The Effects of Chemotherapy on B Cells and T Cells in Blood and Tumor Tissue in Patients with Pancreatic Cancer – from Diagnosis to Terminal Disease
En viss typ av immuncellsansamling i tumörer, så kallade tertiära lymfoida strukturer (TLS), hos patienter med bukspottkörtelcancer verkar inte alltid vara så gynnsamt som forskning tidigare visat. Förekomst av många TLS i tumören kunde i studien kopplas till kortare överlevnad och kan möjligen bero på att cellgiftsbehandling förändrar funktionen TLS. I denna studie studerades två typer av immuncPancreatic cancer (PC) is a devastating disease and is almost always synonymous with a poor outcome. Chemotherapy is the standard treatment and is administered in either an adjuvant or palliative setting. However, nearly all patients, regardless of treatment intent, eventually develop chemoresistance. Little is known about the events causing chemoresistance, but increased knowledge is essential fo
