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Enzyme-based Approaches to Caries Prevention : Characterization and Disruption of Cariogenic Biofilms in In Vitro Models

Introduction: Enzyme-based approaches have shown promise in a more targeted alternative for treating oral diseases such as caries. Given the high global prevalence of caries, and ecological complexity of the oral microbiome, investigating selective treatment strategies is of significant interest. Background: The oral microbiome is a dynamic, polymicrobial community, dependent on ecological balance

Physiochemical characterization of polyester synthase enzymes and production of polyhydroxyalkanoate

Polyhydroxyalkanoate (PHA) synthases (PhaC) are the pivotal biocatalysts governing the biosynthesis of biodegradable polyesters. Current research on their structure and mechanisms remains limited, and the chemical mechanisms of all PHA synthases are still under debate. Despite some speculation, further physicochemical studies are needed to understand their structure and function. The primary obje

Sex Differences in Cardiovascular Disease: Single-cell RNA-seq analysis of Immune Responses Post-Myocardial Infarction

Immune Responses After a Heart Attack: Why Sex Matters Cardiovascular diseases remain the leading cause of death worldwide, and myocardial infarction (MI), or “heart attack,” is one of the most common forms of cardiovascular injury. Although MI begins with blocked blood flow and oxygen deprivation in the heart, much of the resulting damage is driven by the immune response that follows. After inju

Goods-to-Person or Goods-to-Robots? The Emergence of Robotic Pick-and-Place Technology in Automated Retail Warehouses

Retail warehouses are undergoing rapid technological transformation as companies respond to increasing pressure for faster order fulfilment, higher product variety, labour challenges, and improved operational efficiency. Goods-to-person systems have automated major parts of storage, retrieval, and internal material flow, yet the final item-level picking task at the workstation often remains manual

Mechanisms underlying cytosolic detection of mycobacterial infection

Tuberkulos: Utbrytarkung med järnkrona Det är aldrig roligt att vara sjuk. Ofta händer det vid ett dåligt tillfälle och är irriterande, exempelvis innan man ska åka på semester. Men det kan också vara väldigt allvarligt och livshotande. Oftast, när vi blir sjuka är det på grund av små mikroskopiska kryp – bakterier och virus. Vi kommer i kontakt med dessa varje dag, men lyckligtvis är de allra fl

Two Places, One Country, Yet So Far Apart: The Bonaire Climate Court Case

Following the Urgenda climate court case in the late 2010s, Greenpeace cooperated with a group of Bonairean residents to take the Dutch state to court again in 2024 in relation to climate neglect. According to the plaintiffs of the Bonaire case, the Caribbean island that is part of the country of the Netherlands is structurally neglected when it comes to climate adaptation and mitigation. On top o

Transport Justice and Multimodal Connectivity: A Case Study of the Copenhagen Metro Network

This thesis examines the transport justice in Copenhagen for multimodal transport using cycling and the metro network, to answer the research question ‘How equitable and equal is the bicycle access to high-capacity public transport metro stations in Copenhagen, and how is transport justice distributed?’. This question is answered by combining an expert interview, field observations, and geographic

Negotiating Place-Based Regional Development Policy: Multi-Level Governance and Institutional Isomorphism in RIS3 Implementation within the Eastern and Southern Netherlands

This research has explored the role actors from various scales have in the production of Research, Innovation and Smart Specialisation Strategies (RIS3) in the Eastern and Southern Netherlands through its multi-level governance framework. This could be worrying, as the influence from higher-scale actors could weaken RIS3’s ability to create place-based programmes. In order to gain an understanding

“An Endless Process of Proving Yourself”: The Construction and Negotiation of Legitimacy Among Female Entrepreneurs in China’s Cultural and Creative Industries

This thesis examines how female entrepreneurs in China’s cultural and creative industries construct and negotiate entrepreneurial legitimacy through narrative practices and identity work. Drawing on thirteen semi-structured interviews and eleven publicly available podcast accounts, covering twenty-four entrepreneurs in total, the study combines narrative analysis and discourse analysis to examine

Managing Post-Festival Residual Inventory: A Sequential Gate Model of Exit Decision-Making among Small Independent Retailers in China

Post-festival residual inventory is a recurring challenge for small independent retailers, especially when products are tied to specific festivals, gifting occasions or seasonal selling windows. Existing research has examined markdown pricing, product deletion, and reverse logistics primarily in large retail chains or formal supply-chain systems, while paying less attention to how small independen

On-Chip Runtime Frequency Feedback Closed-Loop Scheme for Low-Power Management

This thesis studies a runtime frequency feedback method for low-power digital systems. Conventional low-power designs usually reserve extra voltage and timing margins to ensure stable chip operation under process, voltage, temperature, and aging variations. However, fixed margins can also lead to unnecessary power consumption. To address this problem, this thesis proposes and implements a Runtime

”Det är ju inte något som någon har hittat på, men det är också det som är kittlande på något vis”. En kvalitativ studie av kvinnors konsumtion av true crime.

True crime är idag en vanlig form av vardaglig underhållning. Tidigare forskning har identifierat vilka motiven är till konsumtion av true crime samt att genren har inslag av exploatering, där kvinnor är den största konsumtionsgruppen. Däremot finns det en kunskapslucka gällande relationen mellan kvinnors konsumtion av true crime och hur de ställer sig inför genrens exploatering. Syftet med studie

Lathund för att möjliggöra användning av klimatförbättrad betong: Val av härdningsåtgärder utifrån projektförutsättningar

Klimatförbättrad betong erbjuder en av byggsektorns mest tillgängliga vägar till minskade utsläpp. Utnyttjandet begränsas dock i praktiken mer av produktionsförhållanden och tradition än av materialet i sig. Betongproduktion står för en betydande del av de globala koldioxidutsläppen. Cement, en av de huvudsakliga komponenterna i betong, går delvis att ersätta med tillsatsmaterial som mald granuleCement production accounts for a significant share of global carbon dioxide emissions, which has made the development of climate-improved concrete a central concern for the construction industry. Replacing part of the cement with supplementary cementitious materials reduces the climate impact, but slows the development of early-age strength, an effect particularly pronounced at low temperatures.

Creative Disruptions: Engaged anthropology and the role of fun and play in integration activities in Sweden

As Swedish migration laws become increasingly exclusionary, there exists integration activities which resist this rhetoric. This thesis looks at the activities carried out by Lunds Kommun social workers, and the organisation Interkultur i Lund. Through my own work as an intern with Lunds Kommun, in the Barn i Start team, I carried out 20 weeks of participant observation, and experienced fun, play,

Att vara eller icke vara pensionär - En socialantropologisk studie om övergången mellan yrkesliv och pension

Alla stora livsförändringar följs av perioder av tvetydighet och anpassning, i synnerhet pensionen. Idag ser vi stora demografiska förändringar till följd av att människor lever längre vilket gör det möjligt att anta att övergången från arbetsliv till pension har förändrats och fortsatt kommer att förändras. Syftet med uppsatsen är att förstå hur svenska pensionärer upplever och anpassar sig till

En alternativ hierarki: incels, maskulinitet och värde. En socialantropologisk studie om hur incels konstruerar och organiserar maskulinitet och socialt värde

Den här uppsatsen undersöker hur incels på ett internetforum konstruerar och organiserar maskulinitet och socialt värde i relation till det. Baserat på observationer i det största incelforumet i incelosfären, ämnar den att utreda aspekter av hur de skapar sin sociala verklighet online. Med hjälp av Connells maskulinitetsteori och teorin om värde och hierarki av Haynes och Hickel granskas vikten avThis thesis examines how incels on an internet forum construct and organize masculinity and social value in relation to it. Based on observations in the biggest incel forum in the incelosphere, it aims to unravel aspects of how they create their online social reality. Using Connell’s masculinity theory and the theory of value and hierarchy by Haynes and Hickel, this thesis intends to shed light on

What is all the fuzz about? An anthropological study of furries fursona construction

This thesis explores the furry fandom and, more specifically, fursona construction and realization of the furries’ “fursona”. The furry fandom is a community of people with a “fan-like interest” in media centering anthropomorphic animals, and members of the fandom are called furries. Drawing on the individual experiences of furries through nine semi-structured interviews, the study aims to give an

Number concentration of gold nanoparticles in suspension : SAXS and spICPMS as traceable methods compared to laboratory method

The industrial exploitation of high value nanoparticles is in need of robust measurement methods to increase the control over product manufacturing and to implement quality assurance. InNanoPart, a European metrology project responded to these needs by developing methods for the measurement of particle size, concentration, agglomeration, surface chemistry and shell thickness. This paper illustrateThe industrial exploitation of high value nanoparticles is in need of robust measurement methods to increase the control over product manufacturing and to implement quality assurance. InNanoPart, a European metrology project responded to these needs by developing methods for the measurement of particle size, concentration, agglomeration, surface chemistry and shell thickness. This paper illustrate

Sticky measurement problem : number concentration of agglomerated nanoparticles

Measuring the number concentration of colloidal nanoparticles (NPs) is critical for assessing reproducibility, enabling compliance with regulation, and performing risk assessments of NP-enabled products. For nanomedicines, their number concentration directly relates to their dose. However, the lack of relevant reference materials and established traceable measurement approaches make the validation