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By definition, radiofrequency (RF) pulses are the pivotal elements of NMR pulse sequences. Vice versa, the effect of a particular pulse on the evolution of magnetization will depend on the context of the sequence. While the product operator formalism provides a general framework to describe the effect of hard pulses on weakly coupled spin systems, there is no consistent framework describing the ef

Prostate cancer risk SNP rs10993994 is a trans-eQTL for SNHG11 mediated through MSMB

How genome-wide association studies-identified single-nucleotide polymorphisms (SNPs) affect remote genes remains unknown. Expression quantitative trait locus (eQTL) association meta-analysis on 496 prostate tumor and 602 normal prostate samples with 117 SNPs revealed novel cis-eQTLs and trans-eQTLs. Mediation testing and colocalization analysis demonstrate that MSMB is a cis-acting mediator for S

What do patients prefer? A multinational, longitudinal, qualitative study on patient-preferred treatment outcomes in early rheumatoid arthritis

OBJECTIVES: To explore treatment outcomes preferred by patients with early rheumatoid arthritis (RA) and how these change throughout the early disease stage across three European countries. METHODS: A longitudinal, qualitative, multicentre study was conducted in Belgium, the Netherlands and Sweden. 80 patients with early RA were individually interviewed 3-9 months after treatment initiation and 51

Globalization, Recruitments and Job Mobility

Previous research indicates that exporting firms are willing to pay a premium to poach workers from other exporting firms if experience working for an internationally engaged firm reduces trade costs. Since international experience is less valuable to non-exporters, we would expect to see differences in recruitments between firms that are internationally engaged and those that serve only their dom

Ideella organisationers medverkan i tvister på dataskyddsrättens område

EU:s dataskyddsförordning innehåller bestämmelser om vissa ideella organisationers behörighet att uppträda som ombud för registrerade samt om sådan organisationers talerätt. Syftet med denna artikel är att undersöka vilka möjligheter sådana organisationer enligt gällande svensk rätt har att delta i övervakningen av dataskyddsreglernas efterlevnad.

Putative reaction mechanism of nitrogenase after dissociation of a sulfide ligand

We have investigated the implications of the recent crystallographic findings that the m2-bridging S2B sulfide ligand may reversibly dissociate from the active-site FeMo cluster of nitrogenase. We show with combined quantum mechanical and molecular mechanical (QM/MM) calculations that once S2B has dis- sociated, N2 may bind in that position and can be protonated to two NH3 groups by thermodynamica

Risk of invasive prostate cancer and prostate cancer death in relatives of patients with prostatic borderline or in situ neoplasia : A nationwide cohort study

BACKGROUND: The question of whether having a family history of prostatic borderline or in situ neoplasia (PBISN) is associated with an increased risk of invasive prostate cancer (PCa) or death from PCa remains unanswered. The objective of the current study was to provide an evidence-based risk estimation for the relatives of patients with PBISN.METHODS: Nationwide Swedish family cancer data sets w

Perioperative management in order to minimise postoperative delirium and postoperative cognitive dysfunction : Results from a Swedish web-based survey

Cognitive side-effects such as emergence agitation (EA), postoperative delirium (POD) and postoperative cognitive dysfunction (POCD) are not infrequently complicating the postoperative care especially in elderly and fragile patients.The aim of the present survey was to gain insight regarding concern and interest in prevention and treatment strategies for postoperative delirium and dysfunction, and

Evaluation of the Postoperative Quality of Recovery Scale test and re-test in Swedish among healthy volunteers

Introduction Patient outcome measures are required to assess the quality of healthcare. Tools for a patients' self-assessment of quality of recovery, during perioperative care, have been developed during the last decade. The Postoperative Quality of Recovery Scale (PostopQRS) questionnaire is one of the most well-accepted and validated tools available. Here we assess the PostopORS questionnaire in

Mal de débarquement syndrome : Diagnostic criteria consensus document of the classification committee of the bárány society

We present diagnostic criteria for mal de débarquement syndrome (MdDS) for inclusion into the International Classification of Vestibular Disorders. The criteria include the following: 1] Non-spinning vertigo characterized by an oscillatory sensation ('rocking,' 'bobbing,' or 'swaying,') present continuously or for most of the day; 2] Onset occurs within 48 hours after the end of exposure to passiv

En farlig tid för män?

Gabriella Nilsson är docent och lektor vid institutionen för kulturvetenskaper på Lunds universitet. Här berättar hon om varför vi, till skillnad från vad bland annat personer som president Donald Trump och författaren Horace Engdahl sagt, inte lever i "en farlig tid för män". Inspelat den 8 mars 2019 på Lunds universitet.

Överlappningen mellan dataskydd och marknadsrätt : Dataskyddsförordningens tillämpning på marknadsföring och marknadsrättens tillämpning på kommersiell personuppgiftsbehandling

Digitaliseringen gör det möjligt för näringsidkare att utveckla nya affärsmodeller, upptäcka nya marknader och att rationalisera sina verksamheter.En viktig aspekt i denna utveckling utgör att samla in, behandla och på olika sätt utnyttja personuppgifter av såväl befintliga som presumtiva kunder. Av den anledningen existerar ett naturligt samband mellan personuppgifter och näringsverksamhet och fr