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Investigating the effect of lecithin on acute and second-meal postprandial glycemia and appetite sensations in healthy adults - a single blind randomised crossover study

A healthy diet has demonstrated its effectiveness in preventing globally rising lifestyle-related diseases including type 2 diabetes. Moreover, previous researches investigating polar lipids suggest that these compounds could potentially enhance metabolic variables associated with type 2 diabetes. Consequently, the present study assessed two commercial lecithin preparations, rich in polar lipids,

Performing Creative Work in Public

This chapter addresses artistic research through the concept of co-costuming in public—a material-discursive practice between humans and more-than-human materialities with co-creational potentials. The chapter documents how co-costumed entanglements cultivate the wearers’ sociomaterial relation-spatial sensitivity towards each other as well as towards other humans and more-than-human materialities

The joint effects of genetic liability and the death of close relatives on risk for major depression and alcohol use disorder in a Swedish national sample

Background. To determine whether genetic risk factors for major depression (MD) and alcohol use disorder (AUD) interact with a potent stressor – death of spouse, parent, and sibling – in predicting episodes of, respectively, MD and AUD. Methods. MD and AUD registrations were assessed from national Swedish registries. In individuals born in Sweden 1960–1970, we identified 7586, 388 459, and 34 370

CONT - a Versatile and Adaptable Luminaire Designed for Longevity

The aim of this bachelor degree project is to design a modular luminaire with a longer lifespan, in order to reduce consumption. The project aims to explore how design can contribute to sustainable development by creating a durable and adaptable lighting solution. The luminaire is versatile and can either be hung from the ceiling, mounted on the wall, or placed on a table. It can be expanded

Initial Development and Validation of Language-Based Assessments for Meaningful Change

Meningsfull förändring har diskuterats i flera studier, med den återkommande frågan om hur den skulle kunna konceptualiseras och bedömas för att identifiera vad som utgör meningsfull förändring och var den uppstår. Tidigare studier har genomfört statistiska analyser baserade på traditionella betygsskalor (d.v.s. PHQ-9) för att bedöma meningsfull förändring. Det finns inga bevis för att tidigare stMeaningful change has been discussed in multiple studies, with the recurring question of how it could be conceptualized and assessed to identify what determines meaningful change and where it occurs. Previous studies have conducted statistical analyses based on traditional rating scales (i.e., the PHQ-9) to assess meaningful change. There is no evidence to be found of previous studies attempting t

En för alla, alla för en: Identitetsledarskap kopplat till socialt stöd på arbetsplatsen

Syftet med denna studie var att undersöka om de fyra dimensionerna av identitetsledarskap (prototypikalitet, avancemang, entreprenörskap och direktörskap) predicerade olika former av socialt stöd (upplevt stöd från närmaste chef och stöd från medarbetare) samt social gemenskap på arbetsplatsen. Insamlingen av data utfördes i Sverige i form av en digital enkätundersökning som besvarades av personerThe purpose of this study was to examine if the four dimensions of identity leadership (prototypicality, advancement, entrepreneurship and impresarioship) could predict different forms of social support (perceived supervisorial support and collegial support) as well as social community in the workplace. The data was collected in Sweden through a digital survey which was answered by people who had

100 ancient genomes show repeated population turnovers in Neolithic Denmark

Major migration events in Holocene Eurasia have been characterized genetically at broad regional scales1–4. However, insights into the population dynamics in the contact zones are hampered by a lack of ancient genomic data sampled at high spatiotemporal resolution5–7. Here, to address this, we analysed shotgun-sequenced genomes from 100 skeletons spanning 7,300 years of the Mesolithic period, Neol

Risk of subsequent gliomas and meningiomas among 69,460 5-year survivors of childhood and adolescent cancer in Europe : the PanCareSurFup study

Background: Childhood cancer survivors are at risk of subsequent gliomas and meningiomas, but the risks beyond age 40 years are uncertain. We quantified these risks in the largest ever cohort. Methods: Using data from 69,460 5-year childhood cancer survivors (diagnosed 1940–2008), across Europe, standardized incidence ratios (SIRs) and cumulative incidence were calculated. Results: In total, 279 g

Population-Based Validation of the MIA and MSKCC Tools for Predicting Sentinel Lymph Node Status

Importance: Patients with melanoma are selected for sentinel lymph node biopsy (SLNB) based on their risk of a positive SLN. To improve selection, the Memorial Sloan Kettering Cancer Center (MSKCC) and Melanoma Institute Australia (MIA) developed predictive models, but the utility of these models remains to be tested. Objective: To determine the clinical utility of the MIA and MSKCC models. Design

Monkeypox virus-associated meningoencephalitis diagnosed by detection of intrathecal antibody production

Background: In the 2022 mpox-outbreak most patients presented with mild symptoms. Central nervous system (CNS) involvement has previously been described as a rare and severe complication of mpox; however, diagnostic findings in cerebrospinal fluid (CSF) analysis and neuroimaging studies have only been reported in one case previously. Case presentation: We report a previously healthy 37-year-old ma

Localization and characterisation of brown rot in two types of acetylated wood

Acetylation is a commercialised chemical wood modification technology that increases the durability of wood against microbial attack. However, the details of how acetylation protects the wood structure from fungal degradation are still unclear. In this study, we tested the hypothesis that the resistance against microbial attack depends on the localisation of acetylation within the cell wall. The m

An Enzyme with High Catalytic Proficiency Utilizes Distal Site Substrate Binding Energy to Stabilize the Closed State but at the Expense of Substrate Inhibition

Understanding the factors that underpin the enormous catalytic proficiencies of enzymes is fundamental to catalysis and enzyme design. Enzymes are, in part, able to achieve high catalytic proficiencies by utilizing the binding energy derived from nonreacting portions of the substrate. In particular, enzymes with substrates containing a nonreacting phosphodianion group coordinated in a distal site