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Nanoscale characterization of collagen structural responses to in situ loading in rat Achilles tendons

The specific viscoelastic mechanical properties of Achilles tendons are highly dependent on the structural characteristics of collagen at and between all hierarchical levels. Research has been conducted on the deformation mechanisms of positional tendons and single fibrils, but knowledge about the coupling between the whole tendon and nanoscale deformation mechanisms of more commonly injured energ

Advanced Legal Practices in the Welfare State : A Study of Displacements of the Right to Social Assistance for Undocumented Persons and Poor EU Citizens, in Three Swedish Municipalities

Abstract The aim of this three-year research project is to investigate displacements, i.e. changes in the right to housing and food according to the Swedish Social Service Act between 1982-2018, and its implications for the broader issue of social rights in the welfare state. This is done through the notion of advanced legal practices, which refer to incidents where the dominant current law is con

Cryo-EM structure supports a role of AQP7 as a junction protein

Aquaglyceroporin 7 (AQP7) facilitates glycerol flux across the plasma membrane with a critical physiological role linked to metabolism, obesity, and associated diseases. Here, we present the single-particle cryo-EM structure of AQP7 determined at 2.55 Å resolution adopting two adhering tetramers, stabilized by extracellularly exposed loops, in a configuration like that of the well-characterized in

Govindjee’s 90th birthday : a life dedicated to photosynthesis

We celebrate Govindjee, Professor Emeritus of Plant Biology, Biochemistry, and Biophysics, University of Illinois at Urbana-Champaign, on the occasion of his 90th birthday. He is renowned for his pioneering work in the discovery of the two-light reactions and two photosystems, PSI and PSII, leading to the Z-scheme of the electron transport chain; and for breakthrough advances in oxygenic photosynt

Examining Legitimacy in Government Agencies’ Crisis Communication

Governments exercise power over the public in many ways. One clear example is during societal crises when government agencies engage in purposeful strategic communication, issue restrictions and recommendations, and rely on people’s compliance to reach response objectives and meet needs in society. Here, issues of authority and legitimacy are crucial. In this study, we are interested in how this p

Scientific Language Use and Sensemaking in Concept Maps : Interaction Between Concept Systems, Scientific Concepts and Everyday Concepts

The interaction between student language use and sensemaking is an area in science learning that needs further elucidation in order to meet government standards in science education. In this study, concept mapping was used to elucidate the relationship between scientific language use and sensemaking defined as the interaction between the scientific concept system and everyday concepts in order to

Influencing consumer behavioural intentions: Reducing household water consumption

Although the topic of sustainability communication has been extensively studied since the 1970s, there remain gaps and contradictions, e.g. the effectiveness of communication strategies for influencing individual pro-environmental behaviour change. This study continues this discussion: the purpose was to identify what communication interventions are most effective for changing individual intention

PROTEIN DIVERSIFICATION: An EIT FOOD White Paper

Food systems transformation is critical for meeting our climate goals, and for ensuring individual health and food security by boosting resilience to external shocks. We face the challenge of producing enough nutritious food for our growing global population, whilst reducing our environmental impact at a time of increased competition and scarcity of resources. Protein diversification can play an i

PI3-kinase p110α mediates β1 integrin-induced Akt activation and membrane protrusion during cell attachment and initial spreading

Integrin-mediated cell adhesion activates several signaling effectors, including phosphatidylinositol 3-kinase (PI3K), a central mediator of cell motility and survival. To elucidate the molecular mechanisms of this important pathway the specific members of the PI3K family activated by different integrins have to be identified. Here, we studied the role of PI3K catalytic isoforms in β1 integrin-ind

Att Skapa Ringar på Vatten

Domedagsklockan klämtar alltjämt ljudligt för planeten. Vi står inför flera globala, nationella och lokala miljöutmaningar som kan komma att påverka framtida generationer på ödesdigra sätt. Hur individer och organisationer arbetar med dessa frågor kan vara avgörande för samhällets framtida fortlevnad. Ekonomiskt stöd till en mångfald av externa projekt kan vara ett sätt att låta gräsrötter växa tiSociety is facing numerous environmental challenges today and tomorrow. Several global, national, and regional frameworks and instruments are in place to battle the storm. The Regional Council in Scania works with environmental issues through different programs and methods. Miljövårdsfonden is one of these methods, where financial support is allocated to various external projects to further a posi

The immune microenvironment in mantle cell lymphoma : Targeted liquid and spatial proteomic analyses

The complex interplay of the tumour and immune cells affects tumour growth, progression, and response to treatment. Restorationof effective immune response forms the basis of onco-immunology, which further enabled the development of immunotherapy. Inthe era of precision medicine, pin-pointing patient biological heterogeneity especially in relation to patient-specific immunemicroenvironment is a ne

Rationale and design of BROKEN-SWEDEHEART : a registry-based, randomized, parallel, open-label multicenter trial to test pharmacological treatments for broken heart (takotsubo) syndrome

Background: Takotsubo syndrome (TS) is a life-threatening acute heart failure syndrome without any evidence-based treatment options. No treatment for TS has been examined in a randomized trial. Study design and objectives: BROKEN-SWEDEHEART is a multicenter, randomized, open-label, registry-based 2 × 2 factorial clinical trial in patients with TS designed to test whether treatment with adenosine a

Fredlig krigföring, sunt spelmissbruk och hälsosamma tobaksprodukter - om konsten att få det omöjliga att verka möjligt

Examensarbetets titel: Fredlig krigföring, sunt spelmissbruk och hälsosamma tobaksprodukter - om konsten att få det omöjliga att verka möjligt Seminariedatum: 11 januari 2023 Kurs: FEKH69, Examensarbete i redovisning på kandidatnivå, 15 högskolepoäng Författare: Maria Guth Karlsson, Gabrielle Handler, Edvin Jabeskog Handledare: Alexander Hedlund Nyckelord: Hållbarhetsrapportering, LegitimitetTitle: Peaceful warfare, a sound gambling addiction and healthy tobacco - an essay on the art of making the seemingly impossible seem possible Seminar date: 11th of January 2023 Course: FEKH69, Degree Project Bachelor level, Business Administration, 15 ECTS Credits Authors: Maria Guth Karlsson, Gabrielle Handler, Edvin Jabeskog Advisor: Alexander Hedlund Key words: Sustainability reporting, Le