The tumor microenvironment of brain metastases has become a focus in the development of immunotherapeutic drugs. However, countless brain metastasis patients have not experienced clinical benefit. Thus, understanding the immune cell composition within brain metastases, and how the immune cells interact with each other and other microenvironmental cell types, may be critical for optimizing immunoth

In human proteomics, substantial efforts are ongoing to leverage large collections of mass spectrometry (MS) fragment ion spectra into extensive spectral libraries (SL) as a resource for data independent acquisition (DIA) analysis. Currently, such initiatives in equine research are still missing. Here we present a large-scale equine SL, comprising 6394 canonical proteins and 89,329 unique peptides

INTRODUCTION: Maternal SARS-CoV-2 infection can affect pregnancy outcome, but the placental response to and the effect of timing of infection is not well studied. The aim of this study was to investigate the placental levels of inflammatory and cardiovascular markers in pregnancies complicated by SARS-CoV-2 infection compared to non-infected pregnancies, and to investigate whether there was an ass

The current climate crisis is pressuring policymakers to outline what a post-fossil economy might entail. In Norway, many have pointed towards the salmon farming industry as a central part of the country’s green transition. At the same time, the industry has shifted towards increasing use of feed imports from Brazilian soy plantations - the second largest driver of deforestation in the country. Ex

China has established itself as the most important partner of many African countries. However, it is often labelled as a purely self-interested actor, who helps authoritarians stay in power. This thesis aims to enhance our understanding of the nature of China’s development finance through a two-step analysis. First, I investigate the allocation of Chinese aid to African countries, examining its re

Corporate sustainability (CS) has gained widespread recognition, coinciding with an increased focus on climate change. The media plays an important role in shaping public perceptions and policies regarding CS, the extent of non-financial information disclosure, and influencing how industries are viewed. However, the pharmaceutical manufacturing sector is significantly under-researched in relation

Making live, single-celled organisms fluoresce Protist is a term for a type of organism that has a nucleus and is not an animal, plant or fungus. Most protists are single-celled and can be found in all types of environments across the planet. Protists are highly diverse and understudied, and researching protists directly from the environment has many challenges. One method for researching microbe

The Module Learning With Errors (MLWE)-based Key Encapsulation Mechanism (KEM) Kyber is NIST's new standard scheme for post-quantum encryption. As a building block, Kyber uses a Chosen Plaintext Attack (CPA)-secure Public Key Encryption (PKE) scheme, referred to as Kyber.CPAPKE. In this paper we study the robustness of Kyber.CPAPKE against key mismatch attacks.We demonstrate that Kyber's security

The landscape of healthcare is experiencing a digitalization shift, transferring many medical activities to the patients’ homes, a phenomenon commonly referred to as Hospital-at-Home. While Internet of Things (IoT) devices facilitate the building of such systems, there is a need for powerful middleware that encapsulates device-to-device communication, and enables the construction of user-friendly,

Severe babesiosis with 9.8% parasitemia was diagnosed in a patient in the Netherlands who had previously undergone splenectomy. We confirmed Babesia venatorum using PCR and sequencing. B. venatorum was also the most prevalent species in Ixodes ricinus ticks collected around the patient's home. Our findings warrant awareness for severe babesiosis in similar patients.

The spread of tick-borne disease (TBD) is escalating globally, driven by climate change and socio-economic shifts, underlining the urgency to improve surveillance, diagnostics, and control strategies. Ticks can transmit a range of pathogens increasing the risk of transmission of human and veterinary diseases such as Lyme disease, tick-borne encephalitis, theileriosis, anaplasmosis, or Crimean-Cong

In the 1980ies much effort was made to get a, till then, unknown Viking Age silver hoard into the University Museum of Lund for registration. It was a large hoard consisting of over 900 coins, jewelry and hacksilver. We succeeded to have the hoard on display a few days in 1986.Thereafter the hoard was collected again by the finders and its further destiny is unknown. This is very much to regret asIn the 1980s much effort was made to get an, until then, unknown Viking Age silver hoard into the University Museum of Lund for registration. It was a large hoard consisting of over 900 coins, jewelry and hacksilver. We succeeded to have the hoard on display a few days in 1986.Thereafter the hoard was collected again by the finders and its further destiny was unknown. This was very much to regret

Background: Production of anti-phosphatidylserine (anti-PS) antibodies has been associated with malaria and can aggravate pathology. How these autoantibodies develop during early childhood in a malaria context is not known. We examined levels of anti-PS IgG and IgM antibodies in a longitudinal cohort of mother-baby pairs during birth, in the infants at 2.5, 6 months, and in mothers and their babie

Changes in land cover and land use (LULC) are one of the main drivers of erosion and runoff. How ever, most research has relied on short-term observations and only focused on one or two land cover types. We investigated the long-term trade-off between common agricultural land covers (sugarcane, pasture, and soybean), runoff, and soil loss rates. We compared these to native forest (wooded Cerrado)

When performing in situ remediation, different fluids are injected into the ground. The injections can affect the properties of the ground, such as opening up new fractures and reactivating old ones. The fluids also differ in viscosity and density and could possibly clog some of the pores or fractures, thus affecting the groundwater flow. We have measured hydraulic conductivity and compared our re