Background: Having knowledge of which patients are more likely to experience fatigue during radiotherapy and the relationship between fatigue and health-related quality of life (HRQL) is important to improve identification and care of patients experiencing burdensome fatigue. Objective: To identify subgroups of patients, varying in situational, physiological, and psychological factors, who are mor

Objective: To estimate the risk of developing comorbidities in patients after physician-diagnosed knee or hip osteoarthritis (OA). Methods: This was a cohort study using Swedish longitudinal health care register data; we studied residents in the Skåne region age ≥35 years on January 1, 2010 who were free from diagnosed hip or knee OA (n = 548,681). We then identified subjects with at least 1 new d

Objective: The Systemic Lupus International Collaborating Clinics (SLICC) frailty index (FI) predicts mortality and damage accrual in systemic lupus erythematosus (SLE), but its association with hospitalizations has not been described. Our objective was to estimate the association of baseline SLICC-FI values with future hospitalizations in the SLICC inception cohort. Methods: Baseline SLICC-FI sco

The magnitude, direction and cause of precipitation changes across the Indo-Pacific Warm Pool (IPWP) during the Last Glacial Maximum (LGM) remain elusive. In particular, it is still inconclusive whether tropical or extra-tropical factors controlled such precipitation changes. Determining the spatio-temporal distribution of precipitation in the IPWP during the LGM is a valid strategy to address thi

The atomic arrangement of the terminating facets on spinel Co3O4 nanocrystals is strongly linked to their catalytic performance. However, the spinel crystal structure offers multiple possible surface terminations depending on the synthesis. Thus, understanding the terminating surface atomic structure is essential in developing high-performance Co3O4 nanocrystals. In this work, we present direct at

Objective: To estimate the cost-effectiveness of strategies to prevent spontaneous preterm delivery (PTD) in asymptomatic singleton pregnancies, using prevalence and healthcare cost data from the Swedish healthcare context. Methods: We designed a decision analytic model based on the Swedish CERVIX study to estimate the cost-effectiveness of strategies to prevent spontaneous PTD in asymptomatic wom

High-throughput sequencing of adaptive immune receptor repertoires (AIRR, i.e., IG and TR) has revolutionized the ability to carry out large-scale experiments to study the adaptive immune response. Since the method was first introduced in 2009, AIRR sequencing (AIRR-Seq) has been applied to survey the immune state of individuals, identify antigen-specific or immune-state-associated signatures of i

The negative impact of maritime traffic in terms of shore erosion in sheltered coastal fairways can be mitigated by sustainable fairway management. Mitigation measures include regulating the ship traffic in terms of speed, routes, or size of ships, but can also involve erosion protection along a fairway. For effective shoreline management of a fairway, it is essential to predict ship waves, to ide

The rhizosphere priming effect (RPE) is increasingly being considered to be an important regulator of soil organic matter (SOM) decomposition and nutrient turnover, with potential importance for the global CO2 budget. As a result, studies on the RPE have rapidly increased in number over the last few years. Most of these experiments have been performed using unplanted soil as the control, which cou

There is substantial evidence that women tend to support different policies and political candidates than men. Many studies also document gender differences in a variety of important preference dimensions, such as risk-taking, competition and pro-sociality. However, the degree to which differential voting by men and women is related to these gaps in more basic preferences requires an improved unde

Previous studies have shown that belief in the healthiness of organic food is a strong motive for buying organic. Typically, a positive relation between a nutritionally balanced diet (with respect to fruit, vegetables and meat) and organic consumption is also found. As market shares of organic food are much smaller than those of conventional food, consumers may face a trade-off between buying orga

Background: In adults and adolescents with asthma, use of ≥3 short-acting β2-agonist (SABA) canisters/year is associated with increased exacerbation risk. Whether this association is present in younger children remains unknown. In this SABA use IN Asthma (SABINA) Junior study, we assessed the association of SABA collection with exacerbation risk in the general Swedish pediatric asthma population.

The important electrochemical processes in a battery happen at the solid/liquid interfaces. Operando ambient pressure photoelectron spectroscopy (APPES) is one tool to study these processes with chemical specificity. However, accessing this crucial interface and identifying the interface signal are not trivial. Therefore, we present a measurement setup, together with a suggested model, exemplifyin

PACs (polycylic aromatic compounds) are air pollutants formed in incomplete combustion, e.g., in vehicle engines. Vegetation can potentially remove substantial amounts and act as bioindicators of these pollutants. Increased knowledge of the pollutant removal efficiencies of different tree species is essential for understanding the potential benefits trees can provide urban residents. We investigat

Context. After more than two decades of relevant radial velocity surveys, the current sample of known brown dwarfs (BDs) around FGK stars is only of the order of 100, limiting our understanding of their occurrence rate, properties, and formation. The ongoing ESA mission Gaia has already collected more than its nominal 5 years of mission data, and is expected to operate for up to 10 years in total.

Relative telomere length (RTL), an indicator of senescence, has been shown to be heritable but can also be affected by environmental factors, such as parental effects. Investigating heritability as well as parental effects and rearing environment can help us to understand the factors affecting offspring telomeres. Moreover, how phenotypic parental traits linked with fitness can impact offspring RT

Background We recently identified an outbreak of occupational allergic contact dermatitis (ACD) involving workers of a Spanish company selling smartphone protective cases from a glue product. A chemical analysis of one glue sample revealed the presence of 4-acryloylmorpholine among other allergens. The same glue is also used to attach tempered glass protective cases to Apple smartwatches. Objectiv

We introduce and apply a new approach to probe the response of galactic stellar haloes to the interplay between cosmological merger histories and galaxy formation physics. We perform dark matter-only, zoomed simulations of two Milky Way-mass hosts and make targeted, controlled changes to their cosmological histories using the genetic modification technique. Populating each history's stellar halo w