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Corrupt or Repressive? How Political Competition Incentivizes Hybrid Regimes to Subvert Police in Distinct Ways

This article develops an argument that in hybrid regimes, different levels of party competition incentivize incumbents to subvert the police in distinct ways, resulting in more corrupt or more repressive policing practices. In competing-pyramid hybrid regimes, such as Ukraine (2013–2019), elites have stronger incentives to preserve police corruption as a tool for immediate resource extraction amid

Longitudinal and lateral control of vehicle platoons : A unifying framework to prevent corner cutting

The formation of platoons, where groups of vehicles follow each other at close distances, has the potential to increase road capacity. In this paper, a decentralized control approach is presented that extends the well-known constant headway vehicle following approach to the two-dimensional case, i.e., lateral control is included in addition to the longitudinal control. The presented control scheme

Gain of chromosome 17 is an early genetic abnormality in neuroblastoma with PPM1D emerging as a strong candidate oncogene driving tumor progression

Segmental gain of chromosome 17q is the most common genetic aberration in high-risk neuroblastoma, but its role in disease progression is poorly understood. This study aims to address the contribution of 17q gain to neuroblastoma malignancy. We analyzed the genetic and transcriptional landscape of 417 neuroblastoma patients across various risk groups and clinical stages using multi-omic approaches

Invasive Coronary Angiography has Limited Diagnostic Accuracy for Detecting Reduction of Myocardial Perfusion Assessed by Cardiac Magnetic Resonance

The relationship between degree of coronary artery stenosis and its effect on myocardial perfusion is complex and constitutes a clinical challenge. The aim of this study was to assess diagnostic accuracy of visual assessment of invasive coronary angiography (ICA) for detecting reduced myocardial perfusion determined by quantitative first-pass perfusion (qFPP) cardiac magnetic resonance (CMR) in pa

Functional-gradient WC-TiC cemented carbides with alternative binders (Ni and Fe)

In this work we investigate the development of functionally graded cemented carbides, featuring macro gradients on the millimeter scale, where Fe, or Ni is the binder phase. Two composites, WC-Ni and WC-Fe with 20 % binder by volume were produced by addition of TiC on the surface of the samples before sintering at 1475 °C for 1 h. The sintered samples were analyzed using electron microscopy and mi

Risk of preeclampsia and gestational diabetes after occupational exposure to chemicals during pregnancy–A cohort study of births in Sweden 1994–2014

Many women are occupationally active during pregnancy. The aim of this study was to investigate associations between exposure to chemicals during pregnancy and the risk of gestational diabetes or preeclampsia. The cohort included singleton births in Sweden between 1994 and 2014. The cohort was limited to low-educated mothers to reduce potential confounding from unidentified life-style associated f

Minerals, microbes and melanin drive differential incorporation of fungal necromass carbon and nitrogen into mineral-associated organic matter

Despite the importance of mineral-associated organic matter (MAOM) in long-term soil carbon (C) and nitrogen (N) persistence, and the significant contribution of fungal necromass to this pool, the factors controlling the formation of fungal-derived MAOM remain unclear. This study investigated how fungal necromass chemistry, specifically melanin, interacts with soil mineral properties and microbial

Diagnostic pathways for earlier diagnosis and treatment towards better outcomes for adults living with chronic breathlessness

Chronic breathlessness is a common and distressing symptom, negatively impacting physical function and quality of life. Many individuals presenting with chronic breathlessness wait years for an explanatory diagnosis, leading to delays in accessing effective treatments and worse individual outcomes including premature mortality. In addition, delays to diagnosis are associated with increased healthc

Dexamethasone disrupts skull bone marrow-dura mater border, prolonging parameningeal infection in mice intranasally inoculated with E. coli

The incidence of parameningeal infection (PI) is increasing in the context of therapy-induced immunosuppression. PI often presents with atypical symptoms, leading to delayed diagnosis and intervention, and can result in severe neurological sequelae. However, current understanding of PI remains limited due to a lack of basic research on host-pathogen interactions. Here, we first established a trans

Smallholder Hibernation : Moonlight farming in the age of large scale agriculture

In this snapshot of moonlight farming in Scania, the southernmost province of Sweden, we reflect on moonlighting as a preservation strategy – a particular form of rural life different from the processes of agricultural upscaling and the rhythms and values of large-scale farming. Our immersion in the lives of three moonlight farmers tells a story of resistance, preservation and sense-scapes – a sta

Produktutveckling av en storformatskamera

Detta examensarbete har som mål att ta fram en modern tolkning av det gamla konceptet storformatskamera genom moderna designprocesser och tillverkningsmetoder. För att genomföra projektet har designramverket Double Diamond använts, en divergerande och konvergerande designprocess. En kundundersökning genomfördes genom intervjuer av användare. Informationen från intervjuerna, samt från en konkurrenThis thesis has the goal of developing a modern interpretation of the old concept of large format cameras, through modern design and manufacturing processes. The overarching design framework for this thesis has been the Double Diamond method, a diverging and converging design process. A customer survey through interviews of users has led to a list of requirements, from which concepts were generat

How to build (in) the future? Legitimacy of socio-technical visions in a bio-based construction sector

The use of bio-based materials offers opportunities to mitigate the climate impacts of construction, with buildings potentially acting as carbon sinks. However, it remains unclear what a future bio-based construction sector will look like. One reason for this are diverse socio-technical visions for the use of bio-based construction materials. In this paper, we use discourse analysis across a compr

When ammonia addition increases the burning velocity of a fuel blend with nitromethane

Combustion properties and combustion chemistry of ammonia (NH₃) are significantly different from those of hydrocarbons and thus require further investigation. NH₃ combustion with oxidizers different from the ambient air can reveal distinct chemistry of NOx formation, which, together with low reactivity, is one of the major obstacles in the direct deployment of ammonia as a practical fuel. In the p

Midwives’ experiences of working with menopause counselling : a qualitative study

Background: Studies have shown that women are asking for more knowledge and guidance about menopause. The professional competence of midwives encompasses menopause as a potential area of expertise. Midwives have good knowledge of women's health and are used to providing health advice. Aim: The aim was to examine midwives’ experiences of working with menopause counselling. Methods: Data were collec

Acritarch distribution in the Middle Ordovician of Öland, Sweden : Ecostratigraphical or biostratigraphical signal?

The Middle Ordovician of the palaeocontinent Baltica provides some of the best preserved and most diverse acritarch assemblages of the lower Palaeozoic. A great number of widely used acritarch genera and species have been described from this area since the 1960s and many of these taxa are considered as biostratigraphically useful for both regional and international correlation. Here, we document t

Investigating the therapeutic potential of FLASH radiotherapy – a treatment planning study

Purpose/Background: Ultra-high dose rate radiotherapy (RT) has shown potential for differential normal tissue (NT) sparing (a phenomenon termed the “FLASH effect”), particularly for larger fraction doses (>5 Gy). However, transitioning to hypofractionation may increase late-reacting NT toxicity, counteracting the FLASH effect. This study evaluates whether FLASH-RT can provide netsparing for organs

Compulsions in trauma-exposed patients with obsessive-compulsive disorder : Differences in prevalence and impact on treatment response

The effectiveness of exposure and response prevention (ERP), a front-line treatment for obsessive-compulsive disorder (OCD), is contingent on reducing engagement in compulsions, though recent research has found that certain compulsions may be less amenable to ERP. Given the impact of trauma exposure on OCD compulsions, the present study sought to examine whether compulsion-specific differences in

Molecular treatments to reduce catabolic effects in human meniscus explant models

Objectives: 1. To validate catabolic meniscus explant models induced by cytokines: interleukin-6 ​+ ​interleukin-6 receptor ​+ ​tumor necrosis factor alpha (IL6/TNF) and oncostatin M ​+ ​tumor necrosis factor alpha (OSM/TNF). 2. To evaluate three potential anti-catabolic treatments: i) dexamethasone (DEX), ii) a Link-N peptide (Link-N) and iii) a peptide from chondroadherin (CKF). Design: Healthy

A lumped parameter model of the coronary circulation incorporating time-varying resistance, intramyocardial pressure and vascular compliance

Conventional lumped parameter models (LPMs) simulate coronary flow incorporating intramyocardial pressure and vascular compliance, but assuming constant resistance despite its dynamic changes during myocardial contraction. We developed a coronary LPM incorporating time-varying resistance, intramyocardial pressure and vascular compliance to simulate phasic flow, critically evaluating key contributi