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Triglyceride interesterification by lipases. 3. Alcoholysis of pure triglycerides

Lipase-catalyzed alcoholysis of triolein dissolved in ethanol or isopropanol for the formation of ethyl and isopropyl esters was investigated. Of 16 lipases screened, Amano lipase from P. fluorescens was selected for investigation of the effects of basic reaction conditions on alcoholysis yields. Ethanolysis yields were only slightly affected by water additions to immobilized lipase preparations.

Influence of solvent and water activity on kinetically controlled peptide synthesis

α-Chymotrypsin deposited on Celite was used to catalyse peptide synthesis reactions between N-protected amino acid esters and leucine amide in organic media with low water content. The influence of the solvent and the thermodynamic water activity on the reaction kinetics was studied. The substrate specificity in the reactions was shown to be a combination of the substrate specificity of the enzyme

Prevalence of dementia diagnosis not otherwise specified in eight European countries A cross-sectional cohort study

BackgroundDementia is a syndrome, with a wide range of symptoms. It is important to have a timely diagnosis during the disease course to reduce the risk of medication errors, enable future care planning for the patient and their relatives thereby optimizing quality of life (QoL). For this reason, it is important to avoid a diagnosis of dementia not otherwise specified (DNOS) and instead obtain a d

Determinants of influenza vaccination among the adult and older Italian population with chronic obstructive pulmonary disease : a secondary analysis of the multipurpose ISTAT survey on health and health care use

We analyzed seasonal flu vaccination rates among the Italian population suffering from Chronic Obstructive Pulmonary Disease (COPD) in order to identify socio-demographic and clinical determinants for vaccination. We used data from the survey "Health and health care use in Italy", which interviewed 5,935 persons (age 15 - 102 years) suffering from COPD in the period 2004-2005. For each respondent,

Organic solvent changes the chymotrypsin specificity with respect to nucleophiles

In α-chymotrypsin-catalyzed acyl-transfer reactions in water the specificity of the enzyme (the nucleophile reactivity of amino acid amides) is correlated with the substrate hydrophobicity and increases as the hydrophobicity of the side chain of the amino acid amides is increased. In a low water system (4% H2O) bulky amino acid amides are less efficient nucleophiles. The specificity of α-chymotryp

Activity and stability of horse‐liver alcohol dehydrogenase in sodium dioctylsulfosuccinate/cyclohexane reverse micelles

Horse liver alcohol dehydrogenase (EC 1.1.1.1) solubilized in sodium dioctylsulfosuccinate (AOT)/cyclohexane reverse micelles was used for the oxidation of ethanol and reduction of cyclohexanone in a coupled substrate/coenzyme recycling system. The activity of the enzyme was studied as a function of pH and water content. The enzyme was optimally active in microemulsions prepared with buffer of pH

Illusions (e74), for ehn, cl, bsn, tpt, tbn, vla, vlc

This score is a 100% recomposition of my earlier piece illusions (#74/2006). As before, this music references and is inspired by a report titled, “Demonstrations of Auditory Illusions and Tricks” by Yoshitaka Nakajima, Takayuki Sasaki & Gert ten Hoopen.This piece is based on five classes of auditory illusions that were reported by Yoshitaka Nakajima, Takayuki Sasaki, & Gert ten Hoopen.

loga, a nonlinear scale of time (e104), for tpt and tbn

#104_loga, a nonlinear scale of time, for tpt, tbn. “loga, a nonlinear scale of time” refers to the illusion of nonlinear time perception. This idea suggests that our estimation of time intervals whether on a small (milliseconds) or large (decades) scale should be logarithmic, giving us a subjective experience very different from clock or calendar. Of course, our perception of time is influenced b

Evaluating the safety benefit of retrofitting motorways section with barriers meeting a new EU standard : Comparison of observational before–after methodologies

The road safety barriers are today designed and installed in compliance with the European standards for Road Restraint Systems (EN 1317), which lays down common requirements for the testing and certification in all EU countries. The introduction of the European Union (EU) regulation for safety barriers, which is based on performance, has encouraged European road agencies to perform an upgrade of t

A review and evaluation of circular business model innovation tools

The circular economy has been heralded as a potential driver for sustainable development by business, academia, and policymakers. In a future circular economy, new business models are needed that slow, close and narrow resource loops to address key resource and climate challenges. After a phase of excitement and inspiration, an operationalization phase needs to start to ensure the best possible im

Modeling the water isotopes in Greenland precipitation 1959–2001 with the meso-scale model REMO-iso

Ice core studies have proved thed18O in Greenland precipitation to be correlated to thephase of the North Atlantic Oscillation (NAO). This subject has also been investigated inmodeling studies. However, these studies have either had severe biases in thed18O levels,or have not been designed to be compared directly with observations. In this study wenudge a meso‐scale climate model fitted with stabl