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Novel Function of CtXyn5A from Acetivibrio thermocellus: Dual Arabinoxylanase and Feruloyl Esterase Activity Occur in the Same Active Site

Uncharacterized side activities of enzymes can have significant negative effects on reaction products and yields. Hence, their identification and characterization is crucial for the development of successful reaction systems. Here, we report the presence of feruloyl esterase activity in CtXyn5A from Acetivibrio thermocellus besides its well-known arabinoxylanase activity for the first time. Both r

IHACRES, GR4J and MISD-based multi conceptual-machine learning approach for rainfall-runoff modeling

As a complex hydrological problem, rainfall-runoff (RR) modeling is of importance in runoff studies, water supply, irrigation issues, and environmental management. Among the variety of approaches for RR modeling, conceptual approaches use physical concepts and are appropriate methods for representation of the physics of the problem while may fail in competition with their advanced alternatives. Co

What keeps insects small? Time limitation during oviposition reduces the fecundity benefit of female size in a butterfly

Laboratory studies of insects suggest that female fecundity may increase very rapidly with adult size and that mass may often increase close to exponentially with time during larval growth. These relationships make it difficult to see how realistic levels of larval mortality can outweigh the fecundity benefit of prolonged growth. Hence, it is unclear why many insects do not become bigger. In this

Reduction in Volume of Nucleus Basalis of Meynert Is Specific to Parkinson’s Disease and Progressive Supranuclear Palsy but Not to Multiple System Atrophy

Objectives: To study in vivo gray matter (GM) volumes of the nucleus basalis of Meynert (nbM) in different parkinsonian syndromes and assess their relationship with clinical variables. Methods: T1-weighted magnetic resonance images from patients with progressive supranuclear palsy (PSP, N = 43), multiple system atrophy (MSA, N = 23), Parkinson’s disease (PD, N = 26), and healthy controls (HC, N =

Influence of Age and Genetic Background on Ethanol Intake and Behavioral Response Following Ethanol Consumption and During Abstinence in a Model of Alcohol Abuse

Genetic background and age at first exposure have been identified as critical variables that contribute to individual vulnerability to drug addiction. Evidence shows that genetic factors may account for 40–70% of the variance in liability to addiction. Alcohol consumption by young people, especially in the form of binge-drinking, is becoming an alarming phenomenon predictive of future problems wit

First-year mortality in incident dialysis patients : results of the Peridialysis study

BACKGROUND: Controversy surrounds which factors are important for predicting early mortality after dialysis initiation (DI). We investigated associations of predialysis course and circumstances affecting planning and execution of DI with mortality following DI.METHODS: Among 1580 patients participating in the Peridialysis study, a study of causes and timing of DI, we registered features of predial

Prevalence of Abdominal Obesity in Chinese Middle-Aged and Older Adults with a Normal Body Mass Index and Its Association with Type 2 Diabetes Mellitus : A Nationally Representative Cohort Study from 2011 to 2018

Background: Few studies have focused on the prevalence of abdominal obesity in Chinese middle-aged and older adults with a normal body mass index (BMI). Furthermore, it is still unclear whether abdominal obesity is an independent risk factor for type 2 diabetes mellitus (T2DM). Participants with a normal BMI are usually neglected during assessments of abdominal obesity-associated T2DM risk since t

Anatomy of the coronary sinus with regard to cardiac resynchronization therapy implantation

Knowledge of the coronary sinus (CS) anatomy is crucial for implantation of cardiac resynchronization therapy (CRT). Obstacles to CS entry, such as the Eustachian ridge and Thebesian valve, as well as within the CS, such as Vieussen’s valve and the vein of Marshall, are important to understand and differentiate during implantation or to identify earlier by imaging. Anatomic knowledge is mandatory

The Influence of Age on Cerebral Tissue Oxygenation in Vasovagal Syncope and Orthostatic Hypotension

Age-related physiological impairment increases susceptibility to syncope. We tested the hypotheses that cerebral oxygenation during orthostatic provocation, as well as the level at which syncope occurs, differs according to age. Non-invasive hemodynamic monitoring and cerebral oximetry were applied during a head-up tilt test in 139 patients with vasovagal syncope (mean (SD) 45, (17) years, 60%-fem

EcoDesign and the Ten Golden Rules: Generic advice for merging environmental aspects into product development

The most important moment in product development is when demands and specifications are decided for the product that is being planned. The specification defines the goal for the product development process. It is a very important steering opportunity for the continuing work and for environmentally driven demands that are to be addressed in the product development phase. The designers are said to h

Realization of axially defined GaInP/InP/InAsP triple-junction photovoltaic nanowires for high-performance solar cells

III-V semiconductor-based planar multi-junction solar cells synthesized to match the solar spectrum, increase absorption, and reduce thermalization loss are today's world-record efficiency solar cells. Realizing similarly performing multi-junction III-V nanowire (NW) solar cells would require significantly less material and is more sustainable at lower cost than planar solar cells. The NW geometry

Strategy for the multiplicity of degrowth

This chapter starts with outlining a degrowth vision for social-ecological transformation. It then traces the existing discussion on strategy in the degrowth movement and explains why it is important to think about strategy. Its key contribution is a conceptualiation strategy, which builds on and is closely aligned with our understanding of degrowth. Finally, it introduces the book and its structu

Från välfärdsstat till välfärdsmix, från statskyrka till civilsamhällesaktör

När Svenska kyrkan, den gamla lutherska statliga institutionen för tro och tillhörighet, ges ny inramning i ett välfärdssamhälle som förändras – förändras då även bilden av kyrkans sociala ansvarstagande?I detta kapitel är ambitionen att beskriva Svenska kyrkans roll i förhållande först till ”välfärdsstaten” och sedan till den välfärdsmix eller den ”välfärdspluralism” som präglar förhållandena ida

Diakoni - reflektion och praktik

I dagens välfärdspluralism antar idéburna organisationer roller som gemenskapsbyggare, röstbärare och serviceleverantörer. Det socialpolitiska landskapet är under ständig förändring – något som påverkar kyrkan och dess diakonala arbete. I kyrklig diakoni ryms praktik och reflektion, teologisk och socialpolitisk. Hur gestaltas detta? Vilka verksamheter prioriteras, hur organiseras och leds det diak

Se (inte bara) upp!

Att rapportera resultat ser de flesta i dagens samhälle som en självklar plikt. Många offentligfinansierade verksamheter styrs enligt en marknadslogik som bygger på kontraktsbaserade uppdrag som bland annat innebär en granskning av hur skattemedlen används. Redovisning sker genom mer eller mindre ingående kontroll med syftet att säkra den kvalitet man beställt och att visa att eftersträvade result