runs down from the anterior end of each testis to

Complex avoidance behavior and its neurochemical regulation in the land snail Cepea numerals

.1. In hot plate experiments, the pulmonate land snail Cepaea nemoralis displays a biphasic passive/active avoidance behaviour composed of retraction and subsequent searching mediated by antagonistic muscular systems. The switch, between the behaviours, is under neuronal control.2.2. Leu- and met-enkephalin, as well as FMRFamide-antiserum, attenuated the retraction response and potentiated the sea

A critical analysis of international standards for construction classification - results from the development of a new Swedish construction classification system

A new Swedish construction classification system, CoClass, is now under development. CoClass has presented two alternative classifications for review, both based on the standard for construction classification ISO 12006-2:2015. One alternative also applies the IEC CD 81346-series for reference designations which includes classification tables for systems and components with function as the basis f

A GPS-Based Methodology to Analyze Environment-Health Associations at the Trip Level : Case-Crossover Analyses of Built Environments and Walking

Environmental health studies have examined associations between context and health with individuals as statistical units. However, investigators have been unable to investigate momentary exposures, and such studies are often vulnerable to confounding from, for example, individual-level preferences. We present a Global Positioning System (GPS)-based methodology for segmenting individuals' observati

Coordinated integrin activation by actin-dependent force during T-cell migration

For a cell to move forward it must convert chemical energy into mechanical propulsion. Force produced by actin polymerization can generate traction across the plasma membrane by transmission through integrins to their ligands. However, the role this force plays in integrin activation is unknown. Here we show that integrin activity and cytoskeletal dynamics are reciprocally linked, where actin-depe

Multivariate Modelling of Energy Markets

This thesis contributes to the empirical energy finance literature and consists of three research papers. The common denominator for all papers is the multivariate modelling approach, placing the electricity market at the core and delving into its interdependencies on fundamentally related markets and factors.In the first paper, we focus on the multivariate modelling of the return series of electr

Pion light-by-light contributions to the muon g − 2

This paper contains some new results on the hadronic light-by-light contribution (HLbL) to the muon g − 2. The first part argues that we can expect large effects from disconnected diagrams in present and future calculations by lattice QCD of HLbL. The argument is based on the dominance of pseudo-scalar meson exchange. In the second part, we revisit the pion loop HLbL contribution to the muon anoma

Exploration of physical and chemical cues on retinal cell fate

Identification of the key components in the physical and chemical milieu directing donor cells into a desired phenotype is a requirement in the investigation of bioscaffolds for the advancement of cell-based therapies for retinal neurodegeneration. We explore the effect of electrospun poly-ε-caprolactone (PCL) fiber scaffold topography and functionalization and culture medium, on the behavior of m

CFD analysis on flow resistance characteristics of six-start spirally corrugated tube

Heat transfer enhancement technology has been widely used in heat exchangers. The six-start spirally corrugated tube is a novel heat transfer tube, and its flow resistance characteristics have not been studied. In this paper, the flow resistance characteristics of the six-start spirally corrugated tube are studied. Specifically, the effect of influencing factors such as geometric parameters (pitch

CFD analysis on the dynamic flow characteristics of the pilot-control globe valve

The pilot-control globe valve (PCGV) is a new kind valve with simple structures and low driving energy consumption. It can utilize the pressure difference before and after the valve to control the action of the valve core. However, systematic theoretical research and numerical analysis are deficient at present. In this paper, the mathematical model of PCGV is established and Computational Fluid Dy

Energy consumption prediction of university buildings in China and strategies for energy efficiency management

In 2007, Chinese Ministry of Education (MOE) and Ministry of Housing & Urban-Rural Development (MOHURD) carried out the Campus Resource Conservation Actions, in order to take full use of resources and to improve the energy efficiency. However, due to the large amounts of universities, the total energy consumption and the energy efficiency situation have no objective statistics. Taking modeling

Transient simulation of valve core movement of pilot-control globe valve in vertical pipelines

A novel pilot-control globe valve, which can be used in vertical pipelines with a lower driving energy consumption, is proposed. A governing equation for valve core motion is obtained through a theoretical analysis of the forces applied on the valve core. A 3D simulation of valve core motion is conducted in Fluent by using User Defined Function (UDF) to involve different spring stiffness, steady s