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On the discovery of new elements (IUPAC/IUPAP Provisional Report) : Provisional Report of the 2017 Joint Working Group of IUPAC and IUPAP

Almost thirty years ago the criteria that are currently used to verify claims for the discovery of a new element were set down by the comprehensive work of a Transfermium Working Group, TWG, jointly established by IUPAC and IUPAP. The recent completion of the naming of the 118 elements in the first seven periods of the Periodic Table of the Elements was considered as an opportunity for a review of

IL-33 drives influenza-induced asthma exacerbations by halting innate and adaptive antiviral immunity

Background: Influenza virus triggers severe asthma exacerbations for which no adequate treatment is available. It is known that IL-33 levels correlate with exacerbation severity, but its role in the immunopathogenesis of exacerbations has remained elusive. Objective: We hypothesized that IL-33 is necessary to drive asthma exacerbations. We intervened with the IL-33 cascade and sought to dissect it

The Diabetic Foot Syndrome Today : A Pandemic Uprise

Diabetes mellitus is growing at epidemic proportions worldwide; currently 415 million adults are estimated to have diabetes and by 2040, this number is estimated to increase to 642 million. As a consequence, the prevalence of diabetes-related complications is bound to increase. Diabetic foot disorders are common throughout the world, resulting in major medical, social and economic consequences for

Intralymphatic Immunotherapy : Update and Unmet Needs

Allergen-specific immunotherapy (AIT) is the only allergy treatment that confers long-term symptom amelioration for patients suffering from allergy. The most frequently used allergen application route is subcutaneous injection (SCIT), commonly taken as the gold standard, followed by sublingual (SLIT) or oral (OIT) application of allergen preparations. This is an up-to-date review of the clinical e

Stroke as a cause of death in death certificates of patients with dementia : A cohort study from the Swedish dementia registry

Introduction: Patients with dementia may be at a higher risk for death from stroke. We aimed to describe characteristics of dementia patients that died from ischemic stroke (IS) in Sweden. Methods: A retrospective longitudinal analysis of prospectively collected data of patients registered into the Swedish Dementia Registry was conducted. Data on causes of death, drugs and comorbidities were acqui

Societal causes of, and responses to, ocean acidification

Major climate and ecological changes affect the world’s oceans leading to a number of responses including increasing water temperatures, changing weather patterns, shrinking ice-sheets, temperature-driven shifts in marine species ranges, biodiversity loss and bleaching of coral reefs. In addition, ocean pH is falling, a process known as ocean acidification (OA). The root cause of OA lies in human

Migratory birds as vehicles for parasite dispersal? Infection by avian haemosporidians over the year and throughout the range of a long-distance migrant

Aim: The role of migratory birds in the spread of parasites is poorly known, in part because migratory strategies and behaviours potentially affecting transmission are not easy to study. We investigated the dynamics of infection by blood parasites through the annual cycle of a long-distance Nearctic–Neotropical migratory songbird to examine the role of this species in dispersing parasites between

Master student's application of evidence-based knowledge and skills in Swedish healthcare practice

Aim: To investigate the application of evidence-based knowledge and skills in everyday healthcare practice among healthcare personnel attending a course in evidence-based practice (EBP) at the master's level.Methods: In this cross-sectional study, an evaluation of the use of instrumental, conceptual and persuasive research was performed among students attending a master's course in EBP at Lund Uni

Nanosecond Tracer Diffusion as a Probe of the Solution Structure and Molecular Mobility of Protein Assemblies: The Case of Ovalbumin

Protein diffusion is not only an important process ensuring biological function but can also be used as a probe to obtain information on structural properties of protein assemblies in liquid solutions. Here, we explore the oligomerization state of ovalbumin at high protein concentrations by means of its short-time self-diffusion. We employ high-resolution incoherent quasielastic neutron scattering

Tuning phase transitions of aqueous protein solutions by multivalent cations

In the presence of trivalent cations, negatively charged globular proteins show a rich phase behaviour including reentrant condensation, crystallisation, clustering and lower critical solution temperature metastable liquid–liquid phase separation (LCST–LLPS). Here, we present a systematic study on how different multivalent cations can be employed to tune the interactions and the associated phase b

Nationalmuseum undergoing change

Behandlar premisserna för Nationalmuseums framtida verksamhet när det gäller renovering och nybyggnation på Blasieholmen.

Program for studying intergenerational transmissions in infant mortality using the intermediate data structure (IDS)

Studies conducted in historical populations and developing countries have evidenced the existence of clustering in infant deaths, which could be related to genetic inheritance and/or to social and cultural factors such as education, socioeconomic status or parental care. A transmission of death clustering has also been found across generations. One way of expanding the knowledge on intergeneration

Editorial

Historical Life Course Studies, a journal in population studies, aims to stimulate and facilitate the implementation of IDS (Intermediate Data Structure, a standard data format for large historical databases), and to publish the results from (comparative) research with the help of large historical databases. The journal publishes not only empirical articles, but also descriptions (of the construct

A comprehensive screening of copy number variability in dementia with Lewy bodies

The role of genetic variability in dementia with Lewy bodies (DLB) is now indisputable; however, data regarding copy number variation (CNV) in this disease has been lacking. Here, we used whole-genome genotyping of 1454 DLB cases and 1525 controls to assess copy number variability. We used 2 algorithms to confidently detect CNVs, performed a case-control association analysis, screened for candidat