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'... this ambitious project definitely succeeds in putting together coherently a relatively recent body of research, and in arguing that a new policy approach to development is needed: one that puts knowledge accumulation at its core, that recognises the complex nature of learning processes and the need of new institutions to stimulate them. For the many who believe in the urgency of revising deve
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This paper discusses the importance of global-local linkages for the development of indigenous production in cultural clusters by analyzing the interplay between the indigenous film production cluster in Toronto, Canada, and Hollywood's runaway productions. Global-local linkages are at the forefront of the current debate in cluster studies, the discussion has so far had only a limited impact on th
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AbstractCystic fibrosis (CF) is caused by mutations in the anion channel and protein regulator CFTR. The most common co-morbidity in CF is CF-related diabetes (CFRD) affecting ~50% of adult patients. The etiopathology of CFRD is largely unknown but the destruction of the exocrine pancreas is thought to contribute. However, the hypothesis that CFTR has a direct role in the endocrine pancreas has no
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The effect of Ca++, Mg++, K+ and SO=4, and of serum, on the activity of testis hyaluronidase in a carbonic acid-bicarbonate buffer with pH 7.4 was investigated with the turbidimetric method. The ions were added in amounts corresponding to the serum concentration of the ion in question.The turbidity of hyaluronic acid was not modified by the investigated ions nor by serum up to 0.10 ml.The hyaluron
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This observational study assessed the relationship between nighttime, early-morning and daytime chronic obstructive pulmonary disease (COPD) symptoms and exacerbations and healthcare resource use. COPD symptoms were assessed at baseline in patients with stable COPD using a standardised questionnaire during routine clinical visits. Information was recorded on exacerbations and healthcare resource u
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Objective: The aim was to study whether perceived environmental barriers to outdoor mobility affect changes in sense of autonomy in participation outdoors among community-dwelling older people over a two-year period. Methods: Community-dwelling people aged 75–90 years (n = 848) in central Finland were interviewed on two occasions, face-to-face at baseline and over the telephone two years later. Pe
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Failure of soft tissue implants has been largely attributed to the influence of biomaterial surface properties on the foreign body response, but some implant complications, e.g. macrophage accumulation and necrosis, are still not effectively addressed with surface treatments to minimize deleterious biomaterial effects. We explored an alternative explanation for implant failure, linking biocompatib
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This edited volume examines the continued viability of international human rights law in the context of growing transnational law enforcement. With states increasingly making use of global governance modes, core exercises of public authority such as migration control, surveillance, detention and policing, are increasingly conducted extraterritorially, outsourced to foreign governments or delegated
