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Background: Asthma is a chronic inflammatory disease with structural changes in the lungs defined as airway remodelling. Mast cell responses are important in asthma as they, upon activation, release mediators inducing bronchoconstriction, inflammatory cell recruitment, and often remodelling of the airways. As guinea pigs exhibit anatomical, physiological, and pharmacological features resembling hu

Background: The vast majority of covid-19 patients experience non-severe disease. Nonetheless, long-term symptoms may be common and the impact on quality of life is uncertain. This study aims to examine these aspects in a prospective, longitudinal cohort. Methods: Non-hospitalised patients with PCR-confirmed covid-19 were prospectively invited to self-report assessments of background data, symptom

Background: Whole-body skeletal radiography has traditionally been used in the management of multiple myeloma for defining treatment strategies. For several reasons, radiography has been replaced by computed tomography (CT) covering the same regions. Purpose: To evaluate the body mass index (BMI) adjusted effective radiation dose from two different methods of whole-body radiologic imaging for mult

This article critically reconstructs militant democracy’s ‘institutional conservatism’, a theoretical preference for institutions that restrain transformation. It offers two arguments, one historical and one normative. Firstly, it traces a historical development from a substantive to a procedural version of institutional conservatism from the traditional militant democratic thought of Schmitt, Loe

Introduction: Cyanide exposure can occur in various settings such as industry and metallurgy. The primary mechanism of injury is cellular hypoxia from Complex IV (CIV) inhibition. This leads to decreased ATP production and increased reactive oxygen species production. The brain and the heart are the organs most affected due to their high metabolic demand. While the cardiac effects of cyanide are w

Cancer plasticity is now a recognized new hallmark of cancer which is due to disturbances of cell differentiation programs. It is manifested not only in various forms like the best-known epithelial-mesenchymal transition (EMT) but also in vasculogenic and megakaryocytic mimicries regulated by EMT-specific or less-specific transcription factors such as HIF1a or STAT1/2. Studies in the past decades

In the pre-modern period of Western Europe, while the manor system gradually disintegrating, the private ownership of land was established. On this basis, the land right market saw increasing prosperity. The categorization of different types of land right transactions in Western Europe rooted in Roman law, and can be corresponded to the traditional land right transactions in China. This categoriza

Purpose of review: The study aims to provide a summary of recent developments for diagnosing and managing posterior cortical atrophy (PCA). We present current efforts to improve PCA characterisation and recommendations regarding use of clinical, neuropsychological and biomarker methods in PCA diagnosis and management and highlight current knowledge gaps. Recent findings: Recent multi-centre consen

The purpose of the study was to evaluate whether students with intellectual disabilities (ID) can improve their arithmetic skills by participating in an arithmetic intervention programme, theoretically founded on explicit instruction (EI) and administered via an application developed for tablet computers. The intervention study used a randomised controlled trial design (RCT) (n = 30, aged 10-16, 1

The Swedish Society of Uroradiology has revised their computed tomography (CT) guidelines regarding iodine contrast media-induced acute kidney injury (CI-AKI). They are more cautious compared to the European Society of Urogenital Radiology and the American College of Radiology since the actual risk of CI-AKI remains uncertain in patients with moderate to severe kidney damage due to a lack of prosp

One dominant economic concept in China states that yeomanry is the most efficient and equitable land tenure system while tenancy system not only causes landlord to exploit tenant farmers but also leads to low production efficiency. However, this paper questions the arguments for a yeomanry system. Appling the theory of optimal ownership structure on farms, this paper discusses the total surpluses

依据侨资企业数据库及其计量分析,对侨资企业的侨缘禀赋、资源禀赋和市场禀赋三个发展阶段进行了回顾总结;分析了在目前中国投资环境变化下侨资企业的转型、投资趋向、桥梁作用以及从制造业到服务业的发展趋势。认为目前国内投资环境出现深刻的变化,外资优惠政策取消,劳动力与环境治理等经营成本提高,经济开放加深,内需增强。侨资企业面临地理转移与产业转型,侨资从制造业主导到服务业兴起,从出口导向转到依托国内市场发展,其竞争力从利用中国生产要素比较优势转向全球产业链中形成集群优势,海外华商在中国面临剧变中的新机遇。

Vi lever i en tid när gränsöverskridande rättsförhållanden blir en allt mer naturlig del av vår vardag. Med det ökade antalet internationella rättsförhållanden ökar också antalet potentiella tvister som har anknytning till mer än ett land. Makar med olika medborgarskap kanske kommer att vilja skiljas och den köpta produkten från det andra landet kanske var felaktig. När tvister av den här typen sk

近世中国地权具有多层次的权益与功能,相互关联,彼此促进。最基本的是耕作权,在流动与交易中实现土地与劳动力的动态结合,租佃制就是其中一项以未来劳动收入或土地收益贴现的农地租赁制度。其次是土地增值权益,由于未来收益具备产权保障与激励,并可通过交易而变现,从而促进了人们对土地的投资。再次,以土地为中介的多样化交易形式具有跨期调剂的金融功能,满足了农民的融通需求,在一些交易中还萌生了推动地权交易的票据化现象。地权明晰促进土地流动;地权形态的多层次性促进其可交易性;多样化交易形式又推动地权与生产要素的动态组合,从而提高土地产出与经济效率。也因此,土地在流动与资源配置中增进了产权所有者的各种权益与财产的安全性,并提供多样化选择。由于农地的权能是多层次的,并事关过去和未来的长时期分配,因此,如果没有明确界定的地权及其收益分配,土地的流转与交易就会出现障碍而受阻。