In order to obtain quantitative information of the effects of rate dependent plasticity on crack growth initiation, a strip yield (Dugdale) model for small-scale yielding is developed. The adopted rate dependence of the flow stress is of the Perzyna type. Numerical solutions are obtained for different KI(t) functions. By adopting both a displacement-criterion and a stress-criterion for crack growt

In 2013, American poet and academic Ange Mlinko published her third volume: Marvelous Things Overheard. As in her second volume, Shoulder Season, 2010, Mlinko mingles epochs and geographies in an effort to listen to and comprehend those human voices resounding mainly from conflictual areas. There is no communication without memory. That is why the poetess embodies languages, sorrows, happy feeling

A model is established that describes stress driven diffusion, resulting in formation and growth of an expanded precipitate at the tip of a crack. The new phase is transversely isotropic. A finite element method is used and the results are compared with a simplified analytical theory. A stress criterium for formation of the precipitate is derived by direct integration of the Einstein-Smoluchowski

Ian McEwan has indulged in macabre plots whose point of interest resided in the power of imaginary over the allegedly rational reality. In novels like Atonement, Enduring Love, On Chesil Beach and Amsterdam he pointed out how approaching the world scientifically can be as misleading as doing it on the religious or literary ways. The target of my paper is to spot those common places of fanaticism a

A dedicated spectroscopic study of the β decay of 127Cd was conducted at the IGISOL facility at the University of Jyväskylä. Following high-resolution mass separation in a Penning trap, β-γ-γ coincidences were used to considerably extend the decay scheme of 127In. The β-decaying 3/2+ and 11/2- states in 127Cd have been identified with the 127Cd ground state and the 283-keV isomer. Their respective

With all the versatility in structural performance and recent progress in developing magnesium alloys, their Achilles heel remains to be degradation or corrosion property. While applications in mobility demand corrosion protection by all means, bio-medical applications of Mg alloys require well-controlled degradation rates. Meeting these requirements is only possible through the understanding of p

Geovisualisation is a knowledge-intensive art in which both providers and users need to possess a wide range of knowledge. Current syntactic approaches to presenting visualisation information lack semantics on the one hand, and on the other hand are too bespoke. Such limitations impede the transfer, interpretation, and reuse of the geovisualisation knowledge. In this paper, we propose a knowledge-

To sustain their proliferation, cancer cells become dependent on one-carbon metabolism to support purine and thymidylate synthesis. Indeed, one of the most highly upregulated enzymes during neoplastic transformation is MTHFD2, a mitochondrial methylenetetrahydrofolate dehydrogenase and cyclohydrolase involved in one-carbon metabolism. Because MTHFD2 is expressed normally only during embryonic deve

Thiopurines are a standard treatment for childhood leukemia, but like all chemotherapeutics, their use is limited by inherent or acquired resistance in patients. Recently, the nucleoside diphosphate hydrolase NUDT15 has received attention on the basis of its ability to hydrolyze the thiopurine effector metabolites 6-thio-deoxyGTP (6-thio-dGTP) and 6-thio-GTP, thereby limiting the efficacy of thiop

The highly poisonous botulinum neurotoxins, produced by the bacterium Clostridium botulinum, act on their hosts by a high-affinity association to two receptors on neuronal cell surfaces as the first step of invasion. The glycan motifs of gangliosides serve as initial coreceptors for these protein complexes, whereby a membrane protein receptor is bound. Herein we set out to characterize the carbohy

3-Methyl-1,2,3-butanetricarboxylic acid (MBTCA) is a secondary organic aerosol and can be used as a unique emission marker of biogenic emissions of monoterpenes. Seasonal variations and differences in vegetation cover around the world may lead to low atmospheric MBTCA concentrations, in many cases too low to be measured. Hence, an important tool to quantify the contribution of terrestrial vegetat

For a firm in an open source software (OSS) ecosystem, the requirements engineering (RE) process is rather multifaceted. Apart from its typical RE process, there is a competing process, external to the firm and inherent to the firm’s ecosystem. When trying to impose an agenda in competition with other firms, and aiming to align internal product planning with the ecosystem’s RE process, firms need

Context: In the Requirements Engineering (RE) process of an Open Source Software (OSS) community, an involved firm is a stakeholder among many. Conflicting agendas may create miss-alignment with the firm's internal requirements strategy. In communities with meritocratic governance or with aspects thereof, a firm has the opportunity to affect the RE process in line with their own agenda by gaining

The geophysical characteristics of the carbonate-dominated Ordovician succession is described using wire-line logging data from exploration wells located within the Swedish part of the Baltic Basin, both offshore and from the island of Gotland. The petrophysical properties and log-motifs are compared and correlated with the lithology of cores from the Hamra-10, Skåls-1 and Grötlingbo-1 wells on s

Background: Patients with first-time myocardial infarction (MI) and diabetes mellitus (DM) constitute a vulnerable subgroup of cardiovascular (CV) patients for which secondary prevention is particularly important. We investigated if patients with versus without DM differ in attaining four main lifestyle-related cardiac rehabilitation (CR) targets, one-year post-MI. Methods: This national cohort st

This article puts contemporary debates about the relationship between immigration policy and the welfare state in historical perspective. Relying on new historical data, the article examines the relationship between immigration policy and social policy in Western Europe in the late 19th and early 20th centuries, when the modern welfare state emerged. Germany already had comparably strict immigrati

Drawing on fieldwork in a multi-ethnic workplace (an industrial kitchen in Denmark), this article explores immigrants' self-directed ethnic humor in collegial relationships with Danes as it spontaneously develops and plays out in everyday work settings. Approaching ethnic humor from a symbolic interactionist perspective rather than adopting the dominant conflict approach, this article emphasizes t

Background and purpose — Patient-reported outcome (PRO) in total knee arthroplasty (TKA) patients with high body mass index (BMI) is controversial. We compared pain, function, quality of life, general health, and satisfaction among different BMI categories preoperatively and 1 year after primary TKA. Patients and methods — 4,318 patients were operated with a TKA for knee osteoarthritis in the Regi