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Visible-light-driven hydrogen evolution using nitrogen-doped carbon quantum dot-implanted polymer dots as metal-free photocatalysts

Given the photocatalytic properties of semiconducting polymers and carbon quantum dots (CQDs), we report a new structure for a metal-free photocatalytic system with a promising efficiency for hydrogen production through the combination of an organic semiconducting polymer (PFTBTA) and N-doped carbon quantum dots (NCQDs) covered by PS-PEGCOOH to produce heterostructured photocatalysts in the form o

Towards homogenization of total body irradiation practices in pediatric patients across SIOPE affiliated centers. A survey by the SIOPE radiation oncology working group

Background and purpose: To reduce relapse risk, Total Body Irradiation (TBI) is part of conditioning regimens for hematopoietic stem cell transplantation (HSCT) in pediatric acute leukemia. The study purpose was to evaluate clinical practices regarding TBI, such as fractionation, organ shielding and delivery techniques, among SIOPE affiliated radiotherapy centers. Methods: An electronic survey was

Land-för-land­rapportering av skatter – en ur hållbarhets­vinkel missad möjlighet

I den här artikeln redogör Axel Hilling, Niklas Sandell, Amanda Sonnerfeldt och Anders Vilhelmsson för utvecklingen av offentlig land-förlandrapportering av skatter inom EU. Författarna analyserar hur den aktuella regleringen förhåller sig till EU:s nya direktiv för hållbarhetsrapportering, Corporate Sustainability Reporting Directive, CSRD.

Volcanic temperature changes modulated volatile release and climate fluctuations at the end-Triassic mass extinction

Emplacement of the Central Atlantic Magmatic Province (CAMP) is thought to have triggered global environmental changes and the end-Triassic mass extinction (ETE). However, the mechanisms linking volcanism and environmental change are unclear. Here we provide new insight into these linkages by measuring the abundance of both sedimentary five- to six-ring polycyclic aromatic hydrocarbons (PAHs) and

Cold-induced anesthesia impairs path integration memory in dung beetles

Path integration is a general mechanism used by many animals to maintain an updated record of their position in relation to a set reference point.1–11 To do this, they continually integrate direction and distance information into a memorized home vector. What remains unclear is how this vector is stored, maintained, and utilized for successful navigation. A recent computational model based on the

Stability and phase transitions of dynamical flow networks with finite capacities

We study deterministic continuous-time lossy dynamical flow networks with constant exogenous demands, fixed routing, and finite flow and buffer capacities. In the considered model, when the total net flow in a cell —consisting of the difference between the total flow directed towards it minus the outflow from it— exceeds a certain capacity constraint, then the exceeding part of it leaks out of the

Marketization in Crisis : The Political Economy of COVID-19 and the Unmaking of Public Transport in Stockholm

While measures to prevent the spread of COVID-19 disturbed both global and local markets, some commentators also argued that the pandemic could be seen as the beginning of the end of neoliberalism. Although neoliberal reforms have come under pressure, little is known about the implications of COVID-19 in or across specific sectors. Scaling down the rich theoretical–historical debates about neolibe

Cystatin C Plays a Sex-Dependent Detrimental Role in Experimental Autoimmune Encephalomyelitis

The cysteine protease inhibitor Cystatin C (CST3) is highly expressed in the brains of multiple sclerosis (MS) patients and C57BL/6J mice with experimental autoimmune encephalomyelitis (EAE; a model of MS), but its roles in the diseases are unknown. Here, we show that CST3 plays a detrimental function in myelin oligodendrocyte glycoprotein 35-55 (MOG35-55)-induced EAE but only in female animals. F

Optical Characterization of Methanol Sprays and Mixture Formation in a Compression-Ignition Heavy-Duty Engine

Methanol is not a fuel typically used in compression ignition engines due to the high resistance to auto-ignition. However, conventional diesel combustion and PPC offer high engine efficiency along with low HC and CO emissions, albeit with the trade-off of increased NOx and PM emissions. This trade-off balance is mitigated in the case of methanol and other alcohol fuels, as they bring oxygen in th

Association of post-diagnostic use of cholera vaccine with survival outcome in breast cancer patients

BACKGROUND: Expensive cancer treatment calls for alternative ways such as drug repurposing to develop effective drugs. The aim of this study was to analyse the effect of post-diagnostic use of cholera vaccine on survival outcome in breast cancer patients.METHODS: Cancer diagnosis and cholera vaccination were obtained by linkage of several Swedish national registries. One vaccinated patient was mat

Using collective intelligence to enhance demand flexibility and climate resilience in urban areas

Collective intelligence (CI) is a form of distributed intelligence that emerges in collaborative problem solving and decision making. This work investigates the potentials of CI in demand side management (DSM) in urban areas. CI is used to control the energy performance of representative groups of buildings in Stockholm, aiming to increase the demand flexibility and climate resilience in the urban

A circular RNA generated from an intron of the insulin gene controls insulin secretion

Fine-tuning of insulin release from pancreatic β-cells is essential to maintain blood glucose homeostasis. Here, we report that insulin secretion is regulated by a circular RNA containing the lariat sequence of the second intron of the insulin gene. Silencing of this intronic circular RNA in pancreatic islets leads to a decrease in the expression of key components of the secretory machinery of β-c

Type 2 diabetes risk gene Dusp8 regulates hypothalamic Jnk signaling and insulin sensitivity

Recent genome-wide association studies (GWAS) identified DUSP8, encoding a dual-specificity phosphatase targeting mitogen-activated protein kinases, as a type 2 diabetes (T2D) risk gene. Here, we reveal that Dusp8 is a gatekeeper in the hypothalamic control of glucose homeostasis in mice and humans. Male, but not female, Dusp8 loss-of-function mice, either with global or corticotropin-releasing ho

COVID-19 during Pregnancy and Postpartum : Antiviral Spectrum of Maternal Lactoferrin in Fetal and Neonatal Defense

As the COVID-19 pandemic intensified the global health crisis, the containment of SARS-CoV-2 infection in pregnancies, and the inherent risk of vertical transmission of virus from mother-to-fetus (or neonate) poses a major concern. Most COVID-19-Pregnancy patients showed mild to moderate COVID-19 pneumonia with no pregnancy loss and no congenital transmission of the virus; however, an increase in

Interdependence of photon upconversion performance and antisolvent processing in thin-film halide perovskite-sensitized triplet-triplet annihilators

We prepared triplet-triplet annihilation photon upconverters combining thin-film methylammonium lead iodide (MAPI) perovskite with a rubrene annihilator in a bilayer structure. Excitation of the perovskite film leads to delayed, upconverted photoluminescence emitted from the annihilator layer, with triplet excitation of the rubrene being driven by carriers excited in the perovskite layer. To bette

MSLibrarian: Optimized Predicted Spectral Libraries for Data-Independent Acquisition Proteomics

Data-independent acquisition-mass spectrometry (DIA-MS) is the method of choice for deep, consistent, and accurate single-shot profiling in bottom-up proteomics. While classic workflows for targeted quantification from DIA-MS data require auxiliary data-dependent acquisition (DDA) MS analysis of subject samples to derive prior-knowledge spectral libraries, library-free approaches based on in silic