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Transient peak in moth diversity as a response to organic farming

Few initiatives to preserve and enhance biodiversity on farmland have been as thoroughly evaluated and debated as the agri-environment schemes (AES). Yet, little is known how confounding factors co-varying with the specific AES measures may affect species responses. Here, we quantify the influence of one such factor, the time since transition to organic farming, on moth diversity patterns. We foun

Pleiotropic Mechanisms for the Glucose-Lowering Action of DPP-4 Inhibitors.

Dipeptidyl peptidase (DPP)-4 inhibition is a glucose-lowering treatment for type 2 diabetes. The classical mechanism for DPP-4 inhibitors is that they inhibit DPP-4 activity in peripheral plasma, which prevents the inactivation of the incretin hormone glucagon-like peptide (GLP)-1 in the peripheral circulation. This in turn increases circulating intact GLP-1, which results in stimulated insulin se

Prediagnostic body fat and risk of death from amyotrophic lateral sclerosis: The EPIC cohort.

OBJECTIVES: The aim of this study was to investigate for the first time the association between body fat and risk of amyotrophic lateral sclerosis (ALS) with an appropriate prospective study design. METHODS: The EPIC (European Prospective Investigation into Cancer and Nutrition) study included 518,108 individuals recruited from the general population across 10 Western European countries. At recrui

Cold Nuclear Matter Effects on J/psi Yields as a Function of Rapidity and Nuclear Geometry in d plus A Collisions at root S-NN=200 GeV

We present measurements of J/psi yields in d + Au collisions at root S-NN = 200 GeV recorded by the PHENIX experiment and compare them with yields in p + p collisions at the same energy per nucleon-nucleon collision. The measurements cover a large kinematic range in J/psi rapidity (-2.2 < y < 2.4) with high statistical precision and are compared with two theoretical models: one with nuclear shadow

Long-term Outcomes of Congenital Cytomegalovirus Infection in Sweden and the United Kingdom

Background. Congenital cytomegalovirus (CMV) is an important cause of neurological problems, particularly sensorineural hearing loss, but data on long-term sequelae and the impact of nonprimary maternal infection are limited. We report updated findings on childhood outcomes from 2 large prospective studies. Methods. Pregnant women in Malmo, Sweden, and London, United Kingdom, were included between

Towards a systems-oriented framework for analysing and evaluating emergency response

Information can be provided by studying and evaluating past emergencies and the response in connection to them. This information would then be useful in efforts directed at preventing, mitigating and/or preparing for future emergencies. However, the analysis and evaluation of emergency response operations is not an easy task, especially when the operation involves several cooperating actors (e.g.

Mosaic variation in allozyme and plastid DNA markers in the European ranges of Silene vulgaris and its partially sympatric relative S-uniflora (Caryophyllaceae)

The perennial herbs Silene vulgaris and S. uniflora are closely related, partially sympatric and interfertile, yet morphologically distinct. We used nuclear (allozyme) and plastid (polymerase chain reaction-restriction fragment length polymorphism) DNA markers to investigate whether these species have a shared history of postglacial colonization and hybridization in Europe, as inferred from large-

Computerised assistance for warfarin dosage - Effects on treatment quality

Background: Well-managed warfarin treatment with a high time in therapeutic range (TTR) corresponds to fewer bleedings or thromboembolic complications. Many small centres manage their warfarin dosing manually, with little or no knowledge of their treatment quality as measured by TTR. AuriculA is a Swedish National web-based anticoagulation dosing system. Our hypothesis was that the web based dosin

Feet on the ground: Physical support of the inner retina is a strong determinant for cell survival and structural preservation in vitro.

Purpose: The purpose of this study was to explore the importance of local physical tissue support for homeostasis in the isolated retina. Methods: Full-thickness retinal sheets were isolated from adult porcine eyes. Retinas were cultured for 5 or 10 days using the previously established explant protocol with photoreceptors positioned against the culture membrane (porous polycarbonate) or the Mülle

The association between perceived relationship discord at childbirth and parental postpartum depressive symptoms: a comparison of mothers and fathers in Sweden

Aim. To examine whether mothers' and fathers' levels of perceived relationship discord at childbirth were associated with postpartum depressive symptoms when the child was 3 months old. Another aim was to examine parents' levels of self-reported depressive symptoms. The hypothesis was that parents with high levels of perceived relationship discord have higher levels of postpartum depressive sympto

Moisture levels and drying potential of the concrete in Swedish reactor containments

The climatic conditions inside nuclear reactor containments are continuously monitored by the plant owners in order to e.g. maintain a suitable climate for the mechanical and electrical equipment. Due to the high temperatures, during operation, the concrete within the containment may act as a moisture source contributing to the humidity. To evaluate if, and to what extent, the concrete inside the

Three epigenetic information channels and their different roles in evolution

There is increasing evidence for epigenetically mediated transgenerational inheritance across taxa. However, the evolutionary implications of such alternative mechanisms of inheritance remain unclear. Herein, we show that epigenetic mechanisms can serve two fundamentally different functions in transgenerational inheritance: (i) selection-based effects, which carry adaptive information in virtue of

Gonadotropin-releasing hormone analog buserelin causes neuronal loss in rat gastrointestinal tract.

Gonadotropin-releasing hormone (GnRH) analogs are given to women undergoing in vitro fertilization. Case reports describing the development of chronic intestinal pseudo-obstruction and auto-antibodies against GnRH after such treatment suggest a strong association between intestinal dysfunction and GnRH analogs. No experimental model for studying such a relationship is currently at hand. Our main g

Near-surface silica does not increase radiative heat dissipation from plant leaves

It has been suggested that plants are able to increase radiative heat dissipation from their leaves by depositing near-surface silica, in this way increasing emissivity of infrared radiation and lowering leaf temperature. In order to test this theory, we have compared emissivity and radiative dissipation over the mid-infrared range 2.5–22.3 lm of leaves of plants that accumulate silica and plants

Isotope labeled internal standards (ILIS) as a basis for quality control in clinical studies using plasma samples

For clinical proteomic studies the availability of high quality biofluid samples such as human blood plasma are extremely important. In this study we have investigated the stability of human plasma samples by spiking stable isotope-labeled peptides into the plasma and monitoring their degradation under different storage conditions. FPA-1, C4A and C3f were synthesized with isotopically labeled amin

Dual-gate induced InP nanowire diode

Semiconductor devices are heavily dependent on dopant incorporation in order to control the electrical properties. In this paper we investigate the possibility of using gates wrapped around a nanowire (NW) channel as a way of tuning the Fermi level position, in certain cases removing the need for dopants and providing a more dynamical way of setting the device properties. InP NW devices with omega

Gestational Age at Birth and Risk of Gastric Acid-Related Disorders in Young Adulthood

PURPOSE: Preterm birth is associated with gastric acid-related disorders in infancy, but no investigators have examined this association beyond early childhood. We used antisecretory medication data to explore whether preterm birth is associated with gastric acid-related disorders in young adulthood. METHODS: We conducted a national cohort study of 626,811 individuals born in Sweden in 1973 to 197