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NMR studies of molecular mobility in a DNA-amphiphile complex

The molecular mobility in a hexagonal DNA-cationic surfactant complex is studied using H-1 and C-13 nuclear magnetic resonance spectroscopy. The charge-compensated complex can swell in water up to a content of approximately seven water molecules per charge. The NMR measurements show that in the dry state the alkyl chains of the surfactant have the properties of a disordered solid with internal mot

Electrical wiring of pyranose oxidase with osmium redox polymers

Two different flexible osmium functionalised polymers were investigated for their ability to efficiently "wire" pyranose oxidase when immobilised on graphite electrodes. The two Os-polymers differ in redox potential and the length of the side chains, where the Os2+/3+-functionalities are located. The performance of the redox polymers as mediators for the enzyme was tested with glucose. As well as

2.5D resistivity modeling of embankment dams to assess influence from geometry and material properties

Repeated resistivity measurement is a potentially powerful method for monitoring development of internal erosion and anomalous seepage in earth embankment dams. This study is part of a project to improve current longterm monitoring routines and data interpretation and increasing the understanding when interpreting existing data. This is accomplished by modeling various occurrences typical of emban

Spectroscopic data for Hg I and Hg II from beam-foil spectroscopy

The spectroscopic data mercury (Hg) I and Hg II was analyzed from beam-foil spectroscopy. The wavelength was found to be of course fixed and independent of the light source and recording conditions. It was found that if the calculated branching ratio was correct, then the Hg II was an important constituent of fluorescent light tube plasmas. The wavelength region from 40 to 600 nm in overlapping wa

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The effect and possible mechanisms of action of aminoguanidine (a preferential iNOS inhibitor) has been studied on cardiovascular damages and overproduction of reactive nitrogen species in streptozotocin-induced diabetic rats. MATERIALS AND METHODS: 40 rats were divided into five groups (control and diabetic, with or without aminoguanidine treatment, diabetic with insulin treatment) and oxidative

A mechanical stretch induces contractile activation in unstimulated developing rat skeletal muscle in vitro

The effects of a stretch-release cycle (25 of the resting muscle fibre length, Lo) on both tension and [Ca2+i in small, unstimulated, intact muscle fibre bundles isolated from adult and neonatal rats were investigated at 20 C. The results show that the effects of the length change depended on the age of the rats. Thus, the length change produced three effects in the neonatal rat muscle fibre bundl

Simulation of chromatographic processes using MATLAB

This paper deals with the dynamic simulation of chromatographic processes using MATLAB. Three different simulation tools are presented,; BIOPRO2, CPS toolbox and an application using of FEMLAB. Our main application is separation of biomolecules, like proteins, using different kinds of stationary phases. BIOPRO2 has a user-friendly graphical interface and is mainly based on simplified models for fa

Magnetic resonance imaging and MR angiography of endoluminally treated abdominal aortic aneurysms

OBJECTIVES: To evaluate magnetic resonance imaging (MRI) with gadolinium-based contrast medium-enhanced MR angiography (MRA) for the follow-up of endoluminally treated abdominal aortic aneurysms. DESIGN: MRI/MRA, angiography and computed tomography (CT) were performed 1 month after endoluminal stent-graft placement. MRI/MRA was repeated at 6 and 12 months and angiography and CT were added to confi

The Lund Nuclear Microprobe sub-micron set-up. Part II: Beam line, focusing system and scanning

A new beam line for generating a sub-micron beam spot for high-resolution nuclear microprobe applications has been constructed at the Lund Nuclear Microprobe facility. The design and construction of the beam line, the quality test of the four high precision Oxford OM-52 Quadrupole magnets by the grid shadow method and the beam scanning system are presented in this paper. The beam line is designed

Correlated electron tunneling in the single-molecule nanosystems

The original approach to the creation of high-temperature single-electron tunneling systems has been developed based on the use of nanocluster molecules. The morphology and electron tunneling characteristics through single nanocluster molecules organized as highly-ordered monolayer Langmuir-Blodgett films on atomically-flat graphite substrate have been studied experimentally using scanning tunneli

Vertebral deformation in urban Swedish men and women: prevalence based on 797 subjects

Vertebral fracture-deformation, a common feature of osteoporosis, shows considerable age, sex and geographical variation. We present the prevalence in an urban population of south-west Sweden. Lateral spine radiographs of 797 men and women, age 50-86 years, were evaluated by morphomety. The age-standardized prevalence of subjects with vertebral deformation using the deformation criterion -3 SD was

Elevated glucose levels promote contractile and cytoskeletal gene expression in vascular smooth muscle via Rho/protein kinase C and actin polymerization.

Both type 1 and type 2 diabetes are associated with increased risk of cardiovascular disease. This is in part attributed to the effects of hyperglycemia on vascular endothelial and smooth muscle cells but the underlying mechanisms are not fully understood. In diabetic animal models, hyperglycemia results in hyper-contractility of vascular smooth muscle possibly due to increased activation of Rho-k

Consanguinity and genetic diseases in North Africa and immigrants to Europe.

Endemic diseases are caused by environmental and genetic factors. While in this special issue several chapters deal with environmental factors, including infections, the present focus is on genetic causes of disease clustering due to inbreeding and recessive disease mechanisms. Consanguinity is implying sharing of genetic heritage because of marriage between close relatives originating from a comm