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Time Trends for Incidence and Net Survival of Cervical Cancer in Sweden 1960-2014 - A Nationwide Population-Based Study

Background: The aim was to investigate time trends for incidence and long-term net survival in the morphologic subtypes and stages of cervical cancer in Sweden during the period 1960 to 2014. Methods: Women with invasive cervical cancer were identified through the Swedish Cancer Registry. Incidence and net survival were calculated according to morphology, age at diagnosis, and FIGO stage at diagno

Physical activity changes the deposited fractions of particles in the respiratory tract of adults and children

Exposure to ambient air pollution can cause a numberof health problems and may be particularly dangerous to susceptible population groups such as children. Health effects caused by air pollution are criticallydependent on both the deposited fraction (DF) of the inhaled particles and in what region of the respiratory tract the deposition takes place. With increasing physical activity, the breathing

Maternal race and pre-eclampsia : Cohort study and systematic review with meta-analysis

Objectives: To examine the association between race and pre-eclampsia and gestational hypertension after adjustment for factors in maternal characteristics and medical history in a screening study from the Fetal Medicine Foundation (FMF) in England, and to perform a systematic review and meta-analysis of studies on pre-eclampsia. Design: Prospective observational study and systematic review with m

Conditions for uptake of evidence-based knowledge in municipal care for older people in Sweden : a developmental evaluation

Objective: The objective of this paper is to describe the initial phase of a long-term collaboration initiative between a municipality and the Faculty of Medicine at a university in Sweden. The overall ambition of the collaboration is to strengthen the quality of care for older people. The concrete goal is to equip academically trained registered health care professionals (HCP) with tools for tran

Motivation, Knowledge Sharing, and Need Satisfaction in Groups

Research confirms that there are many forms of motivation associated with various organizational outcomes, and that there are various ways in which motivation can be supported. Self-determination theory shows that autonomous motivation is related to many important organizational outcomes and that the support of basic psychological needs helps to develop the motivations even further. However, addit

Islet Autoantibody Levels Differentiate Progression Trajectories in Individuals with Presymptomatic Type 1 Diabetes

Our previous data-driven analysis of evolving patterns of islet autoantibodies (IAbs) against insulin (IAA), glutamic acid decarboxylase (GADA) and islet antigen 2 (IA-2A) discovered three trajectories characterized by either multiple IAbs (TR1), IAA (TR2), or GADA (TR3) as the first appearing autoantibodies. Here we examined the evolution of IAb levels within these trajectories in 2,145 IAb-posit

Testosterone deficiency and metabolic disturbances in men who fathered a child by use of donated spermatozoa

Dose-response association between level of impairment of semen quality and risk of morbidity or premature death has been reported. Therefore, it can be presumed that men utilizing donated spermatozoa, i.e. patients with non-obstructive azoospermia, are at highest risk for adverse health outcomes. To evaluate the risks of prescription of medications for common metabolic disturbances and testosteron

Making sense with social robots : Extending the landscape of investigation in HRI

The aim of this position paper is to propose a reflection on how to account for and investigate the many ways in which interaction between robots and humans requires co-ordination, negotiation or reformulation of meanings emerging in the ongoing interaction. Towards this aim, we argue, a perspective shift may be needed: to frame interactions as social engagements whose meaning can only be understo

Amplification of CDK4 and MDM2 : a detailed study of a high-risk neuroblastoma subgroup

In neuroblastoma, MYCN amplification and 11q-deletion are important, although incomplete, markers of high-risk disease. It is therefore relevant to characterize additional alterations that can function as prognostic and/or predictive markers. Using SNP-microarrays, a group of neuroblastoma patients showing amplification of one or multiple 12q loci was identified. Two loci containing CDK4 and MDM2

On the (lack of) correspondence between syntactic clauses and intonational phrases

This paper discusses the syntax–prosody mapping at the clause-level, or the potential absence thereof. In particular, the paper reexamines the validity and the necessity of the clause-level mapping constraint, MatchClause, proposed in Match Theory (Selkirk 2009, 2011). First, it will be shown, based on the results of previous empirical studies, that data from embedded clauses in Japanese do not pr

A climate risk analysis of Earth's forests in the 21st century

Earth's forests harbor extensive biodiversity and are currently a major carbon sink. Forest conservation and restoration can help mitigate climate change; however, climate change could fundamentally imperil forests in many regions and undermine their ability to provide such mitigation. The extent of climate risks facing forests has not been synthesized globally nor have different approaches to qua