Background: The International Federation of Gynecology and Obstetrics (FIGO) ovarian cancer staging system includes no sub-stage for lymph nodes (LN) as only distant disease manifestation. We explore the prognostic implication of LN as only stage IV classifier in serous ovarian cancer. Method: This is a nation-wide, population-based study on 551 women with serous stage IV cancers diagnosed between

Background: In many parts of the world, roadsides are regularly managed for traffic-safety reasons. Hence, there are similarities between roadsides and certain other managed habitats, such as wooded pastures and mown or grazed grasslands. These habitats have declined rapidly in Europe during the last century. For many species historically associated with them, roadsides may function as new primary

Diverse radiations of insects are often associated with adaptations to host plants, and well-resolved phylogenetic relationships are required to fully understand them. Palearctic Argynnis and related subgenera, together with North American Speyeria butterflies make up a radiation whose species hypotheses are confounded by shared wing colour patterns between sympatric populations of closely related

Type 2 diabetes (T2D) and adiposity associate with increased risk of several cancers, but the impact of competing risk of noncancer deaths on these associations is not known. We prospectively examined participants in the Malmö Diet and Cancer Study aged 44–73 years with no history of cancer at baseline (n = 26,953, 43% men). T2D was ascertained at baseline and during follow-up, and body mass index

It is a trivial fact that water is needed for decay of wood by brown rot fungi, but when this is looked at in more detail, there are several fundamental questions concerning water and decay that are not solved. The purpose of this study is to study how the wood-water interaction is changed during degradation of brown-rot fungi of Norway spruce (Picea abies (L) Karst.) grown at two different parts

A case study is used in this paper to study and analyse drawbacks and advantages of three different numerical fire models when used to model horizontal and vertical gas temperature distributions in a 1200m 2 large enclosure. The three methods are: a CFD model, a two-zone mode l and a multi-layer zone model. This is the first time the three models are used and compared in a large enclosure situatio

Soil organic matter (SOM) supports the Earth's ability to sustain terrestrial ecosystems, provide food and fiber, and retains the largest pool of actively cycling carbon. Over 75% of the soil organic carbon (SOC) in the top meter of soil is directly affected by human land use. Large land areas have lost SOC as a result of land use practices, yet there are compensatory opportunities to enhance prod

A well-functioning ventilation system is significant in achieving a healthy indoor environment. The air supply rate is one of the important factors in reducing the pollutant levels indoors. A study of the indoor environment has been made in new built apartments with modern energy-efficient mechanical supply and exhaust ventilation systems. Several parameters have been measured including the air su

Genome-wide association studies have linked lung cancer risk with a region of chromosome 15q25.1 containing CHRNA3, CHRNA5 and CHRNB4 encoding α3, α5 and β4 subunits of nicotinic acetylcholine receptors (nAChR), respectively. One of the strongest associations was observed for a non-silent single-nucleotide polymorphism at codon 398 in CHRNA5. Here, we have used pharmacological (antagonists) or gen

For chemically enhanced primary treatment (CEPT) with microsieving, a feedback proportional integral controller combined with a feedforward compensator was used in large pilot scale to control effluent water turbidity to desired set points. The effluent water turbidity from the microsieve was maintained at various set points in the range 12-80 NTU basically independent for a number of studied vari

We present a digital phase-locked loop (DPLL) operating from 2.8 to 3.8 GHz with an on-chip 40-MHz reference crystal oscillator. The DPLL makes use of a class-D digitally controlled oscillator and a digital-to-time converter with a single-bit (bang-bang) phase detector. The DPLL displays an excellent behavior in terms of in-band fractional spurs, which are consistently below -65 dBc across the tun

This paper investigates the causal effects of monetary policy on the British economy during the classical gold standard. Based on the narrative identification approach, I find that following a one percentage point monetary tightening, unemployment rose by 0.9 percentage points, while inflation fell by 3.1 percentage points. In addition, monetary policy shocks accounted for a third of macroeconomic

The electromagnetic environment of a tunnel junction can influence significantly the tunneling characteristics. We investigate experimentally a particular environment formed by tunnel junctions and compare the results with a theoretical model. We discuss Single Junction Thermometer and a two junction Coulomb Blockade Thermometer as examples.

The paper analyzes dynamic epistemic logic from a topological perspective. The main contribution consists of a framework in which dynamic epistemic logic satisfies the requirements for being a topological dynamical system thus interfacing discrete dynamic logics with continuous mappings of dynamical systems. The setting is based on a notion of logical convergence, demonstratively equivalent with c