In this perspective article, we provide recommendations for strengthening the policy framework for protecting the Baltic Sea from agricultural nutrient pollution. The most striking weakness is the lax implementation of prescribed abatement measures, particularly concerning manure management, in most countries. Institutions of the EU should also be leveraged for achieving Baltic Sea Action Plan (BS

Drawing on the IR theories of norm translation and strategic narratives, this article focuses on how states translate international norms to their own advantage by producing strategic narratives to advance their soft power ambitions abroad. Using the example of Feminist Foreign Policy (FFP), the article compares Sweden, Canada, France, and Mexico in their attempts to translate international femini

The longevity of the almost 100-year-old Ålandic autonomy has been attributed to, among other things, its ability to evolve and adapt to changing circumstances. This position can be problematized and qualified in at least four ways: firstly, most initiatives to develop the autonomy have come from the Ålandic and not the Finnish side; secondly, the processes leading up to the adoptions of new Auton

The rule of law in the EU is not only substantive and formal, it is also procedural. From the early years of European integration until now – and this through the interpretative lens of either the terse Article 31 ECSC or the robust Article 19 TEU - the procedural rule of law has always been thriving and jolting in the case law of both the European Coal and Steal Community (ECSC) Court and the Cou

The aim of this study was to investigate whether incretins, at physiological levels, affect hepatic and/or extrahepatic insulin clearance. Hepatic and extrahepatic insulin clearance was studied in 31 double incretin receptor knockout (DIRKO) and 45 wild-type (WT) mice, which underwent an Intravenous Glucose Tolerance Test (IVGTT). A novel methodology based on mathematical modeling was designed to

Context. Under certain conditions, stellar radial velocities can be determined from astrometry, without any use of spectroscopy. This enables us to identify phenomena, other than the Doppler effect, that are displacing spectral lines. Aims. The change of stellar proper motions over time (perspective acceleration) is used to determine radial velocities from accurate astrometric data, which are now

Background and purpose: Fibroblast growth factor 23 (FGF23) is an osteogenic hormone associated with chronic kidney disease and is an emerging risk factor for several cardiovascular diseases. The association of FGF23 with stroke is unclear. The aim of this study was to investigate the association of FGF23 with incident intracerebral hemorrhage (ICH). Methods: This was a nested case–control study o

Objectives: To investigate absolute and relative risk of serious infections in adult/elderly inflammatory bowel disease (IBD) diagnosed 2002–2017. Methods: Nationwide, register-based cohort study of Swedish patients with IBD compared with general population matched reference individuals with regard to time to first serious infection, equal to hospital admission. Multivariable Cox regression estima

Specific protocols define eligibility, conditioning, donor selection, graft composition and prophylaxis of graft vs. host disease for children and young adults undergoing hematopoietic stem cell transplant (HSCT). However, international protocols rarely, if ever, detail supportive care, including pharmaceutical infection prophylaxis, physical protection with face masks and cohort isolation or food

Background: Treatment of mentally disordered offenders (MDOs) is challenging as their behavior and clinical conditions can be traced to a complex constellation of major mental disorders, substance use and antisocial lifestyle. Finding subgroups of these offenders, which could guide treatment and risk assessment, is desirable. There are few long-term, prospective studies of risk factors for persist

Monitoring of individual biomarkers has the potential of explaining the hazard of survival outcomes. In practice, these measurements are intermittently observed and are known to be subject to substantial measurement error. Joint modelling of longitudinal and survival data enables us to associate intermittently measured error-prone biomarkers with risks of survival outcomes and thus plays an import

Women are at increased risk of complications after Cesarean section (CS) postpartum and in subsequent pregnancy and delivery. The overall aim of the thesis was to evaluate complications after CS, outline options for their management and to assess strategies to increase the rate of vaginal deliveries after CS (VBAC).Paper I was a prospective study where women were offered to have an additional appo

Context: Digitalization brings new opportunities and also challenges to software companies.Objective: Software companies have mostly focused on the technical aspects of handing changes and mostly ignoring the business model changes and their implications on software organization and the architecture. In this paper, we synthesize implications of the digitalization based on an extensive literature s

The interaction of simultaneous fracture and buckling constitutes problems at manufacturing and handling of thin foils. Buckling occurs as an additional event that complicates the prediction of the critical load that may lead to fracture. For most sufficiently thin foils the plastic slip occurs through the foil thickness which leads to reduction of the cross section width until the foil fails. The