Binding of urokinase plasminogen activator (uPA) to its cellular receptor, uPAR, potentiates plasminogen activation and localizes it to the cell surface. Focal plasminogen activation is involved in both normal and pathological tissue remodeling processes including cancer invasion. The interaction between uPA and uPAR therefore represents a potential target for anti-invasive cancer therapy. Inhibit

Threshold electron and total ion yield spectra are presented for the near C and O 1s edge photoexcitation of n- and iso-propanol. To our knowledge these are the first such data for iso-propanol, and represent the first direct measurement of the core ionization energies of these molecules by threshold photoelectron spectroscopy. In particular, the C 1s energies for n-propanol are found to be lower

Objective: Assessing lymph-node status in prostate cancer patients with high accuracy is only possible with surgical staging, despite the evolution of modern imaging techniques. The use of surgical staging has to be balanced against the complications of the procedure, the individual patient's risk for harbouring metastasesand the consequences for the treatment of the patient if such metastases are

BACKGROUND: High expression of the RNA-binding protein RBM3 has previously been found to be associated with good prognosis in breast cancer, ovarian cancer, malignant melanoma and colorectal cancer. The aim of this study was to examine the prognostic impact of immunohistochemical RBM3 expression in prostate cancer. FINDINGS: Immunohistochemical RBM3 expression was examined in a tissue microarray

SVENSKA universitetsledningar tenderar numera att prioritera lärosätets intäkter högre än allt annat, inklusive klassiska akademiska ideal som bildning och fri forskning. Därför fruktar vi att ett genomförande av Jan Björklunds planer kommer att leda till samma slags vansinne i Sverige som vi nu ser i Storbritannien.

Kulturkrönika om kortfilmerna på 2002 års Fantastisk Filmfestival i Lund.

Until 4 decades ago, the rates of stroke in low- and middle-income countries were considerably lower than those in more economically robust countries. In the intervening years, however, the rates of stroke in places such as southern India and rural South Africa have approximately doubled, whereas stroke rates in more economically developed nations have decreased. What is far more striking is that

Konstnären, slöjdläraren och fornforskaren Nils Månsson Mandelgren (1813-1899) vars samlingar förvaras på Folklivsarkivet dokumenterade en mängd olika föremål med teckningar och akvareller. Artikeln handlar om milstolpar och vägvisare ur denna samling.

INTRODUCTION: Complications after lumbar anaesthesia and epidural blood patch have been described in patients with congenital small spinal canal and increased epidural fat or epidural lipomatosis. These conditions, whether occurring separately or in combination, require magnetic resonance imaging for diagnosis and grading, but their clinical significance is still unclear. CASE PRESENTATION: A 35-y