PURPOSE: We determined the prognostic factors and utility of allogeneic hematopoietic cell transplantation among children with newly diagnosed hypodiploid acute lymphoblastic leukemia (ALL) treated in contemporary clinical trials.PATIENTS AND METHODS: This retrospective study collected data on 306 patients with hypodiploid ALL who were enrolled in the protocols of 16 cooperative study groups or in

We detail here the convergence properties of a new model-independent imaging method, the Lévy expansion, that seems to play an important role in the analysis of the differential cross section of elastic hadron-hadron scattering.We demonstrate, how our earlier results concerning the Odderon effects in the differential cross-section of elastic proton-proton and proton-antiproton scattering as well as t

Background: Postural Orthostatic Tachycardia Syndrome (POTS) is a cardiovascular autonomic disorder characterized by orthostatic intolerance and high prevalence among young women. The etiology of POTS is uncertain, though autoimmunity and inflammation may play an important role. We aimed to identify novel inflammatory biomarkers associated with POTS. Methods and Results: In the Syncope Study of Un

Distributing sexual content has historically been more strictly regulated in Finland than in Denmark or Sweden. Airing Emmanuelle (1974), a French softcore erotic film by Jaeckin, on Finnish television in 1987 was shocking and front-page news. The article discusses the public reception of Emmanuelle in 1987 in the context of the commercialization of television in Finland.

During the Cold War, along with the Americanization of its popular culture, Finland was also heavily exposed to Soviet ideological influences, including in relation to notions of desirable femininity. From the late 1960s onwards, Soviet influences can be seen in Finnish public discourses on fashion and decorative femininity. Soviet ideals are also reflected in the emphasis on gender neutrality and

This article presents the key findings of a Finnish memory-work project conducted in 2012 on consumer experiences and associations related to pornography. The memory-work material points to a high degree of reflexivity in definitions of pornographic preference as well as to drastic shifts in the ubiquity of pornography from the pre-1990s ‘age of scarcity’ to the current ‘age of plenty.’ At the sam

Recently, the interest to integrate magnetic resonance imaging (MRI) in radiotherapy for prostate cancer has increased considerably. MRI can contribute in all steps of the radiotherapy workflow from diagnosis, staging, and target definition to treatment follow-up. Of particular interest is the ability of MRI to provide a wide range of functional measures. The complexity of MRI as an imaging modali

Alterations in cognitive performance have been noted in nondemented subjects with elevated accumulation of amyloid-β (Aβ) fibrils. However, it is not yet understood whether brain function is already influenced by Aβ deposition during the very earliest stages of the disease. We therefore investigated associations between [18F]Flutemetamol PET, resting-state functional connectivity, gray and white m

Objective: To investigate the antimicrobial activity of peptides derived from C-type Lectin Domain Family 3 Member A (CLEC3A), shed light on the mechanism of antimicrobial activity and assess their potential application in prevention and treatment of septic arthritis. Design: We performed immunoblot to detect CLEC3A peptides in human cartilage extracts. To investigate their antimicrobial activity,

Objective: To update and expand upon prior Osteoarthritis Research Society International (OARSI) guidelines by developing patient-focused treatment recommendations for individuals with Knee, Hip, and Polyarticular osteoarthritis (OA) that are derived from expert consensus and based on objective review of high-quality meta-analytic data. Methods: We sought evidence for 60 unique interventions. A sy

INTRODUCTION The purpose of this chapter is twofold. First, it aims to provide managers and researchers with a number of concepts and perspectives which are relevant to understanding the evolution of environmental management as a corporate function. Second, in adopting and developing a critical position toward a number of current conventions or common assumptions, it aspires to add something of va