Background Although associated with severe clinical complications, phosphate remains a neglected ion. Additionally, phosphate balance during continuous renal replacement therapy (CRRT) is complex and multifunctional. The present retrospective study investigated the effects of phosphate-containing CRRT fluid on phosphate homeostasis. Methods We retrospectively analysed 112 patients treated with CRR

The need for a scientific formalism for product realization is the translation of a need onto a product which is developed right in time, at the right costs, and fulfills the specifications set out for the product. To achieve this, most existing methods focus on the customer, or on a key technology as the backbone of product development. In this paper, we claim that efforts must be directed toward

Purpose: Outcome after lumbar disc herniation (LDH) surgery in middle-aged patient is usually reported to fulfill the criteria for successful outcome. It is also known that women in these years have an inferior outcome compared to men. This study evaluates whether the same gender differences exist in elderly. Method: In the national Swedish register for spine surgery (SweSpine) we identified 1668

Our preliminary data show high levels of adenosine in the blood of very low birth weight (VLBW) infants, positively correlating to their prematurity (i.e. body weight class). This prompted us to look for a mechanism promoting such impressive adenosine increase. We hypothesized a correlation with oxygen challenge. In fact, it is recognized that either oxygen lack or its excess contribute to the pat

Introduction: Assistive technology is required to implement the Convention of Rights of Persons with Disabilities which asserts that all people with disabilities have the right to personal mobility and available and affordable assistive technologyAim: Investigate patients’ satisfaction with their lower-limb prosthetic or orthotic device and related service delivery in Malawi and Sierra Leone and t

Introduction: Few studies have investigated overall satisfaction with prostheses fabricated using low-cost technology. Evidence-based recommendations for prosthetic and orthotic services in low-income countries are needed in order to more effectively provide services. Detailed analysis of variables which influence patient satisfaction with assistive devices are therefore of interest to investigate

This paper presents a holistic approach to perform energy renovations of office buildings. A real case study is used to demonstrate how different software can be used to facilitate the work of architects and engineers during different design stages. Initially, the moisture safety of the building is coupled to its energy performance to define the optimum insulation level. The new interior layout is

The general principles for assessing solute and fluid transport across the peritoneum in animal models are not different from those in human studies. Animal models allow for extensive standardization of experimental conditions and also for sampling of peritoneal tissues for analysis. The present review will focus on (1) the scaling issue between various species, (2) how to measure intraperitoneal

We consider the problem of identifying structural influences of external inputs on steady-state outputs in a biological network model. We speak of a structural influence if, upon a perturbation due to a constant input, the ensuing variation of the steady-state output value has the same sign as the input (positive influence), the opposite sign (negative influence), or is zero (perfect adaptation),

This paper deals with set invariance for time delay systems. The first goal of the paper is to review the known necessary or sufficient conditions for the existence of invariant sets with respect to dynamical systems described by discrete-time delay difference equations (dDDEs). Secondly, we address the construction of invariant sets in the original state space (also called D-invariant sets) by ex

Because of its immunosuppressive properties, interleukin-10 (IL-10) is thought to play an important role in a number of human disease states, including inflammation, autoimmunity, and transplant rejection. In this study, we demonstrate that introduction of human or viral IL-10 genes into Burkitt's lymphoma cells markedly reduced their ability to grow as subcutaneous (sc) tumors in SCID mice. In vi