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Modeling Nanosized Single Molecule Objects: Dendronized Polymers Adsorbed onto Mica

We attempt to provide direct evidence for the suggested behavior of dendronized polymers as molecular objects (i.e., single shape persistent macromolecules). For this purpose, the microscopic structure of dendronized polymers adsorbed onto mica has been investigated using atomistic molecular dynamics simulations. We find that the shape of the second to fourth generation dendronized polymers is bas

Balls Enough: Manliness and Legitimated Violence in Hell's Kitchen

This article presents one example of how masculinity and hierarchy are exercised through violence in organizations. It draws on the empirical data of 15 episodes from the US reality television series Hell’s Kitchen, in which 15 cooks compete for the job of Chef in one of celebrity chef Gordon Ramsay’s restaurants. Ramsay’s task is to lead the cooks towards a hegemonic masculinity valid in the rest

Genetics of personalities: no simple answers for complex traits

Identifying the genes that underlie phenotypic variation in natural populations, and assessing the consequences of polymorphisms at these loci for individual fitness are major objectives in evolutionary biology. Yet, with the exception of a few success stories, little progress has been made, and our understanding of the link between genotype and phenotype is still in its infancy. For example, alth

The Inflammatory Marker suPAR After Cardiac Arrest.

Background: Soluble urokinase plasminogen activator receptor (suPAR) is released in response to inflammatory stimuli, and plasma levels are associated with long-term outcomes. The ischemia/reperfusion injury caused by cardiac arrest (CA) and resuscitation triggers an inflammatory response. This pilot study aimed at investigating suPAR levels in relation to outcome after CA and mild induced hypothe

Environmental mercury exposure, semen quality and reproductive hormones in Greenlandic Inuit and European men: a cross-sectional study

Several animal studies indicate that mercury is a male reproductive toxicant, but human studies are few and contradictory. We examined semen characteristics and serum levels of reproductive hormones in relation to environmental exposure to mercury. Blood and semen samples were collected from 529 male partners of pregnant women living in Greenland, Poland and Ukraine between May 2002 and February 2

Consultation training of nurses for cardiovascular prevention - A randomized study of 2 years duration.

The aim of this study was to increase patients' adherence to the treatment of hypertension through the consultation training of nurses. Thirty-three nurses were included in the study. In the intervention group (IG), 19 nurses took part in a 3-day residential training course on the Stages of Change model, Motivational Interviewing and guidelines for cardiovascular prevention, and recruited 153 pati

Biofilm formation by Staphylococcus epidermidis on peritoneal dialysis catheters and the effects of extracellular products from Pseudomonas aeruginosa.

Biofilm formation by Staphylococcus epidermidis is a cause of infections related to peritoneal dialysis (PD). We have used a PD catheter flow-cell model in combination with confocal scanning laser microscopy and atomic force microscopy to study biofilm formation by S. epidermidis. Adherence to serum-coated catheters was four times greater than to uncoated ones, suggesting that S. epidermidis binds

Palmitic acid suppresses apolipoprotein M gene expression via the pathway of PPARβ/δ in HepG2 cells.

It has been demonstrated that apolipoprotein M (APOM) is a vasculoprotective constituent of high density lipoprotein (HDL), which could be related to the anti-atherosclerotic property of HDL. Investigation of regulation of APOM expression is of important for further exploring its pathophysiological function in vivo. Our previous studies indicated that expression of APOM could be regulated by plate

Certified Reference Material IAEA-446 for radionuclides in Baltic Sea seaweed

A Certified Reference Material (CRM) for radionuclides in seaweed (Fucus vesiculosus) from the Baltic Sea (IAEA-446) is described and the results of the certification process are presented. The K-40, Cs-132, U-234 and Pu239+240 radionuclides were certified for this material, and information values for 12 other radionuclides (Sr-90, Tc-99, Pb-210 (Po-210), Ra-226, Ra-228, Th-228, Th-230, Th-232, U-

Support and process in individual placement and support: A multiple case study.

Objective: This multiple case study investigated support and process in the Individual Placement and Support (IPS) approach from individual client, longitudinal and Person-Environment-Occupation (PEO) model perspectives. Participants: Five IPS-participants, or cases, with severe mental illness (SMI) who worked a minimum of 4 hours a week entered the study. Methods: A multiple data collectio

Appearance of remodelled and dendritic cell-rich alveolar-lymphoid interfaces provides a structural basis for increased alveolar antigen uptake in chronic obstructive pulmonary disease.

RATIONALE: The alveolar pathology in chronic obstructive pulmonary disease (COPD) involves antigen-driven immune events. However, the induction sites of alveolar adaptive immune responses have remained poorly investigated. OBJECTIVES: To explore the hypothesis that interfaces between the alveolar lumen and lymphoid aggregates (LAs) provide a structural basis for increased alveolar antigen uptake i

Bosonic and Fermionic Dipoles on a Ring

We show that dipolar bosons and fermions confined in a quasi-one-dimensional ring trap exhibit a rich variety of states because their interaction is inhomogeneous. For purely repulsive interactions, with increasing strength of the dipolar coupling there is a crossover from a gaslike state to an inhomogeneous crystal-like one. For small enough angles between the dipoles and the plane of the ring, t

A life-course study of cognitive reserve in dementia: Dementia incidence in inpatient registers and mmse test scores in a clinical study in sweden

Cognitive reserve helps mitigate the impact of pathology on the clinical expression of dementia. Education and occupational complexity are considered as contributors to reserve, although it has been argued that cognitive reserve is likely formed over the life-course. A life-course model of cognitive reserve in dementia risk has not yet been tested. We apply a life-course model and examine if schoo

Population-based screening for colorectal cancer with faecal occult blood test-do we really have enough evidence?

INTRODUCTION: Population-based randomised controlled trials (RCT) have shown that invitation to biennial screening with faecal occult blood testing (FOBT) during 10 or more years reduced colorectal cancer-specific mortality. These results have stimulated plans to introduce mass screening in various countries; however, none of these trials has been able to show any reduction of total mortality, whi

Abandoned and illegitimate, a double mortality penalty? Mortality of illegitimate infants in the foundling hospital of Madrid, La Inclusa (1890-1935)

This paper examines the existence of a mortality penalty for illegitimate abandoned infants in the Foundling Hospital of Madrid, La Inclusa, during the period 1890-1935, in the context of the mortality experience of the city. A rich dataset on the life histories of all infants abandoned in the city of Madrid (almost 60,000 children), nominally linked to births, has allowed the study of the determi

The Role of Metaphor in the Structuring of Emotion Concepts

Conceptual metaphor theory (CMT) is one of the most prolific frameworks in the study of emotion concepts. Following the seminal work of Lakoff and Johnson (1980) and subsequent work by Kövecses (1986, 1990) and Kövecses and Lakoff (1987), an impressive number of studies in cognitive linguistics and psycholinguistics have sought to document and confirm the claim that conceptual metaphor (CM) struct

Gene expression under thermal stress varies across a geographic range expansion front.

Many ectothermic species are currently expanding their distributions polewards due to anthropogenic global warming. Molecular genetic mechanisms facilitating range expansion under these conditions are largely unknown, but understanding these could help mitigate expanding pests and disease vectors, or help explain why some species fail to track changing climates. Here, using RNA-seq data, we examin