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Advanced clinical MRI for better outcome in epilepsy surgery. Focusing on fMRI and prediction of verbal memory decline.

Abstract Aim: The aim of the thesis was to evaluate the use of advanced MRI technology to improve results of epilepsy surgery, with focus on language and memory functions. Methods: In paper I, 25 patients with drug-resistant epilepsy were retrospectively included in the study for having been referred to high resolution 3T MRI with and without surface coils. The surface coils were placed over the s

Genetic algorithm approach for QoS-based tree topology construction in IEEE 802.16 mesh networks

The topological characteristics of an IEEE 802.16 mesh network including the tree’s depth and degree of its nodes affect the delay and throughput of the network. To reach the desired trade-off between delay and throughput, all potential trees should be explored to obtain a tree with the proper topology. Since the number of extractable tree topologies from a given network graph is enormous, we use

Search for pair production of heavy top-like quarks decaying to a high-p(T) W boson and a b quark in the lepton plus jets final state at root s=7 TeV with the ATLAS detector

A search is presented for production of a heavy up-type quark (t') together with its antiparticle, assuming a significant branching ratio for subsequent decay into a W boson and a b quark. The search is based on 4.7 fb(-1) of pp collisions root s = 7 TeV recorded in 2011 with the ATLAS detector at the CERN Large Hadron Collider. Data are analyzed in the lepton + jets final state, characterized by

Molecular and microscopical analysis of pathogenic streptococci - studies on surface proteins interacting with human cells and extracellular matrix

Popular Abstract in Swedish Vi är omringade av olika mikrorganismer såsom bakterier och svampar. Bakterier kan leva från de mest ogästvänliga miljöer som arktisk is och varma källor på havsbotten till varje människas hud och mag- tarmkanal. Bakterier som bor på och inuti oss spelar en stor roll i vårt välbefinnande. De hjälper oss att smälta maten och hindrar andra mer farliga bakterier från att bAssociation to specific host tissue structures allows pathogenic bacteria to establish an infection and facilitates the spread within its host. Interactions between bacterial surface structures and human proteins might determine the outcome of the infection. Streptococcus pyogenes (S. pyogenes), is a human pathogen mostly causing localized infections of the skin and respiratory tract, but it is al

Tolerability and efficacy of inhaled AZD4818, a CCR1 antagonist, in moderate to severe COPD patients

Objective: This study evaluated the tolerability and efficacy of inhaled AZD4818, a CCR1 antagonist, in patients with COPD. Methods: This double-blind, placebo-controlled study (NCT00629239) randomised patients with moderate to severe COPD to AZD4818 300 mu g or placebo twice daily via Turbuhaler (R) for 4 weeks. Safety, lung function, functional capacity and health status measures were measured.

The Healthcare Voucher: Emergence, Formation and Dissemination

Market-inspired healthcare reforms have been introduced in Sweden: Freedom of Choice in Healthcare in 1989 and the National Healthcare Guarantee in 2005. After the general election 2006 the idea of the Healthcare Voucher has followed. Built on a theoretical framework composed of Foucault's concept of 'discursive formation' supported by Butler's concept of the ‘performativity of discourse’ the purp

Influence of bark on fuel ethanol production from steam-pretreated spruce.

Bark and bark-containing forest residues have the potential for utilization as raw material for lignocellulosic ethanol production due to their abundance and low cost. However, the different physical properties and chemical composition of bark compared to the conventionally used wood chips may influence the spruce-to-ethanol bioconversion process. This study assesses the impact of bark on the over

Adaptive impedance matching performance of MIMO terminals with different bandwidth and isolation properties in realistic user scenarios

Using the metric of channel capacity, three dual-antenna multiple-input multiple-output (MIMO) terminals with adaptive impedance matching were evaluated at LTE Band 13 in four different user scenarios using simulation. Each of the three terminals is equipped with a slot-monopole antenna and a planar inverted-F antenna (PIFA). The slot monopole is fixed at one edge of the chassis, whereas the locat

pH-responsive liposome-templated polyelectrolyte nanocapsules

Hollow nanocapsules made of polyelectrolytes, extensively useful for biomedical and biotechnological applications, are produced with a simple Layer-by-Layer approach using liposomes as template. The biocompatible polymers, alginate and chitosan, are alternatively adsorbed onto liposomes allowing the achievement of small size hollow nanocapsules with an average diameter of similar to 280 nm. Hollow

Diabetes Mellitus Glucose Prediction by Linear and Bayesian Ensemble Modeling

Diabetes Mellitus is a chronic disease of impaired blood glucose control due to degraded or absent bodily-specific insulin production, or utilization. To the affected, this in many cases implies relying on insulin injections and blood glucose measurements, in order to keep the blood glucose level within acceptable limits. Risks of developing short- and long-term complications, due to both too high

Predicting long-term carbon sequestration in response to CO2 enrichment: How and why do current ecosystem models differ?

Large uncertainty exists in model projections of the land carbon (C) sink response to increasing atmospheric CO2. Free-Air CO2 Enrichment (FACE) experiments lasting a decade or more have investigated ecosystem responses to a step change in atmospheric CO2 concentration. To interpret FACE results in the context of gradual increases in atmospheric CO2 over decades to centuries, we used a suite of se

Inductive tongue control of powered wheelchairs

Alternative and effective methods for controlling powered wheelchairs are important to individuals with tetraplegia and similar impairments whom are unable to use the standard joystick. This paper describes a system where tongue movements are used to control a powered wheelchair thus providing users, with high level spinal cord injuries, full control of their wheelchair. The system is based on an

G protein-coupled estrogen receptor 1 (GPER) in the female reproductive tract: from physiology to cancer

Popular Abstract in Swedish Östrogen är ett av de viktigaste/ mest studerade kvinnliga könshormonerna som styr utvecklingen av våra fortplantningsorgan och deras reproduktionsförmåga. Östrogen påverkar dessutom många av kroppens andra organ, bland annat hjärnan, skelettet, och hjärt-kärlsystemet. Mängden östrogen som finns i kroppen varierar vanligtvis under menstruationscykeln och med kvinnans ålEstrogen effects are mediated either through genomic action involving the classical estrogen receptors, estrogen receptor alpha (ERα) and beta (ERß), which function as transcription factors in the nucleus, or through rapid non-genomic action via receptors associated with plasma membrane. Recently, a member of the G protein-coupled receptor family was ascribed estrogen receptor properties and propo

Cell-line-specific stimulation of tumor cell aggressiveness by wound healing factors - a central role for STAT3

Background: Local recurrence is a major factor affecting survival after treatment for head and neck squamous cell carcinoma (HNSCC). It is possible that the normal processes involved in wound healing after surgical removal of a primary tumor can boost the regrowth of residual cancer cells, thereby contributing to the recurrent growth. In this work, we collected human wound fluids and used them to

Testing the quality of carriers: a field experiment on lizard signallers

In the Australian painted dragon lizard (Ctenophorus pictus), males occur in two different morphs with respect to gular color, with or without a yellow bib. Males without a bib lost within-clutch paternity significantly more often to rivals than bibbed males. Thus, it appears that bibs identify some phenotypic advantage linked to competitive ability. To test whether this could be related to whole-

Hypotermi efter perinatal asfyxi minskar risken för hjärnskada. Men för tidigt att rekommendera rutinmässig behandling

Måttlig hypotermi efter perinatal asfyxi reducerar mortaliteten och risken för överlevnad med svårt handikapp, visar två randomiserade, kontrollerade studier. Fler studier pågår och förväntas bli publicerade inom de närmaste åren. Den publicerade studien visar dock att det endast är barn med måttlig hjärnskada som har effekt av hypotermi. Hypotermi efter perinatal asfyxi kan ännu inte rekommenderaTwo randomised controlled trials evaluating intervention with moderate hypothermia after perinatal asphyxia will probably be published this year. The first study, evaluating head cooling with a "cool cap" is already published, and preliminary data from the other study evaluating body cooling earlier have been presented. Both studies indicate that moderate hypothermia, initiated within 6 h after bi

Skräddaren, sömmerskan och modet : arbetsmetoder och arbetsdelning i tillverkningen av kvinnlig dräkt 1770-1830

The aim of this study in textile studies and cultural history is to gain a greater understanding of what happened to the division of labour and manufacturing techniques when female fashions changed in the period 1770-1830. This was a time of upheaval as regards fashions, and a change in dress practice. The decades around 1800 were a period of major societal and cultural transformation. Female fash

Lavar på Jordö

Denna rapport baseras på två inventeringar. Dels en inventering av sten- och jordlavar som genomfördes den 25 juli 2009 av Lars Fröberg, dels en inventeringen av skyddsvärda träd som genomfördes mellan 21 oktober och 12 november 2008 av Mattias Lif och Sofie Willman. Jordö är en halvö vid västra delen av Almö som ligger i norra delen av Listerby skärgård. Området är troligtvis ett av de artrikaste